UNSPSC 51373305: Acetaminophen/butalbital/caffeine/codeine

Commodity

Code facts

NIGP codes
1

UNSPSC codes and definitions come from the UN Development Programme (managed by GS1 US), and state and local contract opportunities from the governments' procurement sites.

NIGP codes for 51373305

Definition

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF), which falls under VA Drug Class CN101. This VA Drug Class (CN101) classifies this compound as belonging to the group OPIOID ANALGESICS.

The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate.

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The European Medicines Agency schedules Acetaminophen in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB09611MIG. The World Health Organization schedules acetaminophen in its Anatomical Therapeutic Chemical (ATC) Classification.

The second component of this combination drug is a barbiturate with the molecular formula C11H16N2O3, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier KHS0AZ4JVK, chemically known as 2,4,6(1h,3h,5h)-pyrimidinetrione, 5-(2-methylpropyl)-5-(2-propenyl)- but more generally known as butalbital, which bears U.S. National Institutes of Health Compound Identifier 2481. Butalbital most often comes in base and sodium forms.

The European Medicines Agency schedules Butalbital in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB05999MIG. The term BUTALBITAL is an International Non-Proprietary Name or INN (see World Health Organization INN reference publication, Volume 23, No. 10 1969, List 9).

The third component of this combination drug is a cns stimulant and bioactive food component with the molecular formula C8H10N4O2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 3G6A5W338E, chemically known as 1,3,7-trimethylxanthine but more generally known as caffeine, which bears U.S. National Institutes of Health Compound Identifier 2519. caffeine comes in many forms, including base, benzoate, benzoate sodium, bromide, citrate, hydrobromide, hydrochloride, hydroiodide, monohydrate, salicylate, sodium benzoate, sodium benzoicum, and sodium salicylate.

The European Medicines Agency schedules Caffeine in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB13146MIG. The World Health Organization schedules caffeine in its Anatomical Therapeutic Chemical (ATC) Classification.

The fourth component of this combination drug is an opiate with the molecular formula C18H21NO3.H2O, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier Q830PW7520, chemically known as codeine, sulfate but more generally known as codeine, which bears U.S. National Institutes of Health Compound Identifier 223652. The European Medicines Agency schedules Codeine in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB13424MIG.

The World Health Organization schedules codeine in its Anatomical Therapeutic Chemical (ATC) Classification.

About UNSPSC 51373305

UNSPSC 51373305 Acetaminophen/butalbital/caffeine/codeine is a Commodity code that does not reflect recent state and local procurement activity under its nominal scope. The three most recent opportunities tagged to this code involve naloxone and drug deactivation systems, a direct-to-manufacturer prescription program RFI, and generic multi-source pharmaceuticals and OTC products through a cooperative purchasing vehicle—none of which are acetaminophen-based combination analgesics. The code shows a mismatch between its specific drug formulation and the broader pharmaceutical procurement being conducted by state and local agencies.

Recent activity involves health departments, state HHS commissions, and cooperative purchasing alliances sourcing emergency medical supplies, pharmacy benefit management infrastructure, and generic pharmaceutical inventories across Florida, Texas, and Minnesota. Seminole County, Florida issued IFB 60459723LAS in June 2026 seeking 1,900 units of naloxone and 800 safe drug deactivation systems annually with quarterly deliveries (due July 26, 2023), while the Texas Health and Human Services Commission posted RFI HHS0017013 in April 2026 to gather vendor capabilities on direct-to-manufacturer prescription fulfillment models. The Minnesota Multistate Cooperative Purchasing Alliance (MMCAP) issued RFP S1070000015802 in January 2026 for generic multi-source pharmaceuticals and OTC products with proposals due March 26, 2026, distributed through AmerisourceBergen, Cardinal Health, and Morris & Dickson with award effective July 1, 2026. The code sees no clear current relevance to acetaminophen-butalbital-caffeine-codeine procurement at the state or local level based on recent solicitations.

Quick answers

What is UNSPSC 51373305?

UNSPSC 51373305 is Acetaminophen/butalbital/caffeine/codeine, a commodity in UNSPSC 51000000, Pharmaceutical Products incl. Contraceptives and Vaccines.

Which NIGP codes match UNSPSC 51373305?

UNSPSC 51373305 maps to 1 NIGP code, 26928 Central Nervous System Agents (Including: Analegsic, Anticonvulsant, Antidepressant, Antihistamine, Antipsychotic and Sedative).

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