B3 Purchase Description.doc

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: This acquisition is necessary to provide microscopy instruments the iPSC Neurodegenerative Diseases Initiative (INDI) Project within the new Center for Alzheimer’s Disease and Related Dementias.

2. Background Information and Objective: imaging technology improves to capture As part of the iPSC Neurodegenerative Disease Initiative, we plan to measure how neurodegeneration-related mutations alter protein networks of disease-relevant iPSC-derived cells. The most sensitive and scalable method to measure these changes is through a robotic microscope.

3. Generic Name of Product: Robotic Confocal Microscope Purchase Description:

· Salient characteristics All deliverables required under this contract shall be packaged, marked and shipped in accordance with Government specifications. At a minimum, all deliverables shall be marked with the contract number and Contractor name. The Contractor shall guarantee that all required materials shall be delivered in immediate usable and acceptable condition.

Vendor must be able to provide these specifications for the Nikon Eclipse Ci-L plus Microscope

· Must provide Nikon Eclipse CFI60 Infinity Optical System

· Must provide high luminescent white LED Illuminator with light intensity management feature, ECO mode, sleep mode.

· Must provide image capture button

· Must provide eyepieces with sleeve diameter of 30mm, CFI 10X (22), CFI 12.5X (16), CFI 15X (14.5), CFI UW 10X (25)

· Must provide following focusing tools: coaxial coarse/fine focusing, focusing stroke: 30 mm, coarse: 9.3 mm/rotation, Fine: 0.1 mm/rotation, Fine movement scale 1um, with coarse motion torque adjustable, refocusing function.

· Must provide intelligent sextuple nosepiece with analyzer slot.

· Must provide FOV 22mm with: C-TB binocular tube, C-TE2 ergonomic binocular tube (eyepiece port = 100.0, 50:50) via optional C-TEP2 DSC Port, C-TEP3 DSC Port C-0.55X. Inclination angle: 10-30 degree, Extension: up to 40mm.

· Must provide FOV 25mm with: C-TF Tinocular Tube F (eyepiece: port 100.0, 0:100) C-TT Trinocular Tube T (eyepiece port = 100:0, 20:80, 0:100)

· Must provide stages with: cross travel 78 (X) x 54 (Y) mm, with vernier calibration, stage handle height and torque adjustable for all stages, C-SR2S Right handle stage with 2S holder, C-CSR Right Handle Ceramic-coated stage, C-CSR1S Right Handle Ceramic-coated stage with 1S holder, C-H2L Specimen holder 2L (option), C-H1L Specimen Holder 1L (option)

· Must provide manual condenser with: Focusing stroke 27 mm, C-AB Abbe condenser, C-AR Achromat Condenser, C-DO Darkfield Condenser oil, C-DD Darkfield Condenser Dry, C-PH Phase Contrast Turret Condenser, C-AA Achromat/Aplanat, C-SA Slide Achromat Condenser 2-100X, C-SW Swing-out Achromat Condenser 1-100X, C-SWA Swing-out Achromat Condenser 2-100X, C-LAR LWD Achromat Condenser.

· Must provide brightfield, epi-fluorescence, darkfield, phase contrast, simple polarizing, and sensitive color polarizing observational methods.

· Must provide epi-fluorescence attachments: Cl-FL-2 Epi-fluorescence Attachment (4 filter cubes mountable), D-FL-2 U-EPI Epi-fluorescence attachment (6 filter cubes mountable, Terminator mechanism)

· Must provide D-LEDI Fluorescence LED Illumination system for Epi-illumination light source.

· Must provide 5.0W (Brightfield configuration) power consumption

· Must provide system with a maximum weight of 13.3kg.

· Must provide camera control software for tablet PC NIS-Elements L that is equipped with a scene mode that can automatically set the optimum shooting conditions for each observation method. with a network function, you can share images with a remote PC.

· Must provide DS10 Color Digital Camera 6000 x 3984 (23.9 MP)(Nikon F-Mount) USB-C.

· Must provide SOLA Light Engine (380-760) V-nIR with Liquid Light Guide (2.0 Meter), Computer Control of Light Intensity, Peak performance at 488nm (Blue), Peak performance at 500-600nm (Yellow / Green), Peak performance at 621nm (Red) Remote control, with Digital Display of Wavelength Intensity.

· Must provide Universal Epi Fluorescence Module SSE (DFL2UEPI) with: 6-Position Turret, Shutter, Aperature & Field Diaphragm, ND4, ND8, ND16, ET Sputter Ex 395/25 Dm T412 Em 431/28 (Alex 405), ET Sputter Ex 480/40 Dm T510 Em 535/50 (Alex 488), ET Sputter Ex 532/10 Dm T532 Em 590/50 (Alex 594), ET Sputter Ex 620/60 Dm T660 Em 700/75 (Alex 647)

· Must provide following objectives : CFI Plan Apo 2x / 0.1 / 8.5mm, CFI Plan Fluor 4x / 0.13 / 17.2mm, CFI Plan Fluor 10x / 0.30 / 16.0mm, CFI Plan Fluor 20x / 0.50 / 2.10, CFI Plan Fluor 40x / 0.75 / 0.66 Dry

· Must provide users to view live images from a remote site and have full control of the microscope including: remotely select a full array of objectives (from 1x-100x), and while viewing live images, stitch multiple fields of view into a large single high magnification image.

4. Delivery Date: Delivery date of 1 month after receipt of completed purchase order

5. Period of Performance: Manufacturer warranty for one calendar year beginning date of receipt.

6. Option(s): Not applicable Version 11-30-2016-1

FAR Part 11—Describing Agency Needs

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