Notice_of_Intent_for_AB_Sciex_mass_spectrometer.doc

United States

Food Safety

Administrative

Department of and Inspection

Services

Agriculture

Service

Division

The following represents the Notice of Intent that will be posted on FedBizOpps.gov.

The United States Department of Agriculture (USDA), Food Safety Inspection Service (FSIS) intends to negotiate solely with AB SCIEX LLC, to obtain four (4) SCIEX QTRAP® 6500 Liquid Chromatography Mass Spectrometry (LC/MS/MS) System.

The equipment is sole proprietary to AB SCIEX LLC is the only known source which can provide the required supplies to the current requirements. This procurement will be conducted under the authority of FAR 6.302-1 – Only One Responsible Source and no Other Supplies or Services will Satisfy Agency Requirements Citation: 41 U.S.C. 253(c)(1). The period of performance will be for a 12-month base period plus 4 option years.

The contractor shall supply an LC/MS/MS meeting the following specifications:

Mass Spectrometer to include:

A.) IonDrive Turbo V Source

B.) TurbolonSpray Probe-Heated IonSpray for Turbo V Source. Flow rate 5 to 3000 ul /min

C.) Atmospheric Pressure Chemical Ionization (APCI) probe for Turbo V Source. Flow rate 200 to 3000 ul.min

D.) Polarity switching time of 5 msec in MRM and sMRM modes

E.) Triple quad scan speed of 12,000 Da/sec, mass range 5-2000

F.) Linear trap scan speed of 20,000 Da/sec, mass range 50-2000

G.) Triple quad mass stability of 0.1 Da over 24 hours

H.) Sensitivity of this system shall produce a signal to noise ratio for the transition of the 609 to 195 ion of > 510,000:1 with 1 pg of reserpine injected on column

I.) The mass spectrometer must be able to acquire data in the following modes:

1.) Full scan MS and selected ion for both Q1 and Q3

2.) Product ion scanning

3.) Precursor Ion Scan

4.) MS-MS neutral loss or gain scanning

5.) MS-MS multiple reaction monitoring (MRM)

6.) MS3 scanning

7.) MRM3 scanning

8.) TripleTrap scanning

Agilent 1290 (UHPLC) to include:

A.) Binary Pump, Agilent 1290 with seal wash option.

B.) Autosampler, Agilent 1290 with cooling

C.) Multi Column Thermostat Compartment, Agilent 1290

D.) Instant Pilot Agilent 1200 (local control module).

Computer system requirements shall be as follows:

A.) Analyst software for control, data acquisition, and data processing on SCIEX QqQ and QTRAP® mass spectrometers. DVD, documentation, one Processing Workstation License and one Acquisition Workstation License shall be included.

B.) MultiQuant V.3.0.2 with SMRM Software License for quantitation of small and large molecule compounds.

C.) The operating system shall be windows 7 or equivalent

D.) The system shall include a monitor.

E.) Cabling for interfacing with the mass spectrometer shall be provided

This is not a request for quotations or an announcement of a forthcoming solicitation. Request for copies of this solicitation will not be honored or acknowledged. The Government does not intend to pay for information received. All interested parties must respond within one (1) calendar day from the date of this notice. Written responses must provide clear and concise documentation indicating your firm’s capability to provide the proprietary services. Verbal responses are not acceptable and will not be considered. When responding to this announcement, respondents should refer to announcement #903274. If no viable responses have been received in response after Friday, September 27, 2019, 4:00 pm E.S.T to this announcement, USDA/FSIS shall negotiate solely with AB SCIEX LLC.

Food Safety Inspection Service

5601 Sunnyside Ave. Beltsville, MD 20705

An Equal Opportunity Provider and Employer