Attach 1_Salient Characteristics_Sprayer System.docx

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Sprayer for MALDI Imaging
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FA700021Q0083
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SALIENT CHARACTERISTICS: Sprayer System for MALDI

At minimum, the Sprayer System:

· Must be capable of trypsin and matrix deposition specifically for MALDI mass spectrometry imaging integration.

· Must have validated trypsin and matrix protocols for fresh-frozen and formalin-fixed, paraffin-embedded tissue.

· Must have a small droplet size (5-20 μm), be capable of high flow rate (robust) and high (up to 10 µm) spatial resolution imaging.

· Must allow for control of nozzle/spray temperature (capable of heated spray) and velocity for solvent for optimized analyte extraction and sample drying times

· Must have a high velocity, heated stage/tray.

· Must have a humidity chamber for enzymatic digestion integrated with a heated stage/tray.

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