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This document provides an amendment to a Small Business Innovation Research (SBIR) solicitation issued by the National Institutes of Health's National Cancer Institute on behalf of the Advanced Research Projects Agency for Health (ARPA-H). The amendment includes responses to questions from prospective offerors. Key details include: revised page limit guidance for Phase I and Phase II proposals, instructions to combine Phase I and Phase II technical and business proposals into a single attachment for Fast-Track submissions, and corrections to titles in Phase I proposal templates. Resumes and CVs for key personnel may be attached but do not count against page limits. The proposal due date remains July 3, 2023 at 5:00PM EDT.

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Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

(a) By completing items 8 and 15, and returning or (c) By separate letter or electronic communication which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by letter or electronic communication, provided each letter or electronic communication makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.

E. IMPORTANT: Contractor is not is required to sign this document and return copies to the issuing office.

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT 1. CONTRACT ID CODE

3. EFFECTIVE DATE 4. REQUISITION/PURCHASE REQUISITION NUMBER 5. PROJECT NUMBER (If applicable)

7. ADMINISTERED BY (If other than Item 6) CODE

STANDARD FORM 30 (REV. 11/2016)

Prescribed by GSA FAR (48 CFR) 53.243

FACILITY CODE

9A. AMENDMENT OF SOLICITATION NUMBER

10A. MODIFICATION OF CONTRACT/ORDER NUMBER

10B. DATED (SEE ITEM 13)

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers is extended. is not extended.

12. ACCOUNTING AND APPROPRIATION DATA (If required) copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted;

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS.

IT MODIFIES THE CONTRACT/ORDER NUMBER AS DESCRIBED IN ITEM 14.

CHECK ONE A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER

NUMBER IN ITEM 10A.

B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES (such as changes in paying office, appropriation data, etc.) SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER (Specify type of modification and authority)

15C. DATE SIGNED

15A. NAME AND TITLE OF SIGNER (Type or print)

16C. DATE SIGNED

PAGE OF PAGES

6. ISSUED BY CODE

8. NAME AND ADDRESS OF CONTRACTOR (Number, street, county, State and ZIP Code) (X)

CODE

15B. CONTRACTOR/OFFEROR

(Signature of person authorized to sign)

16B. UNITED STATES OF AMERICA

(Signature of Contracting Officer)

Previous edition unusable

2. AMENDMENT/MODIFICATION NUMBER

16A. NAME AND TITLE OF CONTRACTING OFFICER (Type or print)

Mary Muir Contracting Officer

14. DESCRIPTION OF AMENDMENT/MODIFICATION (Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

The purpose of this amendment is to additional

Offerors are required to acknowledge each Solicitation Amendment by including each Standard Form 30 (SF-30) signed by your organization’s signature authority and submitted with your proposal.

Proposal Due Date: July 3, 2023, 5:00PM EDT (Unchanged)

Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

N/A National Institutes of Health National Cancer Institute Office of Acquisitions 9609 Medical Center Dr., MSC 9705 Bethesda, MD 20892-9705

N/A

75N91023R00041

N/A

06/ /2023

9B. DATED (SEE ITEM 11)

06/1 /2023

6/ /2023

Mary E. Muir -S Digitally signed by Mary E. Muir - S Date: 2023.06.22 14:27:23 -04'00'

Solicitation 75N91023R00041 Amendment #3 – Solicitation Question and Responses 2

ARPA-H SBIR Solicitation 75N91023R00041 - Amendment #3

Sollicitation Questions and Responses

Please see the following questions and answers:

Q1: The response to question #28 in Amendment #2, “What are the requirements for proposals regarding: font, font size, and margins?,” is revised as follows:

A1: There aren’t any specific requirements for font, font size, and margins. However, there are page limit requirements for Phase I and II applications. The page limits are in the application templates

(Appendices A - D of the solicitation) for each Phase. Defined page limits only exclude the required letters for Phase I and the required resumes and letters for Phase II. Letters and Resumes should be attached to the Technical Proposal. See updated Phase I and II application templates.

Q2: For Fast-Track submission, how should I combine the Phase 1 and Phase 2 Technical and Business proposals when submitting to the portal?

A2: Please combine Phase I and II and upload as a single attachment in the portal, if possible. If you have already submitted your Fast-Track submission a different way, you do not need to resubmit.

Q3: I noticed the title in the word document for Appendix B - Phase I Business Proposal has "PHASE II

BUSINESS PROPOSAL." I just wanted to double check this a typo and I have the correct form.

A3: The title in both APPENDIX A - Phase I Technical Proposal and APPENDIX B - Phase I Business

Proposal have been updated to reflect “PHASE I”. See updated Phase I application templates.

Q4: Should I include biosketch or CV for key personnel in the application? If so, where is the most appropriate place to attach those?

A4: Resumes/CVs are only for key personnel and do not count towards the defined page limits.

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