2_SON and equipment list for AB Sciex Service.doc

STATEMENT OF NEED

1) BACKGROUND INFORMATION

The RTB Protein Chemistry Section (PCS) enables intramural NIAID investigators to use state-of-the-art applications in mass spectrometry, bioinformatics, chromatographic purification and analysis, protein sequencing and spectrophotometric analysis of peptides, proteins and small molecules in their research programs. These analytical activities provide proteomic profiles, protein structural information including post-translational modifications, quality control and quantitative assay development. In addition, our staff is available for advice and consultations. Extensive support is available for expert analysis in analytical chemistry and biochemistry in the context of the biomedical research conducted at the institute.

Mass spectrometry is a powerful analytical technique that is used to identify unknown compounds, to quantify known compounds, and to elucidate the structure and chemical properties of molecules. Detection of compounds can be accomplished with very minute quantities (as little as 10-12 picograms, 10-15 moles for a compound of mass 1000 Daltons). This means that compounds can be identified at very low concentrations in chemically complex mixtures.

The RTB PCS currently provides mass spectrometry services on a daily basis for all NIAID investigators and the Sciex 4000 Q-Trap is an integral part of this effort. This instrument is in use on a daily basis and if it malfunctioned due to lack of maintenance, mechanical or electronic failure the ability of the investigators in the DIR to conduct their research would be severely handicapped. It is for this reason that a Service Agreement is essential from this sole distributor.

2) PURPOSE AND OBJECTIVES OF THE ACQUISITION

The purpose of this acquisition is to provide a maintenance agreement for the above referenced 4000 Q-Trap in order to maintain it in optimal operating condition.

3) CONTRACTOR REQUIREMENTS:

· Parts, labor and travel for remedial repair.

· No charge for planned maintenance visits. There is one planned maintenance visits that will be performed during the plan period

· Software maintenance, technical support and upgrades. Premium content access to SCIEXUniversity and Knowledge base online

· Update installations at the time of scheduled preventive maintenance visits

· Guaranteed priority response time of 2 days after receipt of a service call

· Priority telephone and email access to instrument technical support.

· Unlimited telephone and email support on workdays 8 AM to 10 AM EST, excluding holidays

4) CONTRACTOR SUPPLIED MATERIALS

The Contractor shall provide all necessary parts and equipment necessary to perform remedial repair and planned maintenance of the above equipment.

5) GOVERNMENT FURNISHED MATERIALS

No Government furnished materials are provided under this contract.

6) REPORTING REQUIREMENTS AND DELIVERABLES

Technical support, software upgrades, and remedial repair as needed, and one annual planed maintenance.

7) INSPECTION AND ACCEPTANCE

a) All work will be inspected and approve by Dr. Glenn Nardone, Protein Chemistry Section, RTB at the completion of any repairs and at the completion of the annual maintenance.

b) All work will be completed in accordance with industry standards.