Appendix One.pdf
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- Attached to
- National Institutes of Health (NIH) NeuroBioBank (NBB) Tissue Toxicology Testing Services
- Solicitation number
- 75N95024R00082
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This document is a Sources Sought notice for National Institutes of Health (NIH) NeuroBioBank (NBB) Tissue Toxicology Testing Services. The purpose is to obtain information on the availability and capabilities of qualified small business sources to perform this potential Research & Development (R&D) requirement. The key requirements include: receiving and tracking samples shipped from NBB Brain and Tissue Repositories, performing toxicological assays on human tissues (primarily post-mortem brain tissue, blood, and hair) to detect therapeutic drugs, drugs of abuse, and environmental toxins, and providing quantitative test results electronically on a monthly basis. The anticipated period of performance is one 12-month base period with three 12-month option periods. Interested companies are required to submit capability statements addressing the project requirements by May 20, 2024. This notice is for market research purposes only and does not constitute a solicitation or commitment to award a contract.
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Appendix One
REPRESENTATIVE LIST OF ANALYTES
10-Hydroxycarbazepine Acetaminophen Acetone Acetyl Fentanyl Alfentanil alpha-PVP Amitriptyline Amlodipine Amobarbital Amoxapine Amphetamine Atomoxetine Atropine Benzodiazepines Benztropine Beta-Phenethylamine Brompheniramine Bupivacaine Buprenorphine / Metabolite Bupropion Bupropion Metabolite Buspirone Butabarbital Butalbital Butorphanol
BZP
Caffeine Cannabinoids Carbamazepine Carbromal Carisoprodol Chlorpromazine Citalopram / Escitalopram Clomipramine Clonidine Clozapine Cocaine / Metabolites Cotinine Cyclobenzaprine Descarboethoxyloratadine Desipramine Desmethylcitalopram Desmethylclomipramine Desmethyldoxepin Desmethylmirtazapine Desmethylsertraline Desmethyltrimipramine Dextro / Levo Methorphan
Dextrorphan / Levorphanol Dicyclomine Diltiazem Diphenhydramine Donepezil Doxepin Doxylamine Duloxetine Duloxetine Breakdown Product
EDDP
Ephedrine / Pseudoephedrine Eszopiclone / Zopiclone Breakdown Ethanol Ethinamate Ethosuximide Ethotoin Ethylecgonine Ethylmorphine Etomidate Felbamate Fentanyl Flecainide Fluconazole Fluoxetine Fluvoxamine Gabapentin Breakdown Product Guaifenesin Haloperidol Hexobarbital Hydroxybupropion Hydroxychloroquine Hydroxyzine Ibuprofen Imipramine Isopropanol Ketamine Lacosamide Lamotrigine Laudanosine Levamisole Levetiracetam Lidocaine Loratadine Loxapine Maprotiline mCPP
MDA
MDEA
MDMA
MDPV
Meclizine Memantine Meperidine Mephedrone Mepivacaine Meprobamate Mescaline Mesoridazine Metaxalone Methadone Methamphetamine Methanol Methaqualone Methocarbamol Methoxetamine Methylecgonine Methylone Methylphenidate Metoclopramide Metoprolol Metronidazole Mexiletine Milnacipran Mirtazapine Monoethylglycinexylidide (MEGX) N-Acetylprocainamide Naltrexone - Free Naproxen Naproxen Breakdown Product Nicotine Nifedipine Norclozapine Norcodeine Norcyclobenzaprine Norfentanyl Norfluoxetine Norhydroxyzine Norketamine Normeperidine Norpseudoephedrine / Phenylpropanolamine Nortriptyline O-Desmethylvenlafaxine Ondansetron Opiates Orphenadrine Other Findings Oxycodone / Oxymorphone Papaverine
Paroxetine Pentazocine Pentobarbital Phencyclidine Pheniramine Phenobarbital Phensuximide Phentermine Phenylethylmalonamide (PEMA) Phenyltoloxamine Phenytoin
PMA
Primidone Procainamide Promazine Promethazine Propofol Propoxyphene Protriptyline Pyrilamine Quetiapine Quinidine Quinine Ramelteon Ramelteon M-II Rufinamide Salicylates Secobarbital Sertraline Strychnine Sufentanil Tetrahydrozoline
TFMPP
Theobromine Theophylline Thioridazine Thiothixene Ticlopidine Tiletamine Tramadol Tramadol Metabolite Trazodone Trihexyphenidyl Trimethoprim Trimipramine Venlafaxine Venlafaxine Metabolite Verapamil Xylazine Yohimbine Zaleplon
Zolazepam Zolpidem
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