Attachment_1_through_5.pdf

ATTACHMENT 1

Jefferson Laboratories On-Site Laboratory Equipment Maintenance, Repair, and Fabrication Services

Performance Work Statement (PWS)

1. BACKGROUND. The National Center for Toxicological Research (NCTR) and the Arkansas Regional Laboratory of the Office of Regulatory Affairs (ARL/ORA) are located at the Jefferson Laboratories of the U.S. Food and Drug Administration (FDA) in Jefferson, Arkansas, approximately 35 miles south of Little Rock and 28 miles north of Pine Bluff.

NCTR is an internationally recognized FDA research center that conducts toxicological research studies and other research activities designed to support the FDA’s mission to protect the public’s health. NCTR investigators partner with researchers elsewhere in the FDA as well as other government agencies, industry, and academia. NCTR is comprised of six research divisions and has facilities including: 132 general or special purpose research laboratories; animal facilities, including rodent facilities accommodating conventional housing, a specific pathogen free rodent production colony, isolators for germ-free rodents, and quarantine; a non-human primate research center; a zebrafish production facility; a phototoxicology research center; an imaging center including microPET, MRI, and CT scanner; a nanotechnology core facility; and an inhalation toxicology facility. ARL is an ORA field laboratory with Food Chemistry, Pesticide, and Microbiology laboratories tasked with analyzing a wide variety of samples from foods and cosmetics. Although much of the scientific equipment at the Jefferson Laboratories complex is covered under manufacturer’s service agreements, many critical items are not. These items must be maintained in working order. In addition, some research projects require specialized items that must be designed and fabricated to order. This on-site service contract is required to provide maintenance, repair, and fabrication of scientific equipment that must remain in operating condition for continuous use in research and testing facilities. On-site laboratory equipment maintenance, repair, and fabrication services for NCTR have been obtained through contracts since 1977.

2. DEFINITIONS. As used throughout this PWS, the following terms shall have the meaning set forth below and specified as applicable to this project.

2.1. Contracting Officer (CO). A Government employee with the authority to enter into and administer contracts and make determinations and findings with respect thereto, or with part of such authority.

2.2. Contracting Officer’s Representative (COR). A Government employee who provides technical clarification and guidance with respect to the PWS and serves as the technical liaison between the Contractor and the CO.

2.3. Contractor. Refers to both the Prime Contractor and all Subcontractors. The Prime Contractor shall be responsible for ensuring that its Subcontractors comply with the requirements of this

PWS.

2.4. Contractor Performance Assessment Reporting System (CPARS). The Government’s automated system for reporting Contractor performance in at least the following areas: Quality of Product or Service; Scheduling; Cost Control; Business Relations; Management of Key Personnel; and Utilization of Small Business (subcontracting). (CPARS training:

https://www.cpars.csd.disa.mil/allapps/cpartrng/webtrain/webtrain_all.htm)

2.5. Good Laboratory Practice (GLP). A set of regulations that applies to animal and non-animal research and safety studies funded or reviewed by the FDA. The regulations are a quality system of management controls for research laboratories and organizations to try to ensure the uniformity, consistency, reliability, reproducibility, quality, and integrity of non-clinical safety tests. (21CFR, Part 58;

http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?CFRPart=58 &showFR=1).

2.6. Government Furnished Property (GFP). All Government facilities, property, and supplies provided to the Contractor to be used by the Contractor in carrying out responsibilities set forth in this PWS. Ownership of GFP remains that of the Government at all times (unless and until consumed or expended in the normal course of business) and all GFP shall be returned or accounted for upon completion of the contract.

2.7. Instrument Support Services Work Order Request (ISSWOR). A computer based (PC compatible) maintenance management program capable of incorporating and reporting maintenance history of the laboratory equipment as well as the standard work order information.

2.8. Master Approved Technologies List (MAT List). The MAT list contains FDA-approved electronic devices and software. All electronic devices and software used with FDA computers and systems must be on the MAT list prior to purchase or use.

2.9. Multispecies Behavioral Systems (MBS). MBS units are fabricated by the Contractor for behavioral studies involving rodents, non-human primates, humans, or other species.

The units generally provide rewards for pressing levers in response to stimuli.

2.10. Past Performance Information Retrieval System (PPIRS). A web-enabled, government-wide application that provides timely and pertinent contractor past performance information to the Federal acquisition community for use in making source selection decisions. Reports from CPARS are transmitted to PPIRS.

Government access to PPIRS is restricted to those who are working on source selections and Contractor access is restricted to viewing only data regarding their contract. PPIRS registration:

http://www.federalcontractorregistry.com/?gclid=COuDgOyOpLwCFcdQOgodPHMA qA.

2.11. Prototype Instrumentation. A new item built/fabricated for a user, inclusive of integrating parts from item(s) to make up the new item.

2.12. Quality Assurance Unit (QAU). The NCTR QAU in the Regulatory Compliance and Risk Management office conducts audits, inspections, and reviews to assess compliance with approved study protocols, established Standard Operating Procedures (SOPs), and the FDA’s GLP for Nonclinical Laboratory Studies (21 CFR Part 58).

QAU observations are reported to the responsible laboratory personnel, study director, investigators, and management.

2.13. Quality Control Plan (QCP). A document that includes all measures to be taken by the Contractor to ensure that the quality of an end item service meets the contract requirements regarding timeliness, accuracy, appearance, completeness, consistency, and conformity to appropriate standards and/or specifications. It includes, but is not limited to, a written set of self-inspection checklists developed by the Contractor that comprehensively detect variations from the contract requirements; recording of work data; trend analysis; feedback and control systems for correcting deficiencies; and the necessary documentation to record findings.

2.14. Regulatory Compliance and Risk Management (RCRM). RCRM is the office responsible for NCTR’s Safety, Security, Archives, and QAU. Federal employees in this office conduct safety training and inspections, as well as QA inspections.

2.15. Restricted Areas. Special clearance procedures are required for access to the Non- Human Primate (NHP) facility. Access to the NHP facility may be obtained when the following criteria are met: 1) legitimate need to enter the facility; 2) completion of NCTR NHP safety training; 3) negative tuberculosis test, positive measles titer, and respirator fit test; 4) NHP Facility Supervisor briefing; and 5) approval from the Director of Veterinary Services. In addition, access to the rodent breeding colony (a Specified Pathogen Free [SPF] area) is restricted so that no one may enter after previously having been in a conventional rodent facility on the same day. While in these areas, Contractor personnel are subject to applicable Jefferson Laboratories SOPs, which will be made available to those who are permitted access.

2.16. Standard Operating Procedures (SOPs). A formally documented specific set of procedures to be followed in carrying out a given operation or in a given situation.

3. LIST OF APPENDICES.

Appendix 1: Current Jefferson Laboratories Equipment to be Maintained Appendix 2: Historical and Estimated Workload Data Appendix 3: Screen Shot from ISSWOR System Appendix 4: List of Current SOPs Appendix 5: List of Equipment Types and Maintenance Types Appendix 6: Preventative Maintenance Equipment List Appendix 7: Design and Fabrication Requests (2009 – 2013) Appendix 8: Floor Plan for Building 17 Appendix 9: Government Furnished Property (GFP)

4. SCOPE OF WORK.

4.1. General Information. The Contractor shall conduct the laboratory equipment maintenance, repair, and fabrication services following all rules, policies, regulations and guidelines set-forth herein. The Contractor shall be knowledgeable and trained on the standards of maintenance, repair, and fabrication of scientific equipment.

A current list of the equipment to be repaired and maintained is in Appendix 1. The Government routinely acquires new equipment to replace aging equipment, to furnish new laboratory space, or to expand laboratory capabilities as new technology becomes available. The Contractor shall provide the services described herein for any instruments or equipment acquired by the Jefferson Laboratories during the course of the contract.

The Contractor shall provide all labor, to include but not be limited to supervision, administrative, and technical support, to plan, schedule, coordinate, and assure effective completion of all services described herein. The required services are described below.

See Appendix 2, Historical and Estimated Workload Data for additional information on past, on-going, and anticipated workload.

4.2. Administrative Services and Management. The Contractor shall provide complete on-site supervision to carry out all of the terms and conditions of this PWS.

4.2.1. Environment, Health, and Safety. The Contractor shall be responsible and qualified to handle all health and safety requirements with a point of contact to be provided to the COR upon appointment. The appointed, qualified point of contact for the Contractor shall serve as the liaison to the Jefferson Laboratories Environment, Safety, and Health Committee.

4.2.2. Standard Operating Procedures (SOPs). SOPs for areas, operations, and procedures directly within the Contractor's responsibility shall be written and maintained by the Contractor to reflect the current procedures used by their firm.

The Contractor shall enforce SOPs to ensure that procedures are conducted as specified. The Contractor shall be responsible for developing its own SOPs without direction from the Government. All SOPs shall be delivered to the COR and NCTR’s QAU for review.

Review of SOPs by the COR or NCTR’s QAU is not intended as, and shall not be construed as, approval or any assumption of responsibility or liability by the Government.

During periods of Contractor transition, the new Contractor shall perform services under guidelines of SOPs in place at the time duties are assumed and until such time that the SOPs are revised, if necessary.

4.2.3. Tracking Tasks/Work Orders. The Contractor shall use an automated maintenance program to initiate and track work orders and to indicate maintenance history. Work requests may come via telephone, email, fax, or in person and must be entered into the system within 1 hour of receipt.

The Government shall furnish a maintenance program, ISSWOR, for the Contractor’s use (see Appendix 3 for a screen shot of this program). The Government shall have access to all data about work performed under this contract indefinitely, independent of the Contractor that provides the services.

The Contractor shall provide to the COR or CO the logs/records upon request. The automated work order system’s logs/records shall contain at a minimum:

4.2.3.1. Date and type of service performed (i.e. preventative maintenance, repair, fabrication, modification, alignment, testing, calibration, or standardization).

4.2.3.2. Type and location of equipment services, including manufacturer, model and serial number, and FDA decal identification number and/or bar code information.

4.2.3.4. Man-hours expended.

4.2.3.5. Name of user who reported the equipment malfunction.

4.2.3.6. Name of user who accepted the equipment after repairs.

4.2.3.7. Date and time work order was opened and closed.

4.2.4. Quality Control. The Contractor shall provide all quality control for services performed under this contract. The Quality Control program shall be designed to ensure that the Contractor is providing laboratory equipment maintenance, repair, and fabrication services in compliance with established SOPs and GLP requirements. The Contractor shall write, implement, and enforce a Quality Control Plan (QCP).

The QCP shall be designed to monitor all functions in laboratory equipment maintenance, repair, and fabrication services to confirm that activities are complete, accurate, and in compliance with established SOPs and GLP requirements.

4.3. Repair and Maintenance Services. The Contractor shall perform repairs and maintain the various types of laboratory instruments and equipment at Jefferson Laboratories in accordance with the manufacturer’s maintenance/repair procedures, SOPs (see Appendix 4 for a list of current SOPs), and GLP requirements. These services shall include but may not be limited to troubleshooting; testing components and systems; maintenance and repair of equipment and instruments and any associated computers and printers;

maintenance and repair of the computer network hardware; coordinating with various manufacturers’ personnel to service items such as pagers and two-way radios, and to relocate or install laboratory equipment; and obtaining manufacturers’ manuals. A list of the types of equipment and the types of maintenance to be provided is in Appendix 5.

As a part of the repair and maintenance of laboratory equipment, the Contractor shall maintain software components on instrument computers that are (1) running any Windows operating system previous to Windows 7 and (2) not on the FDA network.

These activities include, but are not limited to:

4.3.1. Troubleshooting operating system problems

4.3.2. Troubleshooting software

4.3.3. Backing up data to approved devices (see Section 2.9 MAT list)

4.3.4. Installing new software

4.3.5. Keeping virus protection up-to-date (when available)

4.3.6. Escorting vendor support personnel – the Contractor shall ensure that vendor service technicians have necessary access to laboratory equipment computers without breaching FDA security

4.3.7. Maintaining local accounts on non-networked computers

Any software or electronic devices, including data storage devices (e.g. external hard drives, USB flash drives, etc.), must be on the MAT list prior to use with FDA computers.

All software components on all Windows 7 computers and all computers on the FDA network are managed by FDA personnel. A list of computers to be maintained by the Contractor shall be provided when FDA personnel have completed a review of all computers on the Complex.

Any time that the contractor maintains or repairs equipment used in the generation, measurement, or assessment of data (and, where applicable, equipment used for facilities’ environmental controls) in support of or in safety testing for nonclinical laboratory studies designated for GLP compliance, such actions/operations shall conform to the requirements of FDA GLP regulations 21CFR, Part 58, including but not limited to Sections 58.61, 58.63, 58.81, and 58.195(f).

The Contractor shall continue to provide repair and maintenance services in the event that the Government makes alterations, installs attachments, or makes substitutions or additions to equipment, or in the event that equipment is moved to another location within the Complex.

The Contractor shall coordinate with Jefferson Laboratories staff or other Contractors to facilitate equipment installation (e.g., any cables or pipes that will penetrate walls, ceilings, or any structure shall be installed by the Jefferson Laboratories Complex Staff or the on-site Contractor for Operation and Maintenance of Facilities).

The Contractor shall coordinate with manufacturer’s personnel (e.g., those who perform warranty-covered repairs on equipment) as an intermediary between the manufacturer and the equipment users to provide services including, but not limited to, notifying the service contractor of the needed repairs, escorting the contractor to the equipment, assisting with relocation and installation, and ensuring that proper documentation (i.e., repair ticket, invoice, etc.), is forwarded to the Government office responsible for the equipment. This work is included in the man-hours and work orders in the workload history in Appendix 2.

The Contractor shall provide the information for all required parts to the Division or Office to which the equipment is assigned. The Division or Office shall determine whether to repair or replace equipment and shall make the purchase of parts or equipment.

Work shall be performed on a first-come, first-served basis, unless the COR authorizes a higher priority for a particular work order. Routine maintenance shall commence within four (4) working hours after a complete work order that properly identifies the equipment and its malfunction has been initiated. Maintenance and repairs shall be completed within three (3) working days, unless waiting on parts.

4.4. Preventative Maintenance Program. The Contractor shall follow and maintain a Jefferson Laboratories’ Preventative Maintenance schedule, which shall include equipment used in GLP studies and other equipment designated by users. Equipment on the current Preventative Maintenance schedule is listed in Appendix 6. The Contractor shall schedule and perform preventative maintenance as recommended by manufacturers. The Government may request deviations from the scheduled times to avoid interruption of ongoing work. Should this occur, the Contractor shall coordinate with the equipment user(s) to reschedule the preventative maintenance.

4.5. Design and Fabrication of Prototypes. The Contractor shall provide design and fabrication of prototype instrumentation or equipment as approved by the COR. The Contractor shall analyze the proposed project with the research personnel making the request and provide to the COR a recommended approach to accomplish the project.

Each project shall be performed under an approved work order and shall be entered into the automated maintenance program.

For each prototype that is developed, the Contractor shall produce, maintain, and provide to the COR documentation to include at a minimum: a description of the hardware that has been fabricated, including instructions for use; a description of any software required to operate the instrument, including instructions for use; and a recommendation for maintenance support that the instrument may require, including a maintenance schedule.

A list of fabrications performed from 2009 to 2013 is in Appendix 7.

4.6. Off-site Instrument Maintenance and Repair. A few of NCTR’s instruments are located with collaborators at other institutions. The instruments are MBS units fabricated by the current Contractor. Currently, two MBS units are located at the Arkansas Children’s Hospital in Little Rock; one MBS unit is at the Mayo Clinic in Rochester, Minnesota; and one MBS unit is at the University of Iowa in Iowa City, Iowa. Two additional units were under development in early-to-mid 2014 for placement in Mexico City, Mexico and at Mt. Sinai in New York City, New York; and two more units were being planned for additional sites that have not been identified at this time.

Each year, the Contractor shall set up one MBS unit for humans at the Museum of Discovery in Little Rock for a one-day demonstration.

The Contractor shall provide maintenance and repair services for these off-site instruments, primarily through technical assistance over the phone to users at the off-site locations. If maintenance or repair services require a contract employee to travel, prior approval from the CO shall be required.

4.7. Qualifications. The Contractor shall provide qualified technical personnel to fulfill complete laboratory equipment maintenance, repair, and fabrication services as outlined above. At least one on-site contract employee shall have a valid HVAC contractor’s license.

5. GOVERNMENT FURNISHED PROPERTY (GFP) AND SERVICES

5.1. Facilities. The Government will provide utilities (electricity, gas, water, telephone, and internet access for Government supplied computers only). The Government will provide the following support services on-site: library services, personal computer training, bulk document reproduction, mail services (delivery of incoming mail and pick-up of outgoing mail), shipping (UPS or FedEx) and receiving, and recycling receptacles and pick-up. The majority of equipment repair and maintenance services will be performed at Jefferson Laboratories, 3900 NCTR Road, Jefferson, Arkansas 72079 (see Section 4.6 for an explanation of off-site instruments).

On-site facilities are located in building 17 and include approximately 3,220 square feet of office, workshop, and storage space. Floor plans for the space are in Appendix 8.

The space is roughly distributed as follows:

5.1.1. Offices and storage: seven (7) rooms with a total of approximately 805 square feet of space.

5.1.2. Workshop: approximately 2414 square feet of space.

Most maintenance and repair work will be performed wherever the equipment is located on the Complex. The Contractor shall be responsible for the logistics involved in moving tools, parts, etc. to various areas on the Jefferson Laboratories Complex using the transportation provided (i.e., golf carts). Some equipment is located in restricted areas (see Section 2.15).

5.2. Equipment and Supplies.

5.2.1. The Government will provide all office equipment (e.g. desks, chairs, filing cabinets, phones, etc.) and office supplies (e.g. pens, paper, toner, etc.) directly required to provide the equipment maintenance and repair services described herein. The Contractor shall recycle non-confidential documents whenever they are no longer needed.

5.2.2. The Government will provide laptop computers that may be used in the process of equipment maintenance and repair and laptop or desktop computers in the offices of Contractor employees. Only Government-supplied computers may be connected to the FDA network. All Contractors with access to FDA computers shall complete annual computer security training to maintain computer access. The Government will provide all IT software support for Government furnished computers. The

Contractor shall turn off all computers that are not attached to equipment, or otherwise required to continue running, at the end of each week to conserve power.

5.2.3. Pursuant to the “Government Property” clause in Section III.1.1, the equipment to be provided for use/operation by the Contractor is listed in Appendix 9.

5.2.4. The Contractor shall be fully responsible for loss, destruction, or damage resulting from willful negligence or lack of good faith of any of the Contractor’s personnel to maintain and administer the program for maintenance, repair, protection, and preservation of the property in accordance with the clause in Section III.1.1, entitled “Government Property”.

5.2.5. In addition to the applicable “Government Property” clause in Section III.1.1, the Contractor shall comply with the provisions of DHHS publication “HHS Contracting Guide for Contract of Government Property”, which is hereby incorporated by reference (http://ncioa.cancer.gov/oa-internet/reference/Appendix_Q_HHS_Contracting_Guide-508.pdf ).

Exceptions to information in the Guide:

5.2.5.1. The Sensitive Item List referred to in the Guide is replaced by the following list:

a. Central Processing Unit (CPU) Assemblies

b. Weapons (including tranquilizer guns)

c. Voice Recorder/Transcriber

d. Pagers

e. Facsimile Machines

f. Freezers

g. Gamma Counters

h. Geiger Counters

i. Incubators

j. Laser Disc Players

k. DVD Players

l. Laboratory Balances

m. Liquid Scintillation Counters

n. Microwave Ovens

o. Photographic Cameras and Lenses

p. Portable Gas Generators

q. Refrigerators

r. Scanners

s. Spectrophotometers

t. Televisions

u. Video Recorders

v. VCRs

w. Power Tools >$100

x. Microscopes

y. 2-Way Radios

z. Monitors

aa. Printers

bb. Copiers

cc. Weapons (including tranquilizer guns)

5.3. The Government will provide all consumable materials and supplies required to directly perform the equipment maintenance and repair services. The Contractor is responsible for maintaining, through purchase requests to the COR, a level of inventory of commonly used supplies (e.g. nuts, bolts, solder, valves, etc.) to meet workload demands.

6. GENERAL WORK REQUIREMENTS.

6.1. Normal Working Hours. The Government’s primary operations at NCTR are conducted during the day from 8:00 am to 4:30 pm, Monday through Friday, except Federal holidays. The ten Federal holidays include New Year’s Day, Martin Luther King Day, Presidents’ Day, Memorial Day, Independence Day, Labor Day, Columbus Day, Veterans Day, Thanksgiving Day, and Christmas Day.

Contractor employees performing duties for the FDA are not automatically relieved from duty by virtue of the fact that the Government employees are dismissed or given the day off.

6.2. Physical Examinations. The Government requires all personnel working in laboratories on this contract to submit to the medical examinations or procedures listed below annually as a condition of employment. Possible adverse health outcomes as a result of exposures in the laboratory environment are monitored to ensure that contract employees may safely continue to work in the laboratory. All of these medical procedures will be provided by the NCTR, or a third party designated by NCTR at no cost to the Contractor or employee on an annual basis as long as the employee continues to work in laboratory areas. Medical examinations or procedures other than those approved by the NCTR or an NCTR-designated third party will be at no cost to the Government.

6.2.1. Periodic blood and urine samples as dictated by the safety and occupational health program.

6.2.2. Periodic examination for the presence of potentially pathogenic bacteria and viruses.

6.2.3. Follow-up examinations as determined necessary.

6.3. Conduct of Contractor Employees. The Contractor’s employees shall adhere to standards of competency, conduct, appearance, and integrity that reflect credit to the employee, the Contractor, and the Government. The Contractor shall be responsible for such disciplinary action with respect to their employees as may be necessary.

The Contractor shall immediately report to the CO and COR in writing any planned termination of contract personnel and the cause of such termination. The Contractor shall not terminate any employee without prior notification to NCTR RCRM and shall take no action toward employee termination until NCTR RCRM and Security staff are present. NCTR RCRM and Security staff shall escort terminated contract employees at all times while on FDA property.

Contractor personnel shall comply with the NCTR’s traffic and safety rules and other regulations and instructions pertaining to conduct of persons on Government facilities.

Contractor personnel shall, in no event, enter any area to which access is restricted, unless such an area has been specifically identified as an area in which services are to be rendered. The Contractor shall place their employees on notice that infraction of any of the above rules, regulations, or prohibitions may be grounds for removal from Government property.

Note: Tables are presented for Accountable (pages 1- 6) and Non-Accountable (pages 7-13) property to be maintained for Jefferson Laboratories.

Appendix 1: Current Equipment (Accountable Property)

TIME IN-SERVICE DESCRIPTION NUMBER

N/A 5th Wheel Hauler 4 >5 years Air Compressor, Hydrovane 1 >5 years Amplifier 1 >5 years Anaerobic Chambers (Gloveless) 6 >5 years Analog Input Channel/Pressure 1 >5 years Analyzers (including acid, blood gas, chemistry, clinical, cytometry, DNA, free radical, hematology, isocratic , and liquid scintillation)

5 years Analyzers (including hematology and genetic) 2 >5 years Array Systems (Binary and Diode) 2 5 years Array Systems 1 >5 years Autoclave 1 >5 years Automicrobic System 1 >5 years Autosamplers 37 5 years Autosamplers 1 >5 years Auto Sputter Coater 1 6 years Balances, Analytical 3 >5 years Behavioral Equipment Startle System 1 >5 years Bioanalyzers 7 5 years Bioanalyzers 1 >5 years Bioreactor 1 >5 years Biorobot System 1 >5 years Cabinet, Biosafety 2 5 years Calorimeter 1 >5 years Cameras/systems 17 >5 years Centrifuges 66 5 years Centrifuges 18 >5 years Centrifuges Microcentrifuges 4 >5 years Centrifuges, Ultra 4 >5 years Chemostat, Culture 1 >5 years Chemstation 1 >5 years Computer Servers 56 5 years Computer Servers 1 >5 years Computers, Desktop 485 5 years Computers, Desktop 132 >5 years Computers, Laptop 356 5 years Computers, Laptop 427 >5 years Concentrators 3 >5 years Console In/Out 1 >5 years Containment System, Animal 1 5 years Control Unit 1 >5 years Controllers 5 5 years Coulometer 1 >5 years Counters 11 5 years Counters 3 >5 years Crosslinker, Ultraviolet 1

TIME IN-SERVICE DESCRIPTION NUMBER

>5 years Cryostat 3 >5 years CT Scanner 1 >5 years Cytometers (Flow and Cell Sorters) 14 5 years Cytometers (Flow and Cell Sorters) 2 >5 years Data Acquisition System 1 >5 years Delivery System, Solvent 8 5 years Densitometer 1 N/A Desorber, Solid Sorbent Tube 1 >5 years Detectors (including absorbance, electrochemical, fluorescence, HPLC, light scattering, radiation, refractive index, and wavelength)

5 years Detectors (including absorbance, electrochemical, fluorescence, HPLC, light scattering, radiation, refractive index, and wavelength)

>5 years Detectors Chromatographs 4 >5 years Detectors Liquid Chromatographs 15 5 years Detectors Liquid Chromatographs 2 >5 years Digitizer, Graphics 1 >5 years Dispenser, Reagent 1 >5 years DNA Sequencer 11 >5 years DNA Typing Base System 1 >5 years Electrocardiogram 1 >5 years Electrometer 1 >5 years Electrophoresis Systems 14 >5 years Embedding Centers 3 >5 years Euthanizer 1 5 years Euthanizer 2 5 years Evaporator Centrifugal Vacuum Concentrator 1 >5 years Evaporator Centrifugal Vacuum Concentrator 1 >5 years Evaporator Speedvac Systems 11 5 years Evaporator Speedvac Systems 1 5 years Evaporator, Vacuum 1 >5 years Exercixe Equipment Gravitron Upper Body System 1 >5 years Extension Arm 1 >5 years Extractor 1 >5 years Fraction Collector 2 >5 years Filter System, Automatic 2 >5 years Filter Unit 2 N/A Flame Ionization Detector Gas Station 1 N/A Flash E Nose 1 >5 years Fluorometer 1 5 years Fluorometer 2 >5 years Fraction Collector 1 >5 years Fractionator 1 5 years Fractionator 2 >5 years Fraction Gradient System 2

TIME IN-SERVICE DESCRIPTION NUMBER

>5 years Freeze Dryer 1 >5 years Freezer 4 5 years Freezer 1 >5 years Gas Chromatographs 18 >5 years Gaussmeter w/Three Axis Probes 1 >5 years Generators 2 >5 years Generator, Radiographic 1 >5 years Grinders 2 >5 years Histostainer 1 >5 years Homogenizers 4 >5 years HPLC (integrated and solvent delivery systems) 14 5 years HPLC (integrated and solvent delivery systems) 3 N/A HPLC Monitor & Recorder System 1 5 years Hybridization System 1 >5 years Identification System 4 >5 years Imaging Systems 15 5 years Imaging Systems, including digital 2 >5 years Imaging Systems Gel Documentation Systems 5 >5 years Incubators (including CO2 and shaking) 52 5 years Incubators (including CO2 and shaking) 10 >5 years Instrument ECT 2 5 years Instrument Stereotaxic 1 >5 years Ion Trap System 1 >5 years Isolation Transformer 1 >5 years Isolator 1 >5 years Laser 2 5 years Laser Capture Microdissection 1 >5 years Laser Modulator 1 >5 years Laser Source Fiber Optics 1 >5 years Light System 1 >5 years Light Cycler 1 >5 years Lyophilizer 1 5 years Machine Lathe 1 5 years Machine Milling 1 >5 years Measuring System, Energy Power 1 >5 years Measuring System, Nitric Oxide 1 >5 years Metal Detector 1 >5 years Microarray Scanner 1 >5 years Microforge 1 5 years Microplate Readers 7 >5 years Microplate Readers (including with imagers) 26 >5 years Microplate Storage System 1 >5 years Microscopes (including light, field emission electron, digital, inverted, probe scanning, 5 years Microscopes (including light, field emission electron, digital, inverted, probe scanning, TIME IN-SERVICE DESCRIPTION NUMBER

>5 years Microscopes Stereomicroscope 1 >5 years Microstation 1 >5 years Microtomes 30 >5 years Microwave Digestion System 1 5 years Microwave Digestion System 2 5 years Microwave Synthesis System 1 >5 years Microwriter Carousel Cassette 1 >5 years Mixer, Audio 1 >5 years Molecular Weight Analyzer 3 5 years Monitor, Brain Activity 1 >5 years Nebulizer, Ultrasonic 1 >5 years NIR Analyzer 1 >5 years Nitrogen Determination 1 5 years Nitrogen Generators 2 >5 years Nitrogen or Hydrogen Generators 12 >5 years Optical Head w/Integrating SPH 1 >5 years Oscilloscope, Electronic 2 5 years Oscilloscope, Electronic 1 >5 years Oven, Vacuum 1 >5 years Oximeter System (including Pulse Oximeter) 2 >5 years PCR Mate EP Synthesizer 1 >5 years Photocopier 2 >5 years Photomicrographic System 1 >5 years Pipette, Automatic 1 >5 years Pipette Calibration System 2 >5 years Pipetting System 1 5 years Pipetting System 1 >5 years Polarimeter 1 >5 years Polygraph 1 >5 years Power Supply 3 >5 years Printers 5 5 years Printers 5 >5 years Probe (including Multinuclear) 2 >5 years Processor Cell, High Voltage 1 >5 years Processor, Magnetic Particle 1 >5 years Processor, Sample 1 >5 years Projector 3 >5 years Protein Digestion Station 1 5 years Pump, Binary 1 >5 years Pumps (including capillary, HPLC, and quarternary) 13 >5 years Purification System 2 5 years Purification System 1 N/A R.A.P.I.D. System 1 >5 years Reaction System 1 >5 years Reader, Microplate 2 >5 years Recorder (Film and Video Cassette) 2

TIME IN-SERVICE DESCRIPTION NUMBER

>5 years Recycling System, Solvent 5 >5 years Reverse Osomosis System 1 >5 years Robotics System 2

N/A RV 2

>5 years Sample Analyzer System 1 >5 years Sample Oxidizer System 1 >5 years Sample Preparation System 5 5 years Sample Preparation System 1 >5 years Sampler, Microdialysis 2 >5 years Scanner, Array 2 >5 years Scanner, Digital Slides 1 >5 years Scanner, Document 11 >5 years ScanScope 1 >5 years Scintillation Counter System 1 >5 years Scrubber 2 >5 years Separation System 1 >5 years Shuttle Avoidance System 1 >5 years Signal Conditioner 2 >5 years Slicer, Tissue 1 >5 years Solvent Module 7 >5 years Spectrofluorometer 1 >5 years Spectrograph 3 5 years Spectrometers 1 >5 years Spectrometers (including particle counter) 21 >5 years Spectrometers Mass Spectrometers 13 5 years Spectrometers Mass Spectrometers 2 >5 years Spectrophotometers 45 5 years Spectrophotometers 2 >5 years Spectroradiometer 1 >5 years Spectroscopy System 1 >5 years Stainer Gram Slide Aerospray 2 >5 years Stereotaxic Animal 1 >5 years Sterilizer, Table Top 1 5 years Syringe Pump 1 >5 years System Cancelling 1 5 years System Cancelling 1 >5 years System Tester Radiofrequency Electromagnetic Field Exposure 1

>5 years Tape Library AIT 1 >5 years Telemetry System 1 >5 years Test System 1 >5 years Thermal Cycler (including real time PCR systems) 72 5 years Thermal Cycler (including real time PCR systems) 3 >5 years Tissuelyser 3 >5 years Tissue Processors 10 >5 years Tracer 1

TIME IN-SERVICE DESCRIPTION NUMBER

>5 years Vaporizer, Isoflurane 1 >5 years Ventilator 1 5 years Vessel Cleaning System 2 >5 years Water Activity System 1 5 years Water Purification System 1 >5 years Workstation (including analytical, evaporation, HPLC, Imaging, NT, star, and video)

5 years Workstation (including evaporation and pipetting) 2 >5 years X ray Field Source 1 >5 years X ray Unit 3

(Non Accountable Property)

DESCRIPTION NUMBER

Air Filter 1 Air Compressor 1 Amplifier Clamp 1 Angle Grinder 1 Arbor Press 1 Asperator 2 Attenuator 2 Autoclaves (benchtop) 7 Automatic Liquid Sampler, Thermal 2 Auto Samplers 3 Bag Sealer Impulse Sealer 2 Balances 315 Band Saw 2 Behavioral Equipment Animal Warning System 3 Behavioral Equipment Avoidance Monitor 4 Behavioral Equipment Barnes Maze (mouse and rat) 3 Behavioral Equipment Elevated Plus Maze 4 Behavioral Equipment Elevated Tee Maze 2 Behavioral Equipment Escape Box 2 Behavioral Equipment Multi Behavioral System Primate Chambers 12 Behavioral Equipment Multi Behavioral System Primate Chambers Oil Blowers 1 Behavioral Equipment Open Field 2 Behavioral Equipment Startle Response System 8 Behavioral Equipment Zero Maze 2 Belt Sander 2 Bench Grinder 1 Blender 2 Breakout Box 1 Cabinet Saw 1 Calculator 1 Caliper, Dial 2 Camera 39 Capping Station 2 Cell Counter 7 Cell Disrupter 1 Cell Meter 2 Centrifuges 152 Centrifuges Microcentrifuge 2 Centrifuges Mini Centrifuge 19 Chlorine Flush Station 1 Chromato Vue 1 Circuit Tester/Designer 1 Circular Saw 1 Circulators 20 Clippers 1 Cold Stage Controller 1

DESCRIPTION NUMBER

Controller 5 Counter Timer 1 Cryo Evaporator 1 Cryo Monitor 1 Cryoplunge 1 Cutoff Saw 1 Dad 1 Degasser 4 Desicator 1 Detector 1 Dial Depth Guage 1 Diamond Band Saw 1 Digital Flow Meter 1 Digital Readout 1 Dispenser 208 Display Scope 1 Doc Sealer 1 Document Communication System 1 Drill 4 Drill Press 3 Droplet Generator 1 Droplet Reader 1 Dry Bath 2 Dual Bath 3

DVR 4

EIA Tester 1 Electrometer 1 Electrophoresis Gel Cell 30 Electrophotometer 1 Epithelial Voltohmmeter 1 Evaporator Speed vacs 28 Exercise Equipment Ab Bench 1 Exercise Equipment Drive Exerciser 1 Exercise Equipment Elliptical 3 Exercise Equipment Elliptical Bike 1 Exercise Equipment Lat Pulldown 1 Exercise Equipment Leg Extension 1 Exercise Equipment Pec Exercise 1 Exercise Equipment Recumbent Bike 1 Exercise Equipment Stair Master 1 Exercise Equipment Stationary Bike 1 Exercise Equipment Treadmill 4 Exposure Chamber 1 Fax Machines 19 Fiber Illuminator 1 Fiber Optic Kit 1

DESCRIPTION NUMBER

Flex Shaft Tool 1 Fluorometer 1 Force Meter 1 Fraction Collector 1 Frequency Counter 1 Function Generator 3 Fyrite 2 Gas Purifier 2 Gauss Meter 1 Germinator 2 Hand Vac 4 Handheld Transceivers 6 Hearing Tester 1 Heat Bath 1 Heat Controller 1 Heat Exchanger 1 Heat Gun 1 Heat Therapy Pump 1 Heated Bead Bath 2 Heating Block 2 Heating Equipment Hot Plates (including with stirrers) 17 Heating Equipment Sample Heater 3 High Voltage Probe 1 Hole Punch/Stapler 3 Home Cage 3 Homeothermic Monitor 1 Homogenizer 5 Hood 1

HPLC 3

HPLC Pump 2 Humidity/Temperature Logger 1 HV Power Supply 3 HV Probe 3 Hydrolic Lift Cart 1 Impulse Soundmeter 1 Incubator (including micromixer) 11 Incubators, CO2 (including water jacketed) 62 Incubator, Dry 1 Intergrator 1 Isolation Table 1 Label Maker/Printer 6 Lamp Controller 2 Lamp, Ultraviolet 9 Lamp Ultraviolet Lamp Exposure System 2 Laser Power Meter 2 Leak Detector 1

DESCRIPTION NUMBER

Leak Detector, Gas 1 Light View Box 1 Liquid Nitrogen Monitor 1 Logic Probe 1 Masticator 1 Metal Bender 1 Metal Knotcher 1 Metal Lathe 1 Metal Shear 1 Meter 1 Micro Autosampler 1 Micro Manipulator 1 Micrometer 1 Micromite 1 Microscope 12 Microscope Stand 1 Microslicer 2 Microwaves 47 Milling Machine 1 Mixers 50 Mixer Gyromixer 1 Mixer Micro Mixer 2 Mixer Vortex Mixers (including digital) 10 Monitor 2 Multi Press 1 Multi Stirrer 4 Nitrogen Generator 1 Oil Filter 2 Oscillator 1 Oscilliscope 4 Oven 7 Oven, Hybridization 3 Oven, Rotating 1 Pager 82 Pager Programmer 1 Paging Console 1 PC/PS Tester 1 pH Meters 14 Photo Stands 7 Pico Amp Source 1 Pico Amp Meter 1 Pipetters (including multichannel) 674 Pipetters, Auto 5 Pipette Aid 1 Pipette Dispenser 2 Pipette Helper 1

DESCRIPTION NUMBER

Plastic Bender 1 Plate Reader 1 Plate Scanner 1 Plate Sealer 1 Plate Shaker 1 Plate Spinner 1 Plate Stirrer 1 Platform Shaker/Rocker 8 Plotters 4 Portable Sanitizer 1 Positive Pressure Manifold 1 Power Supply 20 Press 1 Pressure Reducing Station 3 Printers (including with copier/scanner) 361 Printer, 3 D 1 Protein Detector 1

PS 4

PS Tester 1 Pulse Amp 1 Pump 6 Pump, Circulator 1 Pump Nano Pump 1 Pump, Parastoltic 1 Pump, Vacuum Pressure 1 Pump, Vacuum 43 Pump, Varistaltic 2 Pumping Station 1 Radio 2 Radio Programmer 1 Ref Trap 1 Relative Humidity Ind 2 Repeater 7 Rework Station 1 RF Wattmeter 1 Rotator 1 Roto Rod 1 Roto Vap 1 Roto Torque 1 Running Wheels 1 Sample Spinner 1 Scaler 1 Scanners 15 Scope Probe 1 Scintillation Counters, Liquid 4 Shakers 20

DESCRIPTION NUMBER

Shredders 26 Soldering Iron 1 Soldering Station 9 Solvent Switcher 1 Sonic Bath 3 Sonic Cleaner 4 Sonicator 6 Spectrometers ICP/MS 1 Spectrometer NMR 2 Spectrophotometers 10 Speed Control 1 Spi Nim Bin 1 Spinner 2 Spot Welder 2 Sterilizer 1 Sterilizer, Bead Bath 1 Sterilizer, Loop 1 Stirrers 36 Stroboscope 1 Survey Meter 3 Switch Valve 1 Syringe Pump Interface 40 Syringe Pumps 29 Tachometer 1 Tail Pulse Generator 1 Temperature Controller 1 Temperature Programmer 1 Temperature Recorder 1 Temperature Transmitter 1 Thermal Conditioner 1 Thermal Cyclers 5 Thermal Mixer 5 Thermal Pump 2 Thermal Shaker 1 Thermo Stat Plus 1 Thermometer (including digital, platinum, and IR) 5 Thermometer, Recording 1 Tig Welder 1 Tissue Chopper 1 Tissue Disruptor 1 Exercise Equipment Toe Raise 1 Torch Set 1 Transceiver 2 Transistor Analyzer 1 Transmitter 1 Exercise Equipment Triceps Pushdown 1

DESCRIPTION NUMBER

Tube Notcher 1 Tubing Bender 1 Typewriter 1 Ultrasonic Cleaner 1 Ultrasonic Processor 1 Ultrasonicator 1 Ultraviolet Mineral 1 Universal Counter 1 Uttranic Processor 1 Vac u safe 1 Vacuum Cleaner 3 Vacuum Controller 3 Vacuum Gage 7 Vacuum Trap 2 Vibratone 1 Vision Tester 1 Water Baths (including shaking) 19 Water Chiller and/or Circulator 9 Water Maze 1 Water Purifier 2 Welder Timer 1

Appendix 2: Historical and Estimated Workload

Historical and Estimated Workload

Studies at NCTR are funded by different sources and are designed for various purposes. For example, studies to be used as the basis for regulatory decisions by the FDA are required to be performed following GLP guidelines (21 CFR, Part 58;

http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfCFR/CFRSearch.cfm?CFRPart=58&showF R=1). These guidelines include information about how equipment used in the studies must be maintained.

The equipment maintenance schedule will likely remain at levels similar to those of the last five years. The equipment repair and fabrication workloads will be dependent upon need, but will likely remain at levels similar to those of the last five years. Historical workload information is provided in the graphs below.

Figure 1 shows the historical number of man-hours expended over the period 2009 – 2013 on equipment maintenance, repair, and fabrication at Jefferson Laboratories. These hours represent time spent directly working on equipment and do not include time spent on logistics.

Figure 2 shows the historical number of work orders and preventative maintenance tasks over the period 2009 – 2013 at Jefferson Laboratories. Note that work orders completed closely match work orders received. The work order turn-around time is an important element of this contract due to the requirement that the equipment remain in operating order for research and testing laboratories.

Figures 3 and 4 show the historical number of work orders at Jefferson Laboratories over the period 2009 – 2013 by equipment type. Figure 3 shows the most common work order types (>20 work orders per year), and Figure 4 shows all other work order types (< 20 work orders per year).

Figure 1. Historical man-hours spent directly on equipment maintenance, repair, and fabrication projects at Jefferson Laboratories.

Figure 2. Historical numbers of work orders and preventative maintenance tasks at Jefferson Laboratories.

Figure 3. Work orders by most common equipment type at Jefferson Laboratories. Behavioral equipment includes mazes for rodents and multi behavioral systems for primates, rodents, humans, and swine.

Figure 4. Less common work orders by type at Jefferson Laboratories. Evaporators include rotary, centrifugal, and concentrator types. Heating equipment includes mantles, blocks, guns, immersion, IR, lamps, and sealers. Lamps include visible, shortwave, long wave, UV, and IR types. Ovens include paraffin, ashing, drying, vacuum, and hybridization types. Pumps include air, water, solvent, and vacuum types. Spectrophotometers include IR, visible, UV, and radiation types. Water equipment includes baths, recirculators, chillers, purification systems, and distillation systems.

Appendix 3: Screen Shot from ISSWOR System

Note:

Names, telephone numbers, and login information have been redacted.

@FDA.GOV | Logout

C r e a t e N e w W o r k O r d e r E q u i p m e n t C a t e g o r y M a i n t e n a n c e T y p e M o n t h l y S t a t i s t i c a l R e p o r t O r g a n i z a t i o n a l W o r k l o a d R e p o r t

O u t s t a n d i n g W o r k O r d e r s

Go Rows 15 Actions Cancel Create Work Order

Work Order Work Performed WO Num Status Request Date Requester Phone Number Division FDA Number Equipment Description Equipment Category Maintenance Type

42742 Received by Lab Maint

12/18/2014 03:07:04pm

Priority One Animal Husband / Diet Prep MT3113 MBS-P Lab Equip REM

42741 Received by Lab Maint

12/18/2014 12:30:02pm Neurotoxicology NA MBS-P Lab Equip PM

42740 Received by Lab Maint

12/17/2014 02:26:47pm

Priority One Animal Husband / Diet Prep L024 Lever Lab Equip REM

42739 Work Completed by Lab Maint

12/17/2014 12:48:30pm ARL 5134441 turbo-vap Lab Equip REM

42738 Received by Lab Maint

12/17/2014 09:22:50am Neurotoxicology NA MBS-P Lab Equip REM

42737 Waiting on Parts

12/17/2014 09:11:40am Systems Biology mt7750 reverse osmosis water system Lab Equip REM

42736 Work Completed by Lab Maint

12/16/2014 02:45:42pm

Biochemical Toxicology 4005311 NMR Lab Equip REM

42735 Work Completed by Lab Maint

12/16/2014 02:58:08pm

Priority One Animal Husband / Diet Prep MT3101 mbsp #2 Lab Equip REM

42734 Received by Lab Maint

12/16/2014 02:12:34pm

Priority One Animal Husband / Diet Prep MT3255 mbsp #12 Lab Equip REM

42733 Waiting on Parts

12/16/2014 09:33:52am

Priority One Animal Husband / Diet Prep clean air system

42732 Work Completed by Lab Maint

12/16/2014 07:54:29am

Biochemical Toxicology 4005311 NMR Lab Equip REM

42731 Work Completed by Lab Maint

12/16/2014 07:52:44am Systems Biology 4000191 NMR Lab Equip REM

42730 Received by Lab Maint

12/15/2014 01:13:45pm

TPA Pathology Contract 4007988 MICROTOME Lab Equip REM

42729 Work Completed by Lab Maint

12/15/2014 07:57:49am

Biochemical Toxicology MT 8076 pipette Lab Equip REM

42728 Work Completed by Lab Maint

12/15/2014 07:55:11am

Biochemical Toxicology MT 8077 pipette Lab Equip REM

1 - 15

Page 1 of 1New Work Order Request

Screen Shot from ISSWOR System

Appendix 4: List of Current SOPs

List of Current SOPs

SOP

Number SOP Title Effective

Date Review

Date

PM

1.03 Maintenance of Nonhuman Primate Operant Behavioral

Equipment 1/Feb/10 Revised PM

2.02 Maintenance of Laboratory Balances 1/Feb/10 Revised PM

3.01 Non-Routine Maintenance of Gas Chromatography-Mass

Spectrometry Instrumentation 1/Feb/10 Revised

4.01 Non-Routine Maintenance of Gas Chromatography

Instrumentation 1/Feb/10 Revised

5.01 Non-Routine Maintenance of Non-Chromatographic -Mass

Spectrometric Instrumentation 1/Feb/10 Revised

6.01 Maintenance of Nuclear Magnetic Resonance Spectrometry

Instrumentation 1/Feb/10 Revised PM

7.01 Maintenance of Laboratory Check Weights 1/Feb/10 Revised PM

8.01 Non-Routine Maintenance of Liquid Chromatography -Mass

Spectrometry Instrumentation 1/Feb/10 Revised

9.01 Non-Routine Maintenance of Liquid Chromatography

Instrumentation 1/Feb/10 Revised

10.01 Maintenance of Centrifuges with Routine Maintenance 1/Feb/10 Revised PM

11.01 Non-Routine Maintenance of Elemental Analyzer

Instrumentation 1/Feb/10 Revised

12.01 Maintenance of Optical Spectrometer 8/Feb/10 Revised PM

13.01 Maintenance of Refrigerated Chillers 8/Feb/10 Revised PM

14.02 Maintenance of Incubators 1/Jul/10 Revised PM

15.02 Non-Routine Maintenance of Sample Handling Equipment

1/Jul/10 Revised

16.01 Non-Routine Maintenance of Digital Integrators 8/Feb/10 Revised

17.00 Maintenance of Ovens... RESCINDED 8/Feb/10 RESCINDED

18.01 Non-Routine Maintenance of Tissue Disrupters 8/Feb/10 Revised

19.01 Non-Routine Maintenance of HPLC Column Ovens 8/Feb/10 Revised

20.01 Non-Routine Maintenance pH meters 8/Feb/10 Revised

21.01 Maintenance of Autoclaves and Sterilizer 8/Feb/10 Revised PM

22.01 Non-Routine Maintenance of Tissue Preparation Equipment 8/Feb/10 Revised

23.01 Maintenance of Oil-sealed Mechanical Vacuum Pumps 8/Feb/10 Revised PM

24.01 Non-Routine Maintenance of Particle Counters and Cell

Counters 8/Feb/10 Revised

25.01 Non-Routine Maintenance of Particle Analyzers and Cell

Sorters 8/Feb/10 Revised

26.01 Maintenance of Scintillation and Gamma Counters 8/Feb/10 Revised PM

27.01 Non-Routine Maintenance of PCR Instrumentation 8/Feb/10 Revised

28.01 Non-Routine Maintenance of Nitrogen Generators 8/Feb/10 Revised

29.01 Non-Routine Maintenance of Water Baths 8/Feb/10 Revised

30.01 Non-Routine Maintenance of Rotary Evaporators 8/Feb/10 Revised

31.01 Non-Routine Maintenance of Ultrasonic Baths 8/Feb/10 Revised

32.01 Non-Routine Maintenance of Water Deionizers 8/Feb/10 Revised

33.01 Non-Routine Maintenance of Optical Microscopes 8/Feb/10 Revised

Number SOP Title Effective

Date Review

Date

PM

34.01 Non-Routine Maintenance of Syringe Drive Pumps &

Peristaltic Pumps 8/Feb/10 Revised

35.01 Non-Routine Maintenance of Microwave Ovens 8/Feb/10 Revised

36.01 Non-Routine Maintenance of Supercritical Fluid

Instrumentation 8/Feb/10 Revised

37.01 Non-Routine Maintenance of Lyophilizers 8/Feb/10 Revised

38.01 Non-Routine Maintenance of Electrical Power Conditioners and Uninterruptable Power Supplies 8/Feb/10 Revised

39.01 Non-Routine Maintenance of Water Distillation Systems 8/Feb/10 Revised

40.01 Non-Routine Maintenance of French Presses 8/Feb/10 Revised

41.01 Non-Routine Maintenance of Electrophoresis Instrumentation…