G. Mod_2_5888985 -75N95021Q00046_Mod_and_questions.pdf

TITLE: Testing of compounds in rat pharmacokinetic experiments SAM.GOV: https://beta.sam.gov/opp/81904b5847a945c5bae4a9308da325e6/view

RFQ: 75N95021Q00046

AMENDMENT No.: 02 AMENDMENT DATE: January 29, 2021 PROPOSAL DUE DATE: 11:00 a.m., Eastern Time, on February 1, 2021 (Unchanged)

ISSUED BY:

National Center for Advancing Translational Sciences, NIH NIDA Office of Acquisition, NCATS Section

BG 11601 RM 03C09 MSC 6012

11601 LANDSDOWN ST

BETHESDA MD 20852-6012

PRIMARY POINT OF CONTACT:

Renato Gomes, Contract Specialist Phone: (301) 451-2596 Email: renato.gomes@nih.gov

TO ALL OFFERORS:

The above-numbered solicitation is amended as set forth below. The hour and date specified for receipt of quotes IS NOT EXTENDED.

PURPOSE: to respond to formal questions submitted in response to the solicitation.

All other terms and conditions of the Combined Synopsis/Solicitation remain unchanged.

RESPONSES TO QUESTIONS

The Government has provided answers below. Note that many questions may have been combined, paraphrased, and/or summarized for brevity and clarity.

1. Answer: In response to question regarding batches of samples, NCATS clarifies that it requires the testing of 20 (twenty) small molecule compounds in rat pharmacokinetic studies that would be sent to the contractors in 3 (three) to 6 (six) batches during the performance of the purchase order. The results of the study are to be provided in 1 (one) report for the 20 compounds detailing results from the pharmacokinetic studies. If the number of samples received at one time is a material factor in the contractor’s price, please address that in the quote.

https://beta.sam.gov/opp/81904b5847a945c5bae4a9308da325e6/view mailto:renato.gomes@nih.gov