Amendment 1 36C26123Q0675 0001.pdf

5. PROJECT NUMBER (if applicable)

CODE 7. ADMINISTERED BY

2. AMENDMENT/MODIFICATION NUMBER

CODE

6. ISSUED BY

8. NAME AND ADDRESS OF CONTRACTOR

4. REQUISITION/PURCHASE REQ. NUMBER 3. EFFECTIVE DATE

9A. AMENDMENT OF SOLICITATION NUMBER

9B. DATED

PAGE OF PAGES

10A. MODIFICATION OF CONTRACT/ORDER NUMBER

10B. DATED

BPA NO. 1. CONTRACT ID CODE

FACILITY CODE CODE

Offers must acknowledge receipt of this amendment prior to the hour and date specified in the solicitation or as amended, by one of the following methods:

The above numbered solicitation is amended as set forth in Item 14. The hour and date specified for receipt of Offers

E. IMPORTANT:

is extended,

(a) By completing Items 8 and 15, and returning __________ copies of the amendment; (b) By acknowledging receipt of this amendment on each copy of the offer submitted; or (c) By separate letter or electronic communication which includes a reference to the solicitation and amendment numbers. FAILURE OF YOUR ACKNOWLEDGMENT TO BE RECEIVED AT THE PLACE DESIGNATED FOR THE RECEIPT OF OFFERS PRIOR TO THE HOUR AND DATE SPECIFIED MAY is not extended.

12. ACCOUNTING AND APPROPRIATION DATA

(REV. 11/2016)

is required to sign this document and return ___________ copies to the issuing office. is not, A. THIS CHANGE ORDER IS ISSUED PURSUANT TO: (Specify authority) THE CHANGES SET FORTH IN ITEM 14 ARE MADE IN THE CONTRACT ORDER NO. IN ITEM 10A.

15C. DATE SIGNED

B. THE ABOVE NUMBERED CONTRACT/ORDER IS MODIFIED TO REFLECT THE ADMINISTRATIVE CHANGES SET FORTH IN ITEM 14, PURSUANT TO THE AUTHORITY OF FAR 43.103(b).

RESULT IN REJECTION OF YOUR OFFER. If by virtue of this amendment you desire to change an offer already submitted, such change may be made by letter or electronic communication, provided each letter or electronic communication makes reference to the solicitation and this amendment, and is received prior to the opening hour and date specified.

C. THIS SUPPLEMENTAL AGREEMENT IS ENTERED INTO PURSUANT TO AUTHORITY OF:

D. OTHER

Contractor

16C. DATE SIGNED

14. DESCRIPTION OF AMENDMENT/MODIFICATION

16B. UNITED STATES OF AMERICA

Except as provided herein, all terms and conditions of the document referenced in Item 9A or 10A, as heretofore changed, remains unchanged and in full force and effect.

15A. NAME AND TITLE OF SIGNER 16A. NAME AND TITLE OF CONTRACTING OFFICER

15B. CONTRACTOR/OFFEROR

STANDARD FORM 30 PREVIOUS EDITION NOT USABLE

Prescribed by GSA - FAR (48 CFR) 53.243

(Type or print) (Type or print)

(Organized by UCF section headings, including solicitation/contract subject matter where feasible.)

(Number, street, county, State and ZIP Code)

(If other than Item 6)

(Specify type of modification and authority)

(such as changes in paying office, appropriation date, etc.)

(If required)

(SEE ITEM 11)

(SEE ITEM 13)

(X)

CHECK

ONE

13. THIS ITEM APPLIES ONLY TO MODIFICATIONS OF CONTRACTS/ORDERS,

IT MODIFIES THE CONTRACT/ORDER NO. AS DESCRIBED IN ITEM 14.

11. THIS ITEM ONLY APPLIES TO AMENDMENTS OF SOLICITATIONS

AMENDMENT OF SOLICITATION/MODIFICATION OF CONTRACT

(Signature of person authorized to sign) (Signature of Contracting Officer)

1 3

10-12-2023

640-24-1-044-0002

None

612MCP

Department of Veterans Affairs

Network Contracting Office (NCO) 21 3237 Peacekeeper Way, Bldg 200 Suite 204 McClellan Park CA 95652

612MCP

Department of Veterans Affairs

Network Contracting Office (NCO) 21 3237 Peacekeeper Way, Bldg 200 Suite 204 McClellan CA 95652

To all Offerors/Bidders

36C26123Q0675

09-29-2023

X

X

** HOUR & DATE for Receipt of Offers is EXTENDED to: 10/17/2023 at 10:00 am PST.

X 1

The purpose of this amendment is to include the Question and Answer (QA) response below and extends the solicitation response due date to October 17, 2023, at 10:00 am PST.

All other terms and conditions remain unchanged.

Tim Smith Contracting Officer

1. 0001 SLIDES PER TISSUE BLOCK, ROUTINE H&E STAIN—is there a standardized tissue thickness that is required for samples?

VA Response - Yes, 5 microns for all samples except Neuro/brains, microtomy will be at 7 microns.

2. 0004 SPECIAL HISTOCHEMICAL STAINS, STANDARD CPT 88313—Will you please advise what special stains would most likely be required for the work order? Do you have preferred manufacturer(s) of reagents? Are optimized and/or validated protocols available?

VA Response – GMS, PAS, PAS/d, Reticulum, Acid Fast Bacteria (AFB), Iron(FE), Gram (positive, negative), Warthin-Starry, Steiner, Elastic (EVG), Alcian-Blue, Papanicolaou (PAP), Trichrome, Congo Red, Von Kossa, Mucicarmine, Giemsa.

3. 0005 IMMUNOHISTOCHEMICAL STAINS CPT 88342—1) Which markers? 2) Any required manufacturer of antibodies? 3) Any product/catalog# of antibodies as examples? Will you provide optimized and/or validated protocols with the list of reagents needed? (along with manufacturer and product/catalog# of reagents if practical)? Will CPT 88342 include any immunocytochemistry samples?

VA Response - ALK, Arginase1, BCL1 (Cyclin D1), BCL2, BCL6,C4d,CAIX,Calcitonin,Calretinin,CD10,CD117 (c-kit), CD2, CD7, CD138,CD15,CD163,CD1a,CD20,CD21,CD23,CD3,CD30,CD31,CD34,CD4,CD43,CD4 5(LCA),CD5,CD68,CD79a,CD8,CDX2,CEA,Chromogranin A, CK20,CK 5/6, CK7,CMV,D2-40,Desmin,DOG1,EA(Ber-EP4),EMA,ERA(MOX-31), ERG, Factor 13a, GATA3,GFAP, Glypican-3, H. Pylori, Hepatocyte (HepPar1), HHV8, HMB45, HMW cytokeratin, HSV (type1), Kappa (protein), Ki67, Lambda (protein), Melan A, MSIx4

(MLH1, MSH2, MSH6, PMS2), MUM1, MYELIN BASIC PROTEIN,

MYELOPEROXIDASE, NEUROFILAMENT, NKX3.1, P16,P40,P53, P63, Pan-Keratin, PAX5, PAS8, PIN2 (P504S + p63), PRAME, PSA, PSAP, ROS1,S100, SMA, SOX10, SOX11, STAT6, Synaptophysin, Thyroglobulin, TTF-1, Vimentin, WT-1, brafv600e, ISH prob Kappa, ISH probe Lambda, ISH probe EBER1.

The lab that the VA is contracting to do this work, should have validated protocols themselves and should be able to get its own manufactures of antibodies, and the lab should be accredited. This lab should provide its own positive/negative controls. Here at VAPA we use Roche/Ventana equipment for testing. Most of our antibodies are pre-fills from Roche, which means we order without having to dilute/ready to use.

4. 0006 ANTIBODY STAINS CPT 88344-Would you please provide what antibodies you would need: 1) marker 2) manufacturer of antibodies 3) product/catalog# of antibodies if practical? Can you provide optimized and/or validated protocols with the reagents needed along with the manufacturer and product/catalog#?

VA Response – See response to question 3.

5. Is there specific slide labeling that is required for this work order? Can you please provide what information you require on the slide label?

VA Response – Yes, all slides will be printed or hand written, see below.

23S- 1623 B

VAPA HCS

Palo Alto, CA