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Cryopreserved Human, Mouse, and Rat Hepatocytes
Solicitation number
75N95023Q00551
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This purchase description outlines the need for cryopreserved human, mouse, and rat hepatocytes for use in drug metabolism experiments related to a malaria project. Specifically, it requests 40 vials each of cryopreserved human hepatocytes from Sekisui Xenotech catalog number HPCH10, cryopreserved male mouse hepatocytes from catalog number MPCH1000, and cryopreserved rat hepatocytes from catalog number RPCH1000. Also required are shipping and handling. The vials will be shipped in liquid nitrogen tanks. Delivery is requested within 60 days of receipt of order. The related federal contract opportunity is solicitation number 75N95023Q00551 from the Department of Health and Human Services National Institutes of Health National Institute on Drug Abuse seeking cryopreserved human, mouse, and rat hepatocytes. No further details are provided on pricing, responses, or awards.

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Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

PURCHASE DESCRIPTION

1. Statement of Need and Purpose: Item necessary to estimate the metabolic stability of compounds in hepatocytes

2. Background Information and Objective: To perform drug metabolism experiments it is necessary to incubate the compounds of interest with liver metabolizing enzymes.

Usually, we use liver microsomal fractions for the metabolism studies, however, for the Malaria project, it is necessary to use more complex systems due to the nature of the compounds with show very low clearance. The objective of these hepatocytes is to incubate compounds from the malaria project and understand their metabolism in a more long lasting incubation system, such as cryopreserved hepatocytes.

3. Generic Name of Product: CryostaX Cryopreserved Human Hepatocytes; CryostaX Cryopreserved Male Mouse Hepatocytes; CryostaX Cryopreserved Rat Hepatocytes;

Shipping, Handling.

4. Purchase Description:

(1) CryostaX Cryopreserved Human Hepatocytes; Sekisui Xenotech, LLC.; Catalog number HPCH10; 40 units

(2) CryostaX Cryopreserved Male Mouse Hepatocytes; Sekisui Xenotech, LLC.; Catalog number MPCH1000; 40 units

(3) CryostaX Cryopreserved Rat Hepatocytes Sekisui Xenotech, LLC.; Catalog number RPCH1000; 40 units

(4) Shipping,

(5) Handling

5. Salient characteristics: Vials shipped in liquid nitrogen tanks.

6. Quantity: Please see purchase description. 40 vials of mouse, rat, and human cryopreserved hepatocytes. Shipping and handling.

7. Delivery Date: 60 days after receipt

8. Period of Performance: Not applicable

Version 11-30-2016-1 FAR Part 11—Describing Agency Needs

9. Option(s): Not applicable

File details come from the government source that posted it. Updated .