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This document is a Statement of Need (SON) for the procurement of one (1) Brand Name or Equal BD High Throughput Sampler for a government-owned BD LSRFortessa Flow Cytometer (Serial# R647117700197) used by the Lymphoid Malignancies Branch (LyMB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH).

The SON specifies that the required High Throughput Sampler (HTS) unit must be compatible with the existing BD LSRFortessa Flow Cytometer, have automated 96-well or 384-well plate sample acquisition capabilities, adjustable sample mixing settings, and direct communication with the BD FACSDiva software. The HTS unit must include installation, calibration, testing, and a 1-year warranty. Delivery is required within 8 weeks of contract award, with installation to be completed within 14 calendar days. Final inspection and acceptance will be conducted by the NCI Technical Point of Contact. No training is required. Payment will be made in full after successful delivery, installation, and acceptance of the equipment.

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STATEMENT OF NEED (SON)

75N91024Q00116 Page 1 of 2 National Institutes of Health / National Cancer Institute / Office of Acquisitions

1.0 TITLE

Procurement of One (1) Brand Name or Equal BD High Throughput Sampler for government-owned BD LSRFortessa (Serial# R647117700197)

2.0 BACKGROUND

The Lymphoid Malignancies Branch (LyMB), Center for Cancer Research (CCR), National Cancer Institute (NCI), National Institutes of Health (NIH) uses a government-owned BD LSRFortessa Flow Cytometer (Serial# R647117700197) extensively in support of ongoing cancer research at LyMB, particularly to investigate the pathogenesis of lymphoid malignancies and to identify therapeutic vulnerabilities in B-cell lymphoma.

The government-owned BD LSRFortessa Flow Cytometer (Serial# R647117700197) only has single tube loading capability. The LyMB would like to expand these flow cytometer’s capacity by adding a High Throughput Sampler (HTS) unit on this system. With the HTS, samples loaded via single tubes are combined in 96-well (or 384-well) plates, and the HTS unit then automatically delivers samples to the flow cytometer. Sample processing in well-plates is more efficient and improves analytical performance.

To meet this increased demand, LyMB seeks a High Throughput Sampler that is compatible with its existing BD LSRFortessa Flow Cytometer. Therefore, LyMB requires one (1) Brand Name or Equal BD High Throughput Sampler.

3.0 TYPE OF ORDER

This shall be a Firm Fixed-Price Purchase Order.

4.0 SPECIAL ORDER REQUIREMENTS

4.1 PRODUCT FEATURES/SALIENT CHARACTERISTICS

The following product features/characteristics are required for this requirement:

• The High Throughput Sampler (HTS) unit shall be compatible with government-owned BD LSRFortessa flow cytometer, Serial# R64717700197.

• Automated sample acquisition from 96-well or 384-well plates.

• Adjustable settings for Sample Mixing (volume, speed, and number of mixes)

• The units shall communicate directly with BD FACSDiva software v6.2 or later.

• Shall include installation, calibration, and testing of one (1) HTS unit on BD LSRFortessa flow cytometer.

• One (1) Year Warranty.

4.2 WARRANTY

In addition to the Implied warranty contained in FAR Clause 52.212-4, the Contractor is encouraged to provide express warranties. At a minimum, the Contractor shall provide a 12-month warranty from date of final installation on all equipment and associated items provided under, or as a part of this purchase order. The warranty shall include repair and or replacement of parts, including travel, labor, and materials, at no additional cost to the Government. The warranty shall not exclude or limit the Governments rights for an Implied warranty as established in the terms and conditions of clause 52.212-4.

STATEMENT OF NEED (SON)

75N91024Q00116 Page 2 of 2 National Institutes of Health / National Cancer Institute / Office of Acquisitions

4.3 DELIVERY / INSTALLATION

Delivery shall be within eight (8) weeks of the purchase order award. All shipping/handling (including FOB Destination) and delivery/installation fees shall be included in the quote. Upon delivery, the Contractor shall notify the respective NCI Technical Point of Contact to schedule installation dates and times. Installation shall occur within fourteen (14) calendar days of delivery and shall be performed by, or under the direct supervision of, a certified operator.

The contractor shall deliver and install the equipment at the following address:

Lymphoid Malignancies Branch, National Institutes of Health/NCI 9000 Rockville Pike Bethesda, MD 20892 Technical Point of Contact: [to be provided upon award]

4.3.1 DELIVERY GUIDANCE

The Contractors shall communicate and follow instructions from the Technical Point of Contact (TPOC) to coordinate delivery and installation.

The Contractor shall direct all courier and delivery services – including those not operated by the Contractor (e.g. FedEx, USPS, UPS) – to follow the instructions in this section.

All companies delivering to the NIH main campus must comply with Commercial Vehicle Inspection Facility (CVIF) access procedures. Upon arrival, the CVIF will provide a list of buildings and loading docks to delivery personnel.

Deliveries will be logged in at the loading dock, and the loading dock contractor or Government personnel will attempt to contact the TPOC listed on the package. In the event that the TPOC is unable to accept the package, the delivery shall not be left at the loading dock station. The delivery must be returned to the Contractor, and the Contractor must coordinate with the TPOC to deliver on another date at no additional cost.

Deliveries can only be made between 6:00 a.m. and 4:00 p.m. EST, Monday – Friday, excluding federal holidays.

4.4 INSPECTION AND ACCEPTANCE

Pursuant to FAR Clause 52.212-4, all items to be delivered in relation to this Purchase Order are subject to final inspection and acceptance by an authorized representative of the Government. The authorized representative of the Government is the TPOC who is responsible for inspection and acceptance of all services, materials, or supplies to be provided by the Contractor.

4.5 TRAINING

Training is not required for this equipment.

5.0 PAYMENT

Payment shall be made in full after the successful delivery, installation, and acceptance of equipment by the NCI Technical Point of Contact (TPOC). Payment authorization requires submission and approval of invoices to the NCI TPOC and NIH OFM.

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