A15 - Product Specifications - Standards.pdf
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- 00HCUGDK-2020-41605
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ISOTOPE LABELING FOR INTERNAL STANDARDS
OPEN MARKET PLACE BID REQUIREMENTS
4-METHYLHIPPURIC ACID-13C6
13C
13C 13C
13C
13C
13C
NH
O
OH
O
Chemical Formula: C4
13C6H11NO3
Molecular Weight: 199.16 g/mol
N-ACETYL-S-(3-HYDROXYPROPYL)-L-CYSTEINE-13C5
H 13C
HN
13C
13CH3
OH
13C H2 13C
SHO
O
O
Chemical Formula: C3
13C5H15NO4S
Molecular Weight: 226.23 g/mol
N-ACETYL-S-(2,2-DICHLOROVINYL)-L-CYSTEINE-13C3,15N,D3
13C
H15N CD3
OH
13C
O
O
H2 13C
S
H
Cl
Cl
Chemical Formula: C4 13C3H6D3Cl2
15NO3S
Molecular Weight: 265.10 g/mol
N-ACETYL-S-(2-CARBAMOYL-2-HYDROXYETHYL)-L-CYSTEINE-13C3
13C
HN
OH
13C
O
O
H2 13C
S
OH
H2N
O
Chemical Formula: C5 13C3H14N2O5S
Molecular Weight: 253.25 g/mol
N-ACETYL-S-(3-HYDROXYPROPYL-1-METHYL)-L-CYSTEINE-13C3
13C
HN
OH
13C
O
O
H2 13C
SHO
Chemical Formula: C6
13C3H17NO4S
Molecular Weight: 238.28
CH3
g/mol
N-ACETYL-S-(3,4-DIHYDROXYBUTYL)-L-CYSTEINE-13C4
13C
HN
13C
OH
13C
O
O
H2 13C
S
OH
HO
Chemical Formula: C5
13C4H17NO5S
Molecular Weight: 255.27 g/mol
N-ACETYL-S-(6-HYDROXY-2,4-CYCLOHEXADIEN-1-YL)-L-CYSTEINE
Chemical Formula: C11H14NO4S
Molecular Weight: 256 g/mol
CHEMICAL AND ISOTOPIC PURITY REQUIREMENTS
1. 4-Methylhippuric acid –13C6. Isotopic purity and chemical purity equal to or greater than 98%. Need 25-50 mg.
2. N-Acetyl-S-(3-hydroxypropyl)-L-cysteine-13C5. Isotopic purity and chemical purity equal to or greater than 98%.
Need 25-50 mg.
3. N-Acetyl-S-(2,2-dichlorovinyl)-L-cysteine-13C3,15N,D3. Isotopic purity and chemical purity equal to or greater than 98%. Need 25-50 mg.
4. N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine-13C3. Isotopic purity and chemical purity equal to or greater than 98%. Need 25-50 mg.
5. N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine-13C3. Isotopic purity and chemical purity equal to or greater than 98%. Need 25-50 mg.
6. N-Acetyl-S-(3,4-dihydroxybutyl)-L-cysteine-13C4. Isotopic purity and chemical purity equal to or greater than 98%.
Need 25-50 mg.
7. N-Acetyl-S-(6-hydroxy-2,4-cyclohexadien-1-yl)-L-cysteine. Chemical purity greater than 95%. Mixture of diastereomers is acceptable if it is properly documented. Need 50-75 mg.
| Isotope labeling for Internal standards |
| 4-methylhippuric acid-13C6 |
| N-Acetyl-s-(3-hydroxypropyl)-L-cysteine-13c5 |
| N-acetyl-s-(2,2-dichlorovinyl)-L-cysteine-13C3,15N,D3 |
| N-Acetyl-S-(2-carbamoyl-2-hydroxyethyl)-L-cysteine-13C3 |
| N-Acetyl-S-(3-hydroxypropyl-1-methyl)-L-cysteine-13C3 |
| N-Acetyl-s-(3,4-dihydroxybutyl)-L-Cysteine-13C4 |
| N-Acetyl-S-(6-hydroxy-2,4-cyclohexadien-1-yl)-L-cysteine |
| Chemical and isotopic purity requirements |
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