A14 - Business Proposal Budget Template_TO_4.xlsx

XLSX spreadsheet 142 KB Posted Jan 25, 2022

Attached to: Manufacturing and Nonclinical Studies Support for the Development of Therapeutic Biotechnology Products (Biologics) for Neurological-related Disorders
Solicitation number: 75N95022R00013
Issued by: Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse

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File	Type	Posted
75N95022R00013_Amn 2_S.pdf	PDF	Feb 28, 2022
75N95022R00013_Amn 1_S.pdf	PDF	Feb 25, 2022
A24 - Electronic Invoicing Instructions.pdf	PDF	Jan 25, 2022
A7 - VAS Worksheet.pdf	PDF	Jan 25, 2022
A29 - STO 3 - ASO Manufacturing Task Order.pdf	PDF	Jan 25, 2022
A15 - Points-of-contact.pdf	PDF	Jan 25, 2022
A18 - NIH(RC)1 Final.pdf	PDF	Jan 25, 2022
A4 - Section K-Reps and Certs.pdf	PDF	Jan 25, 2022
A9 - NIH 2043.pdf	PDF	Jan 25, 2022
A22 - Suitability Roster.xlsx	XLSX spreadsheet	Jan 25, 2022
A21 - Nondisclosure Agreement.pdf	PDF	Jan 25, 2022
A13 - Business Proposal Budget Template_TO_3.xlsx	XLSX spreadsheet	Jan 25, 2022
A11 - Business Proposal Budget Template_TO_1.xlsx	XLSX spreadsheet	Jan 25, 2022
A10 - HHS Subcontracting Plan Template.docx	DOCX document	Jan 25, 2022
A30 - STO 4 - BPN-Biologics PK and Tox Task Order.v2.pdf	PDF	Jan 25, 2022
A27 - STO 1- Kickoff and Project Management Plan.pdf	PDF	Jan 25, 2022
A2 - Proposal Intent Response Form.pdf	PDF	Jan 25, 2022
A1 - Packaging and Delivery of Proposals for Use with the NIH eCPS website.pdf	PDF	Jan 25, 2022
A5 - Tech-Prop-Cost-Summary.pdf	PDF	Jan 25, 2022
A16 - Wage Rate Determination.pdf	PDF	Jan 25, 2022
A19 - NIH(RC)2 Final.pdf	PDF	Jan 25, 2022
RFP 75N95022R00013.pdf	PDF	Jan 25, 2022
A17 -Disclosure of Lobbying Activities.pdf	PDF	Jan 25, 2022
A26 - DEC Acknowledgment.pdf	PDF	Jan 25, 2022
A3 - Biologics_IDIQ_SOW.pdf	PDF	Jan 25, 2022
A6 - Summary-Related-Activities.pdf	PDF	Jan 25, 2022
A28 - STO 2 - AAV Manufacturing Task Order.pdf	PDF	Jan 25, 2022
A20 - SORN 09-25-0118.pdf	PDF	Jan 25, 2022
A12 - Business Proposal Budget Template_TO_2.xlsx	XLSX spreadsheet	Jan 25, 2022
A25 - DEC_Approved.pdf	PDF	Jan 25, 2022
A8_Additional Technical Proposal Instructions.pdf	PDF	Jan 25, 2022
A23 - Emp-sep-checklist.pdf	PDF	Jan 25, 2022

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TO4_SUMMARY

	SUMMARY OF PROPOSED COSTS		Attachment #14 - Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
	Contractor's Name**			Base Task -
Single-Dose Rat PK Study		Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study		Optional Task 2 (Study 3) - Multiple-Dose Rat PK Study		Optional Task 3 (Study 4) - Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)		Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis		Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK		Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK		Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK		Optional Task 9 (Study 10) -
GLP NHP Multi-Dose PK		Optional Task 10 (Study 11) -
Single-dose GLP toxicity study in rats		Optional Task 11 (Study 12) -
Single-dose toxicity GLP study in NHPs		TOTAL
	RFP No.**		CONTRACT YEAR 1	CONTRACT YEAR 1	CONTRACT YEAR 1	CONTRACT YEAR 1	CONTRACT YEAR 1	CONTRACT YEAR 2	CONTRACT YEAR 3	CONTRACT YEAR 2	CONTRACT YEAR 2	CONTRACT YEAR 2	CONTRACT YEAR 2	CONTRACT YEAR 3	CONTRACT YEAR 3
		Period ( dates)##	7/1/22	7/1/22	7/1/22	7/1/22	7/1/22	7/1/23	7/1/24	7/1/23	7/1/23	7/1/23	7/1/23	7/1/24	7/1/24
			Through	Through	Through	Through	Through	Through	Through	Through	Through	Through	Through	Through	Through
			6/30/23	6/30/23	6/30/23	6/30/23	6/30/23	6/30/24	6/30/25	6/30/24	6/30/24	6/30/24	6/30/24	6/30/25	6/30/25
	Direct Labor - Percent of Effort		$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
	Fringe Benefits - Percent of Effort		0	0	0	0	0	0	0	0	0	0	0	0	0	$0
	Direct Labor - Hourly		0	0	0	0	0	0	0	0	0	0	0	0	0	$0
	Fringe Benefits - Hourly		0	0	0	0	0	0	0	0	0	0	0	0	0	$0
	Total Direct Labor & Fringe Benefits		$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0

Overhead (Note 1) 0% $0 0% $0 0% $0 0% $0 0% $0 0% $0 $0 0% $0 $0 $0 $0 $0 $0 $0

Materials and Supplies	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Professional Travel	0	0	0	0	0	0	0	0	0	0	0	0	0	$0
Equipment	0	0	0	0	0	0	0	0	0	0	0	0	0	$0
Consultants	0	0	0	0	0	0	0	0	0	0	0	0	0	$0
Other Direct Costs	0	0	0	0	0	0	0	0	0	0	0	0	0	$0
Subcontracts	0	0	0	0	0	0	0	0	0	0	0	0	0	$0
Total Other Direct Costs	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0

Subtotal: Direct Labor, Fringe Benefits, Overhead , & Other Directs		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0	$0
Exclusion(s) From Base For G&A		0		0		0		0		0		0		0		0		0		0		0		0		0	$0
Adjusted Base for G&A		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0	$0
G&A (Note 2)	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	$0
Total Proposed Cost Excluding Fee		0		0		0		0		0		0		0		0		0		0		0		0		0	0
Proposed Fee/Profit	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	0%	0	$0
Total Proposed Cost Plus Fee/Profit		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0		$0	$0

NOTES:
1.	Not all organizations allocate indirect cost in the same way. It is important that you use the indirect rate structure applicable to your organization.
	For example, if you have a two tier indirect rate structure, then you will use a two tier structure when proposing indirect costs.
	Generally, Universities and Non-Profits have fringe benefit and G&A (or sometimes called F&A) rates, while For-Profit Companies can have
	various indirect rates such as fringe benefits, overhead, G&A, etc.

The base for overhead costs includes direct labor and fringe benefits. Please modify if your base is different.

If applicable, insert exclusions to the G&A base in row 26.

2.	If you have questions regarding indirect (F&A) rates see website: http://oamp.od.nih.gov/dfas/indirect-cost-branch/indirect-cost-submission
	This website also contains definitions, examples, and training.

LEGEND:
**	Please insert the Company's name and the RFP #.

## Please insert the Company's name and the RFP #.

TO4_LABOR - Percent of Effort

SUMMARY OF DIRECT LABOR	Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
AND FRINGE BENEFITS
PERCENT OF EFFORT
Contractor's Name**		Base Task

(Study 1) -

Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -
Multiple-Dose Rat PK Study	Optional Task 3 (Study 4) - Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK	Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK	Optional Task 9 (Study 10) -
GLP NHP Multi-Dose PK	Optional Task 10 (Study 11) -
Single-dose GLP toxicity study in rats	Optional Task 11 (Study 12) -

Single-dose toxicity GLP study in NHPs

									Contract Year One					Contract Year One					Contract Year One					Contract Year One					Contract Year One					Contract Year Two					Contract Year Three					Contract Year Two					Contract Year Two
	RFP No.**							7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/23	Through	6/30/24			7/1/24	Through	6/30/25			7/1/23	Through	6/30/24			7/1/23	Through
				CURRENT	ADJUSTED		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE		PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	PERCENT
OF	NUMBER	SALARY	FRINGE	FRINGE	SALARY	FRINGE
		EMPLOYEE	POSITION	BASE SALARY	BASE SALARY		EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST	RATE	COST	EFFORT	MONTHS	COST
	1			$0	$0		0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0	0%	$0	0%	12.00	$0
	2			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	3			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	4			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	5			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	6			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	7			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	8			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	9			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	10			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	11			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	12			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	13			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	14			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	15			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	16			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	17			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	18			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	19			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	20			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	21			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	22			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	23			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	24			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	25			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	26			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	27			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	28			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	29			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	30			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
	31			0	0		0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0	0%	0	0%	12.00	0
					SUBTOTALS =		0%		$0		$0	0%		$0		$0	0%		$0		$0	0%		$0		$0	0%		$0		$0	0%		$0		$0	0%		$0		$0	0%		$0		$0	0%		$0

THE FOLLOWING BOXES IN COLUMN "D" BELOW MAY BE USED TO

CALCULATE THE ADJUSTED BASE SALARY, AS INDICATED:

(Use of these cells will affect all of the adjusted base salary column; if individual

anniversary dates differ, the adjusted base salaries must be entered individually

in Column "D" of the spreadsheet and explained in the budget justification)

ANNUAL INCREASE FACTOR:	0.00%	-	Insert annual cost of living % and/or merit increases
			as applicable and explain the % in the budget justification

ANNUAL INCREASE DATE: 00/00/00 - Insert annual increase date.

NUMBER OF MONTHS AT NEXT ANNUAL INCREASE 0 - Insert number of months at the new salary.

*Adjust the number of months per period as recommended in the RFP.

TO4_LABOR - Hourly

SUMMARY OF DIRECT LABOR	Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
AND FRINGE BENEFITS
Hourly Rates
Contractor's Name**		Base Task

(Study 1) -

Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -
Multiple-Dose Rat PK Study	Optional Task 3 (Study 4) -
Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK	Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK	Optional Task 9 (Study 10) -
GLP NHP Multi-Dose PK	Optional Task 10 (Study 11) -
Single-dose GLP toxicity study in rats	Optional Task 11 (Study 12) -

Single-dose toxicity GLP study in NHPs

							Contract Year One					Contract Year One					Contract Year One					Contract Year One					Contract Year One					Contract Year Two					Contract Year Three					Contract Year Two					Contract Year Two
RFP No.**						7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/23	Through	6/30/24			7/1/24	Through	6/30/25			7/1/23	Through	6/30/24			7/1/23	Through	6/30/24
			CURRENT BASE	ADJUSTED	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE	NUMBER	NUMBER	SALARY	FRINGE	FRINGE
	EMPLOYEE	POSITION	HOURLY RATE	HOURLY RATE	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST	HOURS	MONTHS	COST	RATE	COST
1			$0.00	$0.00	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0	0.00	12.00	$0	0%	$0
2			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
3			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
4			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
5			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
6			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
7			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
8			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
9			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
10			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
11			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
12			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
13			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
14			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
15			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
16			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
17			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
18			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
19			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
20			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
21			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
22			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
23			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
24			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
25			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
26			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
27			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
28			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
29			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
30			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
31			0.00	0.00	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0	0.00	12.00	0	0%	0
				SUBTOTALS =	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0	0.00		$0		$0

THE FOLLOWING BOXES IN COLUMN "D" BELOW MAY BE USED TO

CALCULATE THE ADJUSTED BASE SALARY, AS INDICATED:

(Use of these cells will affect all of the adjusted base salary column; if individual

anniversary dates differ, the adjusted base salaries must be entered individually in

Column "D" of the spreadsheet and explained in the budget justification)

NUMBER OF HOURS FOR FULL TIME EQUIVALENT: 0 -- Insert your direct work year.

			Insert annual cost of living % and/or merit increases
ANNUAL INCREASE FACTOR:	0.00%	--	as applicable and explain the % in the budget
			justification

ANNUAL INCREASE DATE: 00/00/00 -- Insert annual increase date.

NUMBER OF MONTHS AT NEXT ANNUAL INCREASE 0 -- Insert number of months at the the new hourly rate.

*Adjust the number of months per period as recommended in the RFP.

TO4_Materials

SUMMARY OF MATERIALS AND SUPPLIES		Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
Contractor's Name**
RFP No.**
	Base Task

(Study 1) -

Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -
Multiple-Dose Rat PK Study	Optional Task 3 (Study 4) -
Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK	Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK	Optional Task 9 (Study 10) -
Single-dose GLP toxicity study in rats	Optional Task 9 (Study 11) -
GLP NHP Multi-Dose PK	Optional Task 11 (Study 12) -

Single-dose toxicity GLP study in NHPs

			Contract Year One			Contract Year One			Contract Year One			Contract Year One			Contract Year One			Contract Year Two			Contract Year Three			Contract Year Two			Contract Year Two			Contract Year Two			Contract Year Two			Contract Year Three			Contract Year Three
		7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/23	Through	6/30/24	7/1/24	Through	6/30/25	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24	7/1/24	Through	6/30/25	7/1/24	Through	6/30/25
		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit
	ITEM	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	TOTAL
1		$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00
2		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
3		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
4		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
5		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
6		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
7		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
8		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
9		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
10		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
11		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
12		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
13		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
14		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
15		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
16		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
17		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
18		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
19		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
20		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
21		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
22		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
23		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
24		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
25		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
26		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
27		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
28		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
29		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
30		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	$0.00
	TOTAL =			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00	$0.00

Please use current catalog, historical documentation, or vendor quotes.

Supporting documentation may be requested at a later date

&24&USUMMARY OF MATERIALS AND SUPPLIES

TO4_Travel

SUMMARY OF TRAVEL COSTS	Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
Contractor's Name**
RFP No.**

Cost Element Base Task (Study 1) -

Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -
Multiple-Dose Rat PK Study	Optional Task 3 (Study 4) -
Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK	Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK	Optional Task 9 (Study 10) -
Single-dose GLP toxicity study in rats	Optional Task 10 (Study 11) -
GLP NHP Multi-Dose PK	Optional Task 11 (Study 12) -
Single-dose toxicity GLP study in NHPs	TOTAL
		Contract Year One	Contract Year One	Contract Year One	Contract Year One	Contract Year One	Contract Year Two	Contract Year Three	Contract Year Two	Contract Year Two	Contract Year Two	Contract Year Two	Contract Year Three	Contract Year Three
		7/1/2022 - 6/30/2023	7/1/2022 - 6/30/2023	7/1/2022 - 6/30/2023	7/1/2022 - 6/30/2023	7/1/2022 - 6/30/2023	7/1/2023 - 6/30/2024	7/1/2024 - 6/30/2025	7/1/2023 - 6/30/2024	7/1/2023 - 6/30/2024	7/1/2023 - 6/30/2024	7/1/2023 - 6/30/2024	7/1/2024 - 6/30/2025	7/1/2024 - 6/30/2025
	Trip #	1	1	1	1	1	1	1	1	1	1	1	1	1
	Site
	Reason
	Airfare	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
	Lodging	0	0	0	0	0	0	0	0	0	0	0	0	0
	Meals	0	0	0	0	0	0	0	0	0	0	0	0	0
	Incidentals	0	0	0	0	0	0	0	0	0	0	0	0	0
	Ground Transport	0	0	0	0	0	0	0	0	0	0	0	0	0
	Total Per Trip	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
	No. of persons	0	0	0	0	0	0	0	0	0	0	0	0	0
	SUBTOTAL =	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0

Trip #	2	2	2	2	2	2	2	2	2	2	2	2	2
Site
Reason
Airfare	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Lodging	0	0	0	0	0	0	0	0	0	0	0	0	0
Meals	0	0	0	0	0	0	0	0	0	0	0	0	0
Incidentals	0	0	0	0	0	0	0	0	0	0	0	0	0
Ground Transport	0	0	0	0	0	0	0	0	0	0	0	0	0
Total Per Trip	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
No. of persons	0	0	0	0	0	0	0	0	0	0	0	0	0
SUBTOTAL =	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0

Trip #	3	3	3	3	3	3	3	3	3	3	3	3	3
Site
Reason
Airfare	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
Lodging	0	0	0	0	0	0	0	0	0	0	0	0	0
Meals	0	0	0	0	0	0	0	0	0	0	0	0	0
Incidentals	0	0	0	0	0	0	0	0	0	0	0	0	0
Ground Transport	0	0	0	0	0	0	0	0	0	0	0	0	0
Total Per Trip	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
No. of persons	0	0	0	0	0	0	0	0	0	0	0	0	0
SUBTOTAL =	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0
TOTAL COST =	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0	$0

Please review the RFP for the recommended number of trips and destinations if applicable.

Please use the company or institutional travel policy unless current Government Per Diem rates

are utilized. Please use current vendor quotes for airfare and other travel costs. Supporting

documentation may be requested at a later date.

TO4_Equipment

SUMMARY OF EQUIPMENT COSTS		Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
Contractor's Name**
RFP No.**
	Base Task

(Study 1) -

Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -
Multiple-Dose Rat PK Study	Optional Task 3 (Study 4) -
Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK	Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK	Optional Task 9 (Study 10) -
GLP NHP Multi-Dose PK	Optional Task 10 (Study 11) -
Single-dose GLP toxicity study in rats	Optional Task 11 (Study 12) -

Single-dose toxicity GLP study in NHPs

			Contract Year One			Contract Year One			Contract Year One			Contract Year One			Contract Year One			Contract Year Two			Contract Year Three			Contract Year Two			Contract Year Two			Contract Year Two			Contract Year Two			Contract Year Three			Contract Year Three
		7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/23	Through	6/30/24	7/1/24	Through	6/30/25	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24	7/1/24	Through	6/30/25	7/1/24	Through	6/30/25
		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit
	ITEM	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	TOTAL
1		$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00
2		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
3		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
4		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
5		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
6		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
7		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
8		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
9		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
10		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
11		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
12		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
13		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
14		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
15		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
16		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
17		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
18		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
19		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
20		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
21		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
22		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
23		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
24		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
25		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
26		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
27		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
28		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
29		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
30		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
	TOTAL =			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00	$0.00

All proposed equipment costs should include a justification and be based on current vendor quotes.

Supporting documentation may be requested at a later date.

&24&USUMMARY OF EQUIPMENT COSTS

TO4_Other Direct

SUMMARY OF OTHER DIRECT COSTS	Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
Contractor's Name**
RFP No.**

		Base Task (Study 1) -
Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -
Multiple-Dose Rat PK Study	Optional Task 3 (Study 4) -
Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -
GLP NHP Single-Dose PK	Optional Task 8 (Study 9) -
GLP Dog Multi-Dose PK	Optional Task 9 (Study 10) -
GLP NHP Multi-Dose PK	Optional Task 10 (Study 11) -
Single-dose GLP toxicity study in rats	Optional Task 11 (Study 12) -

Single-dose toxicity GLP study in NHPs

			Contract Year One			Contract Year One			Contract Year One			Contract Year One			Contract Year One			Contract Year Two			Contract Year Three			Contract Year Two			Contract Year Two			Contract Year Two			Contract Year Two			Contract Year Three			Contract Year Three
		7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/22	Through	6/30/23	7/1/23	Through	6/30/24	7/1/24	Through	6/30/25	7/1/23	Through	6/30/24	7/1/23	Through	6/30/24				7/1/23	Through	6/30/24	7/1/24	Through	6/30/25	7/1/24	Through	6/30/25
		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit		Unit	Unit
	ITEM	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	Price	Quantity	Subtotal	TOTAL
1		$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00	0	$0.00	$0.00
2		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
3		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
4		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
5		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
6		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
7		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
8		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
9		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
10		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
11		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
12		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
13		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
14		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
15		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
16		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
17		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
18		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
19		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
20		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
21		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
22		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
23		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
24		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
25		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
26		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
27		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
28		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
29		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
30		0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00	0	0.00	0.00
	TOTAL =			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00			$0.00	$0.00

Please use current catalog prices, or vendor quotes.

Supporting documentation may be requested at a later date.

&24&USUMMARY OF OTHER DIRECT COSTS

TO4_Consultants

SUMMARY OF CONSULTANT COSTS	Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
Contractor's Name**
RFP No.**

		Base Task (Study 1) -
Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -

Multiple-Dose Rat PK Study

				Contract Year One					Contract Year One					Contract Year One
			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23
	CONSULTANT	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal
(1)		$0			$0	$0	$0			$0	$0	$0			$0	$0
(2)		0			0	0	0			0	0	0			0	$0
(3)		0			0	0	0			0	0	0			0	$0
(4)		0			0	0	0			0	0	0			0	$0
(5)		0			0	0	0			0	0	0			0	$0
(6)		0			0	0	0			0	0	0			0	$0
(7)		0			0	0	0			0	0	0			0	$0
(8)		0			0	0	0			0	0	0			0	$0
(9)		0			0	0	0			0	0	0			0	$0
(10)		0			0	0	0			0	0	0			0	$0
	TOTAL =					$0					$0					$0

		Optional Task 3 (Study 4) -
Multiple-Dose Mouse PK Study	Optional Task 4 (Study 5) -
PD (Tissue Distribution in Mice)	Optional Task 5

(Study 6) (multi-year) - Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis

				Contract Year One					Contract Year One					Contract Year Two
			7/1/22	Through	6/30/23			7/1/22	Through	6/30/23			7/1/23	Through	6/30/24
	CONSULTANT	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal
(1)		$0			$0	$0	$0			$0	$0	$0			$0	$0
(2)		0			0	0	0			0	$0	0			0	$0
(3)		0			0	0	0			0	$0	0			0	$0
(4)		0			0	0	0			0	$0	0			0	$0
(5)		0			0	0	0			0	$0	0			0	$0
(6)		0			0	0	0			0	$0	0			0	$0
(7)		0			0	0	0			0	$0	0			0	$0
(8)		0			0	0	0			0	$0	0			0	$0
(9)		0			0	0	0			0	$0	0			0	$0
(10)		0			0	0	0			0	$0	0			0	$0
	TOTAL =					$0					$0					$0

Optional Task 5 (Study 6) (multi-year) -

Assay Development, and/or Qualification, and/or Validation, and/or Plasma and Tissue Sample Analysis	Optional Task 6 (Study 7) -
Dog GLP Single-Dose PK	Optional Task 7 (Study 8) -

GLP NHP Single-Dose PK

				Contract Year Three					Contract Year Two					Contract Year Two
			7/1/24	Through	6/30/25			7/1/23	Through	6/30/24			7/1/23	Through	6/30/24
	CONSULTANT	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal
(1)		$0			$0	0	$0			$0	$0	$0			$0	$0
(2)		0			0	0	0			0	0	0			0	0
(3)		0			0	0	0			0	0	0			0	0
(4)		0			0	0	0			0	0	0			0	0
(5)		0			0	0	0			0	0	0			0	0
(6)		0			0	0	0			0	0	0			0	0
(7)		0			0	0	0			0	0	0			0	0
(8)		0			0	0	0			0	0	0			0	0
(9)		0			0	0	0			0	0	0			0	0
(10)		0			0	0	0			0	0	0			0	0
	TOTAL =					$0					$0					$0

		Optional Task 9 (Study 9) -
GLP NHP Multi-Dose PK	Optional Task 10 (Study 10) -
Single-dose GLP toxicity study in rats	Optional Task 9 (Study 11) -

GLP NHP Multi-Dose PK

					Contract Year Two				Contract Year Two					Contract Year Three
				7/1/23	Through	6/30/24		7/1/23	Through	6/30/24			7/1/24	Through	6/30/25
	CONSULTANT	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal	Rate	# Hours	# Days	Travel	Subtotal
(1)		$0			$0	$0	$0			$0	$0	$0			$0	$0
(2)		0			0	0	0			0	0	0			0	0
(3)		0			0	0	0			0	0	0			0	0
(4)		0			0	0	0			0	0	0			0	0
(5)		0			0	0	0			0	0	0			0	0
(6)		0			0	0	0			0	0	0			0	0
(7)		0			0	0	0			0	0	0			0	0
(8)		0			0	0	0			0	0	0			0	0
(9)		0			0	0	0			0	0	0			0	0
(10)		0			0	0	0			0	0	0			0	0
	TOTAL =					$0					$0					$0

Optional Task 11 (Study 12) - Single-dose toxicity GLP study in NHPs

				Contract Year Three
			7/1/24	Through	6/30/25
	CONSULTANT	Rate	# Hours	# Days	Travel	Subtotal	TOTAL
(1)		$0			$0	$0	$0
(2)		0			0	0	$0
(3)		0			0	0	$0
(4)		0			0	0	$0
(5)		0			0	0	$0
(6)		0			0	0	$0
(7)		0			0	0	$0
(8)		0			0	0	$0
(9)		0			0	0	$0
(10)		0			0	0	$0
	TOTAL =					$0	$0

TO4_Subcontracts

SUMMARY OF SUBCONTRACTOR COSTS	Sample Task Order 4 – Pharmacokinetics and Toxicology Studies
Contractor's Name**
RFP No.**

		SUBCONTRACT #	Base Task (Study 1) -
Single-Dose Rat PK Study	Optional Task 1 (Study 2) -
Single-Dose Mouse PK Study	Optional Task 2 (Study 3) -

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File details come from the government source that posted it. Updated Jan 25, 2022.