36C24E25Q0034_1.docx
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- Solicitation number
- 36C24E25Q0034
About this file
This is a Special Notice for a sole-source procurement of specialized genetic sequencing services for the Veterans Health Administration (VA). The Regional Procurement Office (RPO) - East intends to negotiate directly with Novogene Corporation, Inc. for a VA-funded research study titled "Impact of Obesity on Brain Immune Response and Cognition" at the Minneapolis VA Health Care System. The primary objectives are to analyze mouse brain samples from wild-type and Alzheimer's Disease (AD) mice, investigating neuroinflammation mechanisms and potential new AD treatment targets, with a focus on high-fat diet and environmental toxin exposure impacts.
Novogene will provide comprehensive genetic sequencing services, including RNA processing, library preparation, sequencing, and data output generation. The VA laboratory expects to send 4 to 20 samples annually, with Novogene responsible for high-accuracy, reproducible quantitative analysis across various tissue types and sequencing modalities. The solicitation (36C24E25Q0034) is open for capability statements until March 26, 2025, at 11:59 AM EST, submitted to Contracting Officer Millicent Covert via email. While the procurement is intended as a sole-source award, the VA will consider alternative qualified sources, with the final determination of competition at the government's discretion.
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Special Notice Special Notice
| SUBJECT* |
| Specialized Genetic Sequencing Services (VA Research Study) |
GENERAL INFORMATION
| CONTRACTING OFFICE’S ZIP CODE* |
| 15215-1802 |
| SOLICITATION NUMBER* |
| 36C24E25Q0034 |
| RESPONSE DATE/TIME/ZONE |
| 03-26-2025 11:59 EASTERN TIME, NEW YORK, USA |
| ARCHIVE |
| 60 DAYS AFTER THE RESPONSE DATE |
| RECOVERY ACT FUNDS |
| N |
| PRODUCT SERVICE CODE* |
| AN11 |
| NAICS CODE* |
| 541715 |
| CONTRACTING OFFICE ADDRESS |
| Veterans Health Administration |
Regional Procurement Office East Building 32 Suite 1A1111 1010 Delafield Road Pittsburgh PA 15215-1802
POINT OF CONTACT*
Contracting Officer Ms. Millicent Covert millicent.covert@va.gov (Calls shall not be taken)
ADDITIONAL INFORMATION
AGENCY’S URL
URL DESCRIPTION
AGENCY CONTACT’S EMAIL ADDRESS
EMAIL DESCRIPTION
DESCRIPTION
Regional Procurement Office (RPO) - East intends to negotiate on a sole source basis, pursuant to FAR 6.302-1, with Novogene Corporation, Inc., for specialized genetic sequencing services for the Research Department at the Minneapolis VA Health Care System. These services are required for the VA-funded research study “Impact of Obesity on Brain Immune Response and Cognition”.
The objective of the study is to determine key features that differentiate the spatial configuration and expression profile of mouse brain from either WT or Alzheimer’s Disease expressing (AD) mice with confounding factors such as high-fat diet or environmental toxin exposure. We may identify new targets for AD treatment by identifying two new mechanisms of disease progression: 1) Enhanced neuroinflammation due to exacerbation of inflammatory factors due to high-fat diet or environmental toxin exposure in the AD background. 2) Identification of new disease mechanisms may improve the care of Veterans with AD, high-fat diet, and/or environmental toxin exposure thereby decreasing costs for the Veterans Affairs Health Care System.
Highly experienced in providing data from large-scale sequencing projects, Novogene has been involved in previous studies directly related to the current study. To ensure consistent support, data readability and compatibility, continuation of Novogene’s services is crucial to the study’s successful outcome.
Novogene (contractor/contractor laboratory) shall:
· Process, sequence, and quantify the RNA from samples on a massive scale with high-accuracy, dependability, and reproducibility.
· Perform RNA library preparation, sequence the RNA, and prepare a data output including sequence identity and quantity for all samples.
· Provide start-to-finish advanced genetic sequencing and quantitation services tailored to the analysis of single-cells.
· Provide accurate and reproducible quantitative results for a variety of tissue types and sequencing modalities.
The VA laboratory anticipates sending 4 to 20 samples per year depending on experimental outcomes.
This is a notice of intent and is not a request for competitive quotes; however, any responsible source that believes it is qualified to meet this unique need may submit a capability statement to the contracting office no later than Wednesday, March 26, 2025, 11:59 AM EST. Interest/capability statements may be sent to Millicent Covert, Contracting Officer, at millicent.covert@va.gov. No telephone responses will be accepted. A determination not to compete the proposed requirement based upon the responses to this notice is solely within the discretion of the Government.
| *= Required Field |
| Special Notice |
Special Notice
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