Attachment_01_Purchase_Description.pdf

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: Luminescence detection reagents for use in HTS viral assays

2. Background Information and Objective: HTS viral detection assays have previously been optimized at NCATS for viruses such as Rift Valley Fever Virus and Sars-CoV2 using these luminescent detection reagents. The objective is to use these reagents to screen more internal libraries and validate hits from previous screens.

3. Generic Name of Product: Luminescence detection reagents

4. Purchase Description:

Product Description Item # Brand Quantity Caspase-Glo(R) 3/7 Assay, 100ml G8092 Promega 6 Caspase-Glo(R) 3/7 Assay, 10 x 10ml G8093 Promega 2 RealTime-Glo(TM) MT Cell Viability Assay, 1000 RXN

G9713 Promega 4

Nano-Glo(R) Luciferase Assay, 10x100ml N1150 Promega 3

5. Salient characteristics: These products are being ordered in continuation of ongoing HTS antiviral screens. Changing brands or products would require complete re-optimization. As such, these are the products we require to continue expanding our screening efforts and move forward to lead compound optimization.

6. Quantity: See Item 4.

7. Delivery Date: July 20, 2023.