lims_combined_synopsis .pdf

COMBINED SYNOPSIS / SOLICITATION

(1) Action Code: Combined Synopsis/Solicitation

(2) Date: November 20

(3) Year: 2019

(4) Contracting Office Zip Code: 20892

(5) Classification Code: 7030

(6) Contracting Office Address:

6701 Rockledge Drive Rockledge II Bethesda, MD 20892

(7) Subject/Title: LIMS Annual License Subscription for NIAMS IRP and Genomics Technology Section.

(8) Proposed Solicitation Number: 75N92020Q0011

(9) Closing Response Date: November 30, 2019

(10) Contact Point(s): Tahir Seeba

(11) Contract Award and Solicitation Number: TBD

(12) Contract Award Dollar Amount: TBD

(13) Contract Line Item Number(s): See 1449

(14) Contractor Award Date: TBD

(15) Contractor Name: TBD

(16) Description:

(i) This is a combined synopsis/solicitation for commercial items prepared in accordance with the format in Subpart 12.6 as supplemented with additional information included in this notice. This announcement constitutes the only solicitation; quotes are being requested and a written solicitation will not be issued.

Background:

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) is one of the nation’s premier research institutions in the areas of clinical research in muscle, skin, bone, autoimmune and rheumatic diseases. Investigators within the Intramural Research Program of NIAMS rely on the Genomics Technology Section to meet the increasing demands of research, by providing different tools the study these diseases.

NGS (Next Generation Sequencing) data is a critical component of the research conducted by NIAMS IRP scientists, and there has been a steady increase in its use throughout the institute. Prior to implementing Illumina BaseSpace Clarity LIMS, the workflow for submitting sequencing samples was a manual and tedious process that could not effectively support and track the number of samples submitted. The acquisition of the BaseSpace Clarity LIMS software on 12/2018 was only solution to provide full integration with Illumina sequencers. The software has satisfied the needs for end-to-end workflow tracking and integration, time-saving automation, preconfigured workflows, management reporting functionality, support for regulatory compliance, and role-based interfaces designed to match the needs of individuals in the lab.

Objectives:

To continue supporting NIAMS IRP research efforts with cutting-edge technology that meet the increasing demands in genomics research, we are seeking an annual LIMS software license subscription. This software will be used by multiple labs for the submission of sequencing samples and to track sequencing data sets.

(ii) The solicitation number is 75N92020Q0011 and the solicitation is issued as request for quotation (RFQ).

(iii) The solicitation document, the incorporated provisions and clauses are those in effect through Federal Acquisition Circular (FAC) 2020-01 effective November 12, 2019.

(iv) The associated NAICS code 511210 Software Publishers and the small business size standard $38.5 million. The acquisition is being conducted in accordance with the procedures of FAR Part 12 and FAR Part 13.

(v) The Scope:

This effort is to provide a fully operational Laboratory Information Management System Software Subscription. The installed system software must be capable of performing:

- Automate sample preparation, submission, scheduling and run a workflow to the fullest extent possible

- Provide an online system to submit samples for processing

- Provide a consolidated repository for NGS Sample Meta-data

- Improve the quality of NGS Sample meta-data provided for sequencing

- Automate initial analysis pipeline – conversion to fastq, alignment

- Provide Dashboards, Reporting, and Search capabilities

(vi) The Contractor Requirements are listed below:

The Contractor shall provide the following Illumina SpaceBase Clarity LIMS Software Subscription to Brand Name or Equal Specifications:

Software Requirement:

The LIMS software shall:

- Support compliance with eSignature, audit trails, reagent, and lot tracking, and privacy and security controls.

- Reduce time with straightforward implementation, reporting, preconfigured workflows for standard instruments, and quality control features that flag poor-quality samples.

- Provide accuracy with automation and built-in business logic and error checking

- Manage complexity and change with integrations and workflows for sequencing and the ability to create new workflows when needed.

- Accommodate increased sample volumes with different editions and on-site or cloud-based implementations.

- Enable thorough customization to laboratory environment through the use of the application programming interface (API)

LIMS Software Specifications:

The LIMS software shall perform the following functions:

Sample tracking, Sample sheet generation, Single user access, Visual pooling and adapter assignment, Community forum, Reagents, and controls tracking, QC tracking, Collaboration portal, Overview Dashboards, preconfigured workflows, lab operation reports, Instrument tracking , Application Programming Interface

(API).

LIMS software Integration:

- The system must be web-based, accessible via the internal NIH network

- The system must be installed on-premise, on NIAMS (and NIH where applicable) supported infrastructure.

- The system must integrate with NIAMS existing Illumina sequencers (Illumina MiSeq, NovaSeq 6000, and NextSeq 550), and QC instrumentation must be provided.

- The software must operate on CentOS 6 operating system.

Contract Requirement:

The Contractor shall provide:

- System training, including Role-Based LIMS User training, API training, Toolkit training, and Reporting Module training, must be provided free of charge.

- Consulting Services for LIMS, API, Toolkit, Data Model, and Reporting Module must be provided.

- User Guides/Manuals

- Free software updates

- Software Customer Support Services

(vii) Period of Performance:

Base Year : 12/09/2019 - 12/08/2020 Option Year 1: 12/09/2020 - 12/08/2021 Option Year 2: 12/09/2021 - 12/08/2022

Deliverables:

The Contractor shall set up, install and configure the LIMS software on NIAMS infrastructure system, and verify the system functionality before the contract effective date.

(viii) The provision at FAR clause 52.212-1, Instructions to Offerors –

Commercial Items, applies to this acquisition.

(ix) The provision at FAR clause 52.212-2, Evaluation – Commercial Items, is applicable. The award will be made to the contractor providing the most advantageous quote to the Government, technical factors and price considered. Technical factors are weighted higher than price.

Technical Factors:

1: Ability to provide the required software as described in section 16.(vi)

(x) FAR clause 52.212-3, Offeror Representations and Certifications –

Commercial Items, is applicable. An offeror shall complete only paragraphs (b) of this provision if the offeror has completed the annual representations and certificates electronically via http://www.acquisition.gov. If an offeror has not completed the annual representations and certifications electronically at the System for Award Management (SAM) website, the offeror shall complete only paragraphs

(c) through (p) of this provision.

(xi) FAR clause at 52.212-4, Contract Terms and Conditions – Commercial

Items, applies to this acquisition.

(xii) FAR clause at 52.212-5, Contract Terms and Conditions Required to Implement Statutes or Executive Orders – Commercial Items, applies to this acquisition. Including the following Clauses and Prohibitions:

i. 52.219-28, Post Award Small Business Program

Representation

ii. 52.222-19, Child Labor—Cooperation with Authorities and

Remedies 52.222-21, Prohibition of Segregated Facilities

iii. 52.222-26, Equal Opportunity

iv. 52.222-36, Equal Opportunity for Workers with Disabilities

v. 52.222-50 Combating Trafficking in Persons

vi. 52.225-13, Restrictions on Certain Foreign Purchases

vii. 52.223-18, Encouraging Contractor Policies to Ban Text

Messaging while Driving

viii. 52.225-1, Buy American--Supplies

Additional Clauses:

i. 52.232-39, Unenforceability of Unauthorized Obligations

ii. 52.211-6, Brand Name or Equal

iii. 52.217-9, Option to Extend the Term of the Contract

(xiii) Additional contract requirements: None

(xiv) The Defense Priorities and Allocations System (DPAS) and assigned rating, is applicable.

(xv) Offers shall be submitted via the FedConnect web portal (www.fedconnect.net). The due date for receipt of offers is 3:00 PM Eastern Time on November 30, 2019.

(xvi) Contracting Office Point Of Contact:

Tahir Seeba

NIH-NLBI

6701 Rockledge drive, Rockledge II, RM 6132

Bethesda, MD 20814 Email: tahir.seeba@nih.gov

(17) Place of Contract Performance:

Laboratory of Muscle Stem Cells and Gene Regulation Building 50 / Room 1342.

Bethesda, MD 20886

(18) Set-aside Status: N/A mailto:tahir.seeba@nih.gov mailto:tahir.seeba@nih.gov