PD_Purchase-Description (official).pdf

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Synthesis of GMP grade NCGC00413972
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75N95023Q00020
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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: Synthesis of 200 g of GMP grade NCGC00413972

2. Background Information and Objective: After showing efficacy and safety in various animal models of cancer, the team is ready to move forward and test the compound against pancreatic cancer and other conditions that involve an imbalance of macrophages giving rise to various disease states.

3. Generic Name of Product: NCGC00413972

N N

N

O N H

N

O

NCGC00413972

N-(3-(2-oxopyrrolidin-1-yl)propyl)-4-(6-phenylimidazo[1,5-a]pyrazin-3-yl)benzamide

4. Purchase Description: Synthesis of 200g of GMP grade NCGC00413972

5. Salient characteristics The final product should be >97% purity by NMR, LCMS and other analytical tools that help establish the identity and purity of the product.

6. Quantity: 200g

7. Delivery Date: 90 days after approval of order.

8. Period of Performance 90 days

9. Option(s): If positive results warrant additional amounts of compound, KareBay Biochem, Inc. will be contacted as they will have the required experience to deliver GMP NCGC00413972 at the appropriate time and amount.

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