36C24E24Q0139_1.docx
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- Solicitation number
- 36C24E24Q0139
About this file
This document is an Amendment to a Previous Combined Solicitation for DNA Methylation and Genome Wide Association assays to evaluate changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Study. The solicitation is issued as a Request for Quote (RFQ) by the Department of Veterans Affairs Veterans Health Administration Veterans Integrated Service Network 4 with a response due date of September 27, 2024 at 9:00 AM EST.
The Government is seeking a one-year Purchase Order Contract to provide services for 191 samples of Epigenetic Markers (DNA Methylation) for 935,000 CpG sites using the EPICv2 array, 191 PaxGene DNA Extractions, 102 Genome Wide Association Studies (GWAS), and 102 Sample Processings. The NAICS code is 541715 - Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology). There is no incumbent contractor - this is a new requirement. Pricing, technical capabilities, and past performance will be evaluated. Award will be made to the most advantageous response.
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Amendment to a Previous Combined Solicitation
Amendment to a Previous Combined Solicitation
| SUBJECT* |
| DNA Methylation & Genome Wide Association assays for evaluating changes in Epigenetic Aging for Veterans with HIV who participated in a Telehealth-delivered High-Intensity Exercise Program |
GENERAL INFORMATION
| CONTRACTING OFFICE’S ZIP CODE* |
| 15215-1802 |
| SOLICITATION NUMBER* |
| 36C24E24Q0139 |
| RESPONSE DATE/TIME/ZONE |
| 09-27-2024 9:00 EASTERN TIME, NEW YORK, USA |
| ARCHIVE |
| 5 DAYS AFTER THE RESPONSE DATE |
| RECOVERY ACT FUNDS |
| N |
SET-ASIDE
| PRODUCT SERVICE CODE* |
| AN12 |
| NAICS CODE* |
| 541715 |
| CONTRACTING OFFICE ADDRESS |
| Veterans Health Administration |
Regional Procurement Office East Building 32 Suite 1A1111 1010 Delafield Road Pittsburgh PA 15215-1802
POINT OF CONTACT*
Contract Specialist Karly Gabrysiak Karly.gabrysiak@va.gov E-Mail only
PLACE OF PERFORMANCE
ADDRESS
POSTAL CODE
| COUNTRY |
| USA |
ADDITIONAL INFORMATION
AGENCY’S URL
URL DESCRIPTION
AGENCY CONTACT’S EMAIL ADDRESS
EMAIL DESCRIPTION
DESCRIPTION
Amendment 1 – Answer Vendor Questions for Solicitation 36C24E24Q0139.
Question 1: “We are performing independent research on the Combined Synopsis/Solicitation (36C24E24Q0139). We would like to know if this is a brand new contract OR if there is (was) an incumbent performing these services. If not brand new, could you please provide the current / previous contract number? Appreciate any insight you can provide.”
Answer to Question 1: This is new and there is no incumbent performing these services for the Requesting Activity for VA Portland Health Care System.
Questions 2-8 were sent in together* Question 2: We utilize a custom EPIC V2 array with additional information. Would that array be appropriate to use for this project or would the standard EPIC V2 array be more appropriate?
Answer to Question 2: The standard version of EPIC V2 array is what is planned for use.
Question 3: Are the 102 samples to be used for GWAS a subset of the 191 or a separate cohort? In either case, can you help me better understand the expectation for sample processing in Item Number 4?
Answer to Question 3: The 102 is a subset of the 191. The sample processing is any required processing to do the required assays only.
Question 4: Is there an expectation to use genotyping arrays for the GWAS? If so, is there a preference or would one of the arrays we use for MVP be appropriate?
Answer to Question 4: The GWAS array genotyping is part of the study. The MVP array is fine, as well as the Illumina GSA array.
Question 5: Would PacBio long read sequencing be considered for the GWAS?
Answer to Question 5: No, only the GWAS array for genotyping. See (3) above.
Question 6: What should be the disposition of the samples once the assays are finished?
Answer to Question 6: If possible, would be best to return to us.
Question 7: Is there an expectation for data analysis beyond providing the raw data?
Answer to Question 7: No data analysis needed.
Question 8: What are the requirements for data delivery?
Answer Question 8: Encrypted and sent via secure FTP. Upon award this will be facilitated.
| *= Required Field |
| Amendment to a Previous Combined Solicitation |
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Amendment to a Previous Combined Solicitation
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