Attachment 1 - Minimum Essential Characteristics.docx
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- Solicitation number
- PANDHA-26-P-0000-035226
- Issued by
-
Defense Health Agency
About this file
This is a Request for Information (RFI) response document outlining minimum essential characteristics for a High-Density Microelectrode Array (MEA) System procurement by the United States Army Medical Research Institute of Chemical Defense (USAMRICD) through the Defense Health Agency Contracting Activity (DHACA).
The government seeks a complete MEA system capable of detecting, monitoring, and analyzing intracellular electrochemical activity with an electrode density exceeding 1,000 electrodes, simultaneous recording/readout/stimulation capabilities, and a minimum sampling frequency of 10 kHz per electrode. The system must support 3D tissue penetration technology for recording within spheroids, organoids, and tissue slices at depths greater than a single layer, and be compatible with excised brain, heart, and skeletal muscle tissue. The procurement includes one MEA unit with an integrated mini-incubator maintaining 37°C with 5% CO2; sample holders with net sizes of 1000/60, 1000/90, 300/60, and 300/90; five single-well microchip plates with 3D tissue technology and well diameters of at least 25mm; a high-performance Windows 11 workstation with 4TB SSD and GDPR5 graphics card; analysis software with perpetual licensing and spike-sorting capabilities; and a high-resolution monitor exceeding 2000x1000 resolution. The vendor must provide comprehensive training within 30 days of delivery and deliver all items within 12 weeks post-award. The government issued an RFI on March 24, 2026, with a closing date of April 1, 2026, and received no qualified responses. The procurement is designated as NAICS 334516 (Analytical Laboratory Instrument Manufacturing) with Product and Service Code 6640 (Laboratory Equipment and Supplies), and the government intends to sole-source to 3Brain US LLC pending evaluation of any submitted capabilities statements.
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Text version
Requested Information / Minimum Essential Characteristics:
We are seeking information on systems that meet the following minimum characteristics. Please describe your company's ability to provide a system that includes the following components and features:
· High-Density Microelectrode Array (MEA) System (Quantity: 1)
· Primary Function: Capable of detecting, monitoring, and analyzing intracellular electrochemical activity and membrane potentiation.
· Performance:
* Electrode density greater than 1,000 electrodes.
* Simultaneous recording, readout, and stimulation capabilities.
* Minimum sampling frequency of 10 kHz per electrode.
* Integrated stimulation from at least two (2) separate programmable channels.
· Compatibility:
* Compatible with 3D tissue penetration technology (e.g., micropillars) for recording activity within spheroids, organoids, and tissue slices at depths greater than a single layer.
* Suitable for use with excised tissue slices, including brain, heart, and skeletal muscle.
· Environmental Control:
* Includes an associated mini-incubator or housing with active heating and cooling to maintain a stable environment of 37°C with 5% CO2 for long-term recording sessions.
· Compatible Sample Holders and Plates
· Sample Holders (Quantity: 1): A set of holders with various net sizes, including 1000/60, 1000/90, 300/60, and 300/90, to accommodate different test objects.
· Single-Well Microchip Plates (Quantity: 5): Plates incorporating 3D tissue technology with a well size of at least 25mm in diameter.
· Integration Components (Quantity: 1): All necessary components to integrate the sample holders, nets, and plates with the primary MEA device.
· Software and Workstation (Quantity: 1)
· Software:
* Must be capable of sorting and analyzing spikes from all electrodes without requiring external support or additional programming requirements (e.g., Python).
* Includes a perpetual license that is compatible with future software versions.
· Workstation:
* A high-performance workstation operating on Windows 11.
* Includes a 4TB Solid State Drive (SSD) and a GDDR5 graphics card.
* TAA compliance is preferred.
· Monitor: A high-resolution monitor (>2000x1000) suitable for viewing imaging data.
· Interface: All necessary interfaces for the complete integration of MEA components, system, and software.
· Services and Delivery
· Training: A comprehensive training session on system function and use to be conducted no later than thirty (30) days after USAMRICD confirms receipt of all items. Training may be performed remotely or on-site.
· Delivery: All items must be delivered within 12 weeks post-award.
· Extended Warranty
· Please provide information on availability extended warranties.
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