36C24125Q0893.docx
DOCX document 27 KB Posted
- Attached to
- 6640--RNA Scope Federal contract opportunity
- Solicitation number
- 36C24125Q0893
About this file
This document is a Presolicitation Notice from the Department of Veterans Affairs for an RNA Scope contract to be awarded solely to BIO-TECHNE SALES CORPORATION at the Providence VA Medical Center. The procurement is for multiplex RNA in situ hybridization (ISH) assays, probes, reagents, and controls to support neuropathology research on protein synthesis, neurotransmitter release, and cellular biosynthesis processes.
The solicitation (36C24125Q0893) includes specific requirements for RNA Scope products, such as probes for genes like EIF4H, STXBP5, UCK2, and PSEN2, along with negative and positive control probes. The contract will utilize a Leica Bond RX system for human frozen tissue samples, with a total of 2-3 units of each specified product. The sole source procurement is authorized under FAR 6.302.1-1, with a response deadline of September 26, 2025, at 10:00 AM EST. The contract falls under NAICS code 334516 with a size standard of 1,000 employees and Product Service Code 6640.
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Text version
Presolicitation Notice Presolicitation Notice
| SUBJECT* |
| RNA Scope |
GENERAL INFORMATION
| CONTRACTING OFFICE’S ZIP CODE* |
| 04330 |
| SOLICITATION NUMBER* |
| 36C24125Q0893 |
| RESPONSE DATE/TIME/ZONE |
| 09-26-2025 10:00 EASTERN TIME, NEW YORK, USA |
| ARCHIVE |
| 60 DAYS AFTER THE RESPONSE DATE |
SET-ASIDE
| PRODUCT SERVICE CODE* |
| 6640 |
| NAICS CODE* |
| 334516 |
| PLACE OF PERFORMANCE |
| Department of Veterans Affairs |
Providence VA Medical Center
830 Chalkstone Ave.
Providence RI
| POSTAL CODE |
| 02908 |
| COUNTRY |
| USA |
CONTACT INFORMATION
| CONTRACTING OFFICE ADDRESS |
| Department of Veterans Affairs |
Network Contracting Office 1 (NCO 1) Contracting Officer (90C) 1 VA Center Augusta ME 04330
POINT OF CONTACT*
Contract Specialist Andrew Simard andrew.simard@va.gov Email Only
ADDITIONAL INFORMATION
AGENCY’S URL
URL DESCRIPTION
| AGENCY CONTACT’S EMAIL ADDRESS |
| andrew.simard@va.gov |
| EMAIL DESCRIPTION |
| andrew.simard@va.gov |
DESCRIPTION
Pre-Solicitation Notice of intent to award a sole source contract. This is not a solicitation. The Department of Veterans Affairs intends to negotiate a sole source contract with:
BIO-TECHNE SALES CORPORATION
614 MCKINLEY PLACE NE
MINNEAPOLIS, MN 55413-2610
EF7GFHEAB426
This is not a solicitation. The Department of Veterans Affairs intends to award RNA Scope located at the VAMC Providence, RI. BIO-TECHNE SALES CORPORATION is the Exclusive/Sole source vendor specializing in advanced scientific RNA Scope-ISH manufacturing supporting research goals. The contractor will provide the required equipment. Since the intent is to procure this on a sole source basis, no solicitation will be posted to Contracting Opportunities SAM.gov.
The authority for this action is FAR 6.302.1-1 Only One Responsible source and no other supplies or services will satisfy agency requirements.
The NAICS 334516. The size standard is 1,000 employees. The PSC/FSC is 6640.
Interested persons may contact the Contracting Specialist by email at andrew.simard@va.gov regarding this procurement.
The determination to conduct a competitive procurement based on responses to this notice is solely within the discretion of the Contracting Officer.
Response must be received by 09/26/2025 NLT 10:00am EST.
STATEMENT OF WORK
The requirement is for multiplex RNA ISH (in situ hybridization) assays, probes, associated reagents and positive/negative controls to conduct RNA ISH for our current CTE and AD neuropathology studies looking at protein synthesis at the level of mRNA utilization, neurotransmitter release and synaptic vesicle fusion, DNA and RNA biosynthesis, and regulation of amyloid precursor protein.
| Instrument Platform |
| Leica Bond RX system |
| Species |
| Human |
| Tissue type |
| Frozen |
| ACD/Bio-techne Vendor Contact |
| Suzanne Mertens (Suzanne.Mertens@bio-techne.com) |
Required Items:
| Catalog# |
| Product Description |
| Quantity |
| 1694368-C1 |
| RNAscope™ 2.5 LS Probe - Hs-EIF4H-C1,Homo sapiens eukaryotic |
translation initiation factor 4H (EIF4H), transcript variant 1, mRNA
| 1660708-C2 |
| RNAscope™ 2.5 LS Probe - Hs-STXBP5-C2,Homo sapiens syntaxin binding protein 5 (STXBP5), transcript variant 1, mRNA |
| 2 |
| 434858-C3 |
| RNAscope™ 2.5 LS Probe - Hs-UCK2-C3 - Homo sapiens uridinecytidine kinase 2 (UCK2) mRNA |
| 2 |
| 320878 |
| RNAscope™ 3-plex LS Multiplex Negative Control Probe - |
RNAscope™ 3-plex LS Multiplex Negative control probe DapB (of Bacillus subtilis strain) for RNAscope™ LS 2.5 Multiplex Fluorescent Assay.
| 320868 |
| RNAscope™ LS 2.5 3-plex Positive Control Probe - Hs - |
RNAscope™ LS 2.5 Human positive control probe for RNAscope™ LS 2.5 Multiplex Fluorescent Assay- Polr2a (C1 channel) and PPIB (C2 channel), UBC (C3 channel) In terms of relative expression levels,UBC is the highest, PPIB is considered a moderate-high, POLR2A is moderate-to low expressor target.
| 323155 |
| Kit consisting of the RNAscope™ Multiomic CORE Reagents along |
with C1, C2, and C3 Channel Reagents. Allows 3-plex multiomic detection of RNAs and proteins. TSA-conjugated fluororphores must be purchased separately. For 60 slides.
| 807458 |
| RNAscope™ 2.5 LS Probe - Hs-PSEN2 - Homo sapiens presenilin 2 |
(PSEN2) transcript variant 1 mRNA
| 322930 |
| RNAscope™ Multiomic LS CORE Reagents are designed for RNA |
and protein detection up to a total of 6 targets. Each CORE kit provides enough reagents to stain 60 tissue sections. At least one C1 - C6 Channel Reagent kit must also be purchased for detection.
TSA-conjugated fluorophores must be purchased separately. For 60 slides.
| 322935 |
| RNAscope™ Multiomic C1 Channel Reagents must be used with |
the RNAscope Multiomic LS CORE to provide detection in the C1 channel. The kit consists of C1 HRP, TSA Buffer, and HRP Blocker.
For 60 slides.
| *=Required Field |
| Presolicitation Notice |
Presolicitation Notice
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