UNSPSC 51372114: Codeine hydrochloride dihydrate

This classification denotes an opiate with the molecular formula C18H21NO3.ClH.2H2O, a preparation that US FDA regulates as an active ingredient or moiety under Unique Ingredient Identifier NTZ53GG7XN, chemically known as morphinan-6-alpha-ol, 7,8-didehydro-4,5-alpha-epoxy-3-methoxy-17-methyl-, hydrochloride but more generally known as codeine hydrochloride, which bears US NIH Compound Identifier 5359615. European Medicines Agency schedules Codeine hydrochloride in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB01405MIG.

Most nations, for tariff and trade purposes, schedule codeine hydrochloride dihydrate under HS 29391100. SMILES: CN1CC[C@]23C4C5CCC(C4O[C@H]2[C@H](C=C[C@H]3[C@H]1C5)O)OC.O.O.CL.

UNSPSC 51372114 Codeine hydrochloride dihydrate is a Commodity code that nominally identifies a specific pharmaceutical product, but state and local government purchasing under this code spans a broader set of pharmaceutical procurement and pharmacy benefit management initiatives rather than codeine-specific acquisitions. Recent opportunities posted under or near this code show state and local agencies sourcing generic multi-source pharmaceuticals, over-the-counter products, naloxone and drug deactivation systems, and direct-to-manufacturer prescription programs to support community health, emergency response, and employee health benefit delivery. Soliciting bodies include county health departments (Seminole County, Florida), state human services commissions (Texas Health and Human Services Commission), and multi-state cooperative purchasing alliances (Minnesota Multistate Cooperative Purchasing Alliance serving state and local government facilities across Minnesota and Oregon). The issuing bodies' mix reflects both direct county procurement and state-administered cooperative purchasing vehicles that extend purchasing authority across multiple participating jurisdictions.

Geographic activity centers in Florida, Texas, and Minnesota as of the most recent postings in 2026. Representative recent opportunities include Seminole County's IFB60459723LAS (due July 26, 2023, seeking 1,900 units of naloxone and 800 drug deactivation systems annually through quarterly deliveries), the Texas Health and Human Services Commission's RFI HHS0017013 (posted April 3, 2026, exploring direct-to-manufacturer prescription fulfillment capabilities), and the Minnesota Multistate Cooperative Purchasing Alliance's RFP S1070000015802 (due March 26, 2026, establishing multiple contracts for generic pharmaceuticals and OTC products across participating jurisdictions with awarded vendors effective July 1, 2026). The Minnesota cooperative procurement emphasizes pricing competitiveness (75 percent evaluation weight), cGMP and Drug Supply Chain Security Act compliance, and multi-wholesaler distribution through AmerisourceBergen, Cardinal Health, and Morris & Dickson. None of the recent opportunities specify set-aside designations for disadvantaged enterprises.