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Annual Maintenance Agreement for Agilent 400 MHz NMR Spectrometer (NMR400-SN41271)
Solicitation number
75N95021Q00080
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TITLE: Annual Maintenance Agreement for Agilent 400 MHz NMR Spectrometer (NMR400-

SN41271).

SAM.GOV: https://beta.sam.gov/opp/e7ad3774a3084bc6bc61608c9d195dd2/view

RFQ: 75N95021Q00080

AMENDMENT No.: 01 AMENDMENT DATE: May 11, 2021 QUOTATION DUE DATE: 11:00 a.m., Eastern Time, on May 18, 2021 (Remains Unchanged)

ISSUED BY:

National Center for Advancing Translational Sciences, NIH NIDA Office of Acquisition, NCATS Section

BG 11601 RM 03C09 MSC 6012

11601 LANDSDOWN ST

BETHESDA MD 20852-6012

PRIMARY POINT OF CONTACT:

Renato Gomes, Contract Specialist Phone: (301) 451-2596 Email: renato.gomes@nih.gov

TO ALL OFFERORS:

The above-numbered solicitation is amended as set forth below. The hour and date specified for receipt of quotes REMAINS UNCHANGED.

Quoters must acknowledge receipt of this amendment on each copy of the quote submitted OR by separate letter or electronic communication which includes a reference to the solicitation and amendment numbers.

FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED

FOR THE RECEIPT OF QUOTES PRIOR TO THE HOUR AND DATE SPECIFIED MAY

RESULT IN REJECTION OF YOUR QUOTE.

If by virtue of this amendment you desire to change a quote already submitted, such change may be made by letter, provided each letter makes reference to the solicitation and this amendment, and is received prior to the time and date specified for receipt of quotes.

PURPOSE: To revise the Statement of Work (SOW) and provide answers to interested offeror questions.

All other terms and conditions of the Combined Synopsis/Solicitation remain unchanged.

MODIFICATION CHANGES

1. Combined Synopsis/Solicitation, Attachment – Statement of Work (SOW), Scope of Work, General Requirements, 1. Instrument, is hereby amended and replaced in its entirety as follows:

Agilent 400 MHz NMR spectrometer (Agilent (Varian) 400 MHz VNMRS with a Magnex 400/54/ASC magnet, Agilent 7600 sample changer, and XRTCA-0 Air-Jet VT unit).

https://beta.sam.gov/opp/e7ad3774a3084bc6bc61608c9d195dd2/view mailto:renato.gomes@nih.gov

RFQ: 75N95021Q00080

AMENDMENT No.: 01 AMENDMENT DATE: May 11, 2021 PROPOSAL DUE DATE: 11:00 a.m., Eastern Time, on May 18, 2021 (Remains Unchanged)

RESPONSES TO QUESTIONS

The Government has provided answers to interested offeror questions below. Note that many questions may have been combined, paraphrased, and/or summarized for brevity and clarity.

Interested Offeror Question 1: “Can you please provide the Agilent part number for this instrument?”

Government Answer to Interested Offeror Question 1: The NMR instrument does not have a single part number as systems are built to customer specs with the individual modules having serial numbers. This particular instrument is an Agilent (Varian) 400 MHz VNMRS with a Magnex 400/54/ASC magnet, Agilent 7600 sample changer, and XRTCA-0 Air-Jet VT unit. The revised SOW and the SOW with Track Changes is attached. Please refer to MODIFICATION CHANGES, 1., above.

STATEMENT OF WORK (SOW)

General Information

Title of Project:

Annual Maintenance Agreement for Agilent 400 MHz NMR Spectrometer (NMR400-SN41271)

Statement of Need and Purpose:

The National Center for Advancing Translational Sciences (NCATS) Division of Preclinical

Innovation (DPI), previously purchased the 400 MHz NMR spectrometer (SN41271) and associated non-cryogenic components.

Medicinal chemists in the DPI use the Nuclear Magnetic Resonance (NMR) instruments on a daily basis to collect compound data, as well as conduct more advanced NMR experiments overnight. Constant access to fully functioning NMR instruments is an imperative to maintain productivity in the successful pursuit of the DPI mission. As such, routine maintenance is of highest priority to ensure the NMR instruments operate properly. Furthermore, periodic upgrades and component replacement are required to prolong the instrument lifetime. In the event of a malfunction, this highly sophisticated and expensive instrument, as well as the associated components will require expert service.

To maintain these instruments in fully functioning, peak condition, scheduled preventive maintenance and service are required.

Background Information and Objective:

The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people’s health and save lives.

The National Center for Advancing Translational Sciences (NCATS) is a part of the National

Institutes of Health (NIH), which mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.

The Division of Preclinical Innovation (DPI) plans, conducts and uses both internal and contract resources to advance collaborative research projects across the preclinical phases of the translational science spectrum. Specifically, this division:

• Plans, conducts and collaborates on research to develop new methods and technologies to enhance preclinical processes.

• Plans, conducts and collaborates on research to evaluate existing and developing approaches, technologies, and processes in the preclinical spectrum.

• Supports training programs relevant to preclinical phases of translational science.

• Allocates DPI resources to preclinical extramural and intramural investigators.

• Collaborates with other NIH Institutes and Centers and the scientists they support.

• Consults with stakeholders, including patients, industry and regulators.

The DPI requires an annual service agreement to maintain the Agilent 400 MHz NMR spectrometer (Serial Number: NMR400-SN41271) in fully functioning order via preventative maintenance for one 12-month base year and three (3) 12-month successive option years.

Without such a contract in place, repair costs are extremely high and instrument downtime is much longer causing a significant decrease in scientific productivity.

Period of Performance:

The anticipated period of performance is:

Base Period: May 21, 2021 – May 20, 2022

Option Period 1: May 21, 2022 – May 20, 2023

Option Period 2: May 21, 2023 – May 20, 2024

Option Period 3: May 21, 2024 – May 20, 2025

Place of Performance:

The place of performance shall be:

NCATS/NIH

9800 Medical Center Dr

Rockville, MD 20850

Scope of Work

General Requirements:

Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, material, equipment, and facilities, not otherwise provided by the Government as needed to perform the Statement of Work below:

1. Instrument: Agilent 400 MHz NMR spectrometer (Agilent (Varian) 400 MHz VNMRS with a Magnex 400/54/ASC magnet, Agilent 7600 sample changer, and XRTCA-0 Air-Jet VT unit) Serial Number: SN41271 Service Agreement: CrossLab Silver Service Contract

Specific Requirements:

The Contractor shall provide service agreement coverage during each 12-month period including one (1) preventative maintenance (PM) visit and unlimited on-site hardware troubleshooting and repair with standard response time including parts and consumables for the repair for Agilent 400 MHz NMR spectrometer (Serial Number: NMR400-SN41271); specifically,

1. Contractor shall provide preventive maintenance, service repairs including emergency service repairs, and technical support between the hours of 8:00 AM and 5:00 PM of Monday through Friday, excluding Federal holidays.

2. On-site service and repairs shall be performed between the hours of 8:00 am and 5:00 pm on Monday through Friday, except Federal holidays.

3. Contractor shall use only OEM-certified parts and components for all preventive maintenance and repairs, except for consumables, at no additional cost to the Government.

4. Contractor shall be responsible for shipping and handling costs of each equipment instrument’s replacement parts and components.

5. The Contractor shall provide telephone support to isolate and resolve hardware and software problems.

6. The Contractor shall provide service center repair as applicable, at no additional cost to the Government.

7. The Contractor shall provide at no additional cost to the Government all necessary documentation, repair parts, spare parts, accessories, maintenance supplies, special tools, test and support equipment, travel and transportation, personnel skill requirements, and other related services required to maintain each instruments in fully functioning condition, except for costs of repairs occasioned by fault or negligence of the Government.

8. The services and preventive maintenance shall be performed by an Agilent service engineer in order to assure proper repair and operation of the system in accordance with manufacturer guidelines.

9. The Contractor shall perform one (1) preventive maintenance on-site inspection during each twelve-month period.

Government Responsibilities:

The Government will provide Contractor personnel reasonable facility access to the Agilent instrument for preventive maintenance, repair, and support services. Access will be restricted during federal holidays and after business hours.

Delivery or Deliverables:

Preventive maintenance and repairs as needed, as described in the “Specific Requirements” section above.

Reporting Requirements:

The Contractor shall provide one (1) validation report at the completion of each maintenance, repair or service visit for the Agilent instrument that describes the services performed on the instruments or components and certifies it to be in fully functioning, good condition.

Other Considerations:

Travel:

Travel costs shall be covered by Contractor at no additional cost to the Government .

General Information

Title of Project:

Annual Maintenance Agreement for Agilent 400 MHz NMR Spectrometer (NMR400-SN41271)

Statement of Need and Purpose:

The National Center for Advancing Translational Sciences (NCATS) Division of Preclinical

Innovation (DPI), previously purchased the 400 MHz NMR spectrometer (SN41271) and associated non-cryogenic components.

Medicinal chemists in the DPI use the Nuclear Magnetic Resonance (NMR) instruments on a daily basis to collect compound data, as well as conduct more advanced NMR experiments overnight. Constant access to fully functioning NMR instruments is an imperative to maintain productivity in the successful pursuit of the DPI mission. As such, routine maintenance is of highest priority to ensure the NMR instruments operate properly. Furthermore, periodic upgrades and component replacement are required to prolong the instrument lifetime. In the event of a malfunction, this highly sophisticated and expensive instrument, as well as the associated components will require expert service.

To maintain these instruments in fully functioning, peak condition, scheduled preventive maintenance and service are required.

Background Information and Objective:

The National Institutes of Health (NIH) is the nation’s leading medical research agency and the primary Federal agency whose mission is to seek fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability, conducting, supporting and making medical discoveries that improve people’s health and save lives.

The National Center for Advancing Translational Sciences (NCATS) is a part of the National

Institutes of Health (NIH), which mission it is to catalyze the generation of innovative methods and technologies that will enhance the development, testing and implementation of diagnostics and therapeutics across a wide range of human diseases and conditions.

The Division of Preclinical Innovation (DPI) plans, conducts and uses both internal and contract resources to advance collaborative research projects across the preclinical phases of the translational science spectrum. Specifically, this division:

• Plans, conducts and collaborates on research to develop new methods and technologies to enhance preclinical processes.

• Plans, conducts and collaborates on research to evaluate existing and developing approaches, technologies, and processes in the preclinical spectrum.

• Supports training programs relevant to preclinical phases of translational science.

• Allocates DPI resources to preclinical extramural and intramural investigators.

• Collaborates with other NIH Institutes and Centers and the scientists they support.

• Consults with stakeholders, including patients, industry and regulators.

The DPI requires an annual service agreement to maintain the Agilent 400 MHz NMR spectrometer (Serial Number: NMR400-SN41271) in fully functioning order via preventative maintenance for one 12-month base year and three (3) 12-month successive option years.

Without such a contract in place, repair costs are extremely high and instrument downtime is much longer causing a significant decrease in scientific productivity.

Period of Performance:

The anticipated period of performance is:

Base Period: May 21, 2021 – May 20, 2022

Option Period 1: May 21, 2022 – May 20, 2023

Option Period 2: May 21, 2023 – May 20, 2024

Option Period 3: May 21, 2024 – May 20, 2025

Place of Performance:

The place of performance shall be:

NCATS/NIH

9800 Medical Center Dr

Rockville, MD 20850

Scope of Work

General Requirements:

Independently and not as an agent of the Government, the Contractor shall furnish all the necessary services, qualified personnel, material, equipment, and facilities, not otherwise provided by the Government as needed to perform the Statement of Work below:

1. Instrument: Agilent 400 MHz NMR spectrometer (Agilent (Varian) 400 MHz VNMRS with a Magnex 400/54/ASC magnet, Agilent 7600 sample changer, and XRTCA-0 Air-Jet VT unit) Serial Number: SN41271 Service Agreement: CrossLab Silver Service Contract

Specific Requirements:

The Contractor shall provide service agreement coverage during each 12-month period including one (1) preventative maintenance (PM) visit and unlimited on-site hardware troubleshooting and repair with standard response time including parts and consumables for the repair for Agilent 400 MHz NMR spectrometer (Serial Number: NMR400-SN41271); specifically,

1. Contractor shall provide preventive maintenance, service repairs including emergency service repairs, and technical support between the hours of 8:00 AM and 5:00 PM of Monday through Friday, excluding Federal holidays.

2. On-site service and repairs shall be performed between the hours of 8:00 am and 5:00 pm on Monday through Friday, except Federal holidays.

3. Contractor shall use only OEM-certified parts and components for all preventive maintenance and repairs, except for consumables, at no additional cost to the Government.

4. Contractor shall be responsible for shipping and handling costs of each equipment instrument’s replacement parts and components.

5. The Contractor shall provide telephone support to isolate and resolve hardware and software problems.

6. The Contractor shall provide service center repair as applicable, at no additional cost to the Government.

7. The Contractor shall provide at no additional cost to the Government all necessary documentation, repair parts, spare parts, accessories, maintenance supplies, special tools, test and support equipment, travel and transportation, personnel skill requirements, and other related services required to maintain each instruments in fully functioning condition, except for costs of repairs occasioned by fault or negligence of the Government.

8. The services and preventive maintenance shall be performed by an Agilent service engineer in order to assure proper repair and operation of the system in accordance with manufacturer guidelines.

9. The Contractor shall perform one (1) preventive maintenance on-site inspection during each twelve-month period.

Government Responsibilities:

The Government will provide Contractor personnel reasonable facility access to the Agilent instrument for preventive maintenance, repair, and support services. Access will be restricted during federal holidays and after business hours.

Delivery or Deliverables:

Preventive maintenance and repairs as needed, as described in the “Specific Requirements” section above.

Reporting Requirements:

The Contractor shall provide one (1) validation report at the completion of each maintenance, repair or service visit for the Agilent instrument that describes the services performed on the instruments or components and certifies it to be in fully functioning, good condition.

Other Considerations:

Travel:

Travel costs shall be covered by Contractor at no additional cost to the Government .

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