Attachment 1. SOW.pdf

Statement of Work

Title - Supplies and Maintenance for Tecniplast Individually Ventilated Caging (IVC) Systems

1.0 Background Statement

This mission of the National Institutes of Environmental Health Sciences is to discover how the environment affects people in order to promote healthier lives.

The vision of the National Institutes of Environmental Health Sciences is to provide global leadership for innovative research that improves public health by preventing disease and disability from our environment.

The Comparative Medicine Branch (CMB) at the NIEHS is responsible for management of the NIEHS animal care and use program, which includes facility management, animal procurement and housing, animal health surveillance and disease diagnosis, clinical veterinary services, rodent breeding, technical and surgical assistance, embryo transfer, rederivation and cryopreservation, animal imaging, behavioral phenotyping, quality assurance of animal food, bedding, and water, and professional advice to the Institute on important animal issues. CMB also supports the scientific staff by providing training for investigators and technicians, quality assurance support for research projects, consultation with investigators planning animal research projects and administrative and professional staffing for the Institute Animal Care and Use Committee (ACUC).

The CMB plans and conducts research appropriate to these functions and participates in the training of residents in an ACLAM approved laboratory animal medicine training program. The NIEHS Animal Care and Use Program is fully accredited by AAALAC International. CMB supports over 200 active animal research projects for scientists in the Division of Intramural Research.

The National Institute of Environmental Health Sciences currently houses approximately 40,000 rodents in 17,500 cages, utilizing the Tecniplast Individually Caging (IVC) systems for all standard housing. NIEHS animal care staff change approximately 533,000 Tecniplast cage units (cage, feed hopper, lid) and 910,000 Tecniplast water bottles each year. In the process of assembly and disassembly of these cage units and water bottles and their associated component parts, the NIEHS cage processing operation handles approximately 6,840,000 component parts each year. Thus, only caging components specifically manufactured for use with the Tecniplast IVC system are acceptable under this procurement. Additionally, existing cage logistical equipment (cage transport racks, bottle transport racks, cage processing racks) are specifically designed for the transport and processing of the Tecniplast cage and water bottle styles that we have in use at NIEHS and are the only replacement type acceptable under this procurement. This solicitation is for the replacement parts, consumable items, and equipment required to maintain the use of the Tecniplast IVC systems.

2.0 Objectives

2.1 NIEHS needs a centralized purchasing mechanism for Tecniplast IVC system replacement parts, consumable items, and equipment.

2.2 The qualified contractor shall have a demonstrated history of distributing each of the required replacement parts, consumables, and equipment in the quantities required as listed in this SOW.

2.3 The qualified contractor shall provide documentation validating that each style of replacement part provided by them properly functions while in use with each style of Tecniplast IVC system in use at NIEHS.

2.4 The qualified contractor shall provide support over the telephone, in person, on-site, and via email. This support must be available Monday thru Friday 8:00 AM to 4:00 PM, excluding federal holidays. Response time for call back shall be within 2 hours of service call being placed.

Please refer to the Statement of Work for additional information.

3.0 Specific Requirements

3.1 The qualified contractor must provide documentation that demonstrates a history of validated proper function of all replacement parts, consumable items, and equipment listed in this requirement (See section 3.11) while in use in conjunction with the Tecniplast IVC systems utilized at NIEHS.

3.2 All replacement parts, consumable items, and equipment must be constructed/manufactured of the same materials and of the same grade, color, and appearance as those specifically listed in this requirement.

3.3 All replacement parts, consumable items, and equipment must be of identical dimensions and identical weight as those listed in this requirement.

3.4 All replacement parts, consumable items, and equipment must be new (not previously used) to ensure that no pathogens derived from animals housed at other institutions are introduced to NIEHS research animals.

3.5 All replacement parts, consumable items, and equipment must be packaged/labeled to indicate part number.

3.6 All replacement parts, consumable items, and equipment must be received in original packaging from the production facility, or otherwise identified in a manner that clearly indicates no prior use.

3.7 The qualified contractor must provide documentation that demonstrates a history of distributing all replacement parts, consumable items, and equipment listed in this requirement in the quantities listed in this requirement, and within a timely manner.

3.8 The qualified contractor must provide documentation that demonstrates a history of validated proper function of all replacement parts and equipment following repeated sanitation at water temperature in excess of 180 degrees Fahrenheit (oF) in cage processing equipment while interacting with associated detergents, as well as following multiple autoclave cycles.

3.9 The qualified contractor must provide documentation that demonstrates a history of providing onsite technical support for all replacement parts, consumable items, and equipment. The contractor will provide support over the telephone, in person, on-site, or via email. Qualified contractor representatives shall be available to provide support Monday thru Friday 8:00 AM to 4:00 PM EST, excluding federal holidays. Response time for call back shall be within two (2) hours of a support call being placed.

3.10 The qualified contractor will provide annual equipment calibration and troubleshooting support, as needed, which includes, but may not be limited to, ensuring proper operating requirements are met and verified in accordance with the 2011 Guide for the Care and Use of Laboratory Animals (The Guide) (http://grants.nih.gov/grants/olaw/Guide-for-the-care-and-use-of-laboratory-animals.pdf).

3.11 Products included in this procurement:

Tecniplast Product Name Tecniplast Part number

Polysulfone Water Bottle with Silicone Ring (340 ml) ACBT0312SU

Green Plastic Universal card holders ACPCP24GM

Stainless Steel Bottle Cap with Green Seal ACCP6521GM

PUR Transparent Hose ACSCVF70M05UG

GM 500 80 cage w/ bottles DGM8OCPSU

2GR24 DD cage double decker rack DGR24DD

Polysulfone GreenRat cage "Double Decker" GR1800DDSU

Up deck for GR1800 "Double Decker" GR1800DECK

Stainless steel food hopper, for rats, GR1800 "Double Decker" GR1800FH

H TEMP top for GR1800 cage, equipped with plastic hatch GR18TOPDRSU

PUR Transparent hose 076mm D.76‐89 L=1100mm‐GRAY‐PACKAGED ACSCVF70M11 RUG

GR35 (35 cage rat rack) DGR35CPSU

GM500 change too GR900 70 cage rack DGR70CPSU

GM 500 160 cage rack DGM160CPSU

2GR12DD cage double decker rack DGR12DDCPSU

Polysulfone Cage Body GM500SU

Stainless Steel Wire Half Lid with integrated food hopper GM500LID

Polysulfone Sealsafe Plus Top with Bottle Depression GM500TOPSEALSU

Polysulfone Cage Body GR900SU

Stainless Steel Wire Lid GR900LID

Polysulfone Sealsafe Plus Top with Two Bottle Depressions GR900TOPSEALSU

DISP. CAGE PRE‐BEDDED W/ TEA‐BAG CORN COB ‐ 50PCS ‐ IRRADIATED USUM2PBCSBOX‐300

DISPOSABLE OVERTOP FOR DM500 DISPOSABLE CAGE 100 PCS PACK USUM2IVCTOPSBOX‐300

SUMC Single Piece IVC Top, sterile,100 per box USUM2IIVCTOPSBOX‐300

Disposable Food Hopper ‐ 100 per box ‐ USUMFHSBOX‐300

LABEL HOLDER UNIVERSAL IN PP FOR SUMC ‐ 100 PCS PACK UACPCP24PPLSBOX‐300

PP SINGLE‐USE WATER BOTTLE FOR DISPOSABLE CAGE ‐ 50 PCS PACK USUMACBTSTSBOX‐300

SUM2 Transport Top for Disposable Cage ‐ 100 per box USUM2TOPSBOX‐300

Replacement AERO Kit central column cage support with visual indicator 5 per pack U4‐00000590‐0BOX‐300

Replac Green silicone sleeve for vertical oval plenums+green rigid sleeve ‐10 pc U4‐00000589‐0BOX‐300

Smart Flow EMBOX110SF

Transport rack for double decker ACCATG16DDTS

80 cage GM 500 transport rack ACCATG80GMTS

Transport rack for GR900 ACCATG42GRTS

Bottle crates 9LBCBMP18SG4R

INTERFRAMEF (Interceptor frame for Easy Flow Smart Flow Air Handler) INTERFRAMEF

INTERFRAMERL (89 MM T Duct for Single Interceptor Rack) INTERFRAMERL

Hi Density presentation rack for Rack Washer Cat# ACCALATLS0sHD ACCALATLS02HD ACCALATLS02HD

Baby presentation rack ACCALATLS02HDAA1

Exhaust Prefilter for CS5Evo plus change station U4‐00000506‐0BOX‐300

Smart Flow pre‐filter U4‐08170‐01‐0‐0ABOX‐300

Top intake prefilter for CS5EVOPLUS change station 4‐00000505‐0

Flexible hose with silicon sleeve 150cm long for greenline racks Cat#

ACSCVF70M15RGM ACSCVF70M15RUG

Smartflow Hepa Filters for Greenline Cat. # U4‐00003095‐0‐300 U4‐00003095‐0‐300

POSITIVE ISOCAGE RACK 6COL 8ROW SINGLE SIDE ‐ USA PLAG ‐ FULLY EQUIPPED ISO48PFEUS

X‐Temp Cage Body (PFS) 1245ISOCAGE

Stainless Steel Lid with Welded Divider 1245ISOLID

Positive X‐Temp IsoCage Plastic Top with Valves,Hepa Filter,two Clamps (PFS) 1245ISOTOPP

400 ml bottle X‐Temp, in PFS silicone ring ACBT0402PFS

Cap, nozzle mm 25, hole mm 1,8, s/s ACCP2521

REMOVABLE DECON RACK FOR ISOCAGE 5LEV 4 COL PACKED ISODR20

Autoclavable H14 filters for ISO line‐irradiated 12.5 kGy UISOHEPAXTBOX‐300

Annual Platinum Service Agreement for Atlantis RW (7/1‐6/30)

4.0 Delivery Schedule

DELIVERABLE SOW REFERENCE FREQUENCY

Provide one (1) complete Operation and Maintenance

Manuals for each new piece of equipment.

3.0 1x upon equipment delivery

Provide support over the telephone, in person, on‐ site, or via email.

3.9

Monday ‐ Friday 8:00 AM to 4:00 PM

EST within 2 hrs of request

Provide annual equipment calibration 3.10 Annually

Provide equipment troubleshooting support 3.9 & 3.10 Monday ‐ Friday 8:00 AM to 4:00 PM

EST within 2 hrs of request