UNSPSC 51351803: Esterified estrogen

This classification denotes an estrogen with the molecular formula C18H24O2, a preparation that US FDA regulates as an active ingredient or moiety under Unique Ingredient Identifier 4TI98Z838E, chemically known as estra-1,3,5(10)-triene-3,17-diol (17.beta.)- but generally known as esterified estrogens, which bears US NIH Compound Identifier 450. European Medicines Agency schedules esterified estrogens in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB13723MIG. The term ESTRADIOL is an International Non-Proprietary Name.

World Health Organization schedules esterified estrogens in its Anatomical Therapeutic Chemical (ATC) Classification. SMILES: OC1C2(C(C3C(CC2)c2c(CC3)cc(O)cc2)CC1)C.

UNSPSC 51351803 Esterified estrogen is a Commodity code for pharmaceutical active pharmaceutical ingredients and finished-form hormone-replacement medications. State and local governments procure esterified estrogen products primarily through cooperative purchasing alliances and multistate purchasing vehicles that consolidate demand across participating jurisdictions and their healthcare facilities, rather than through direct individual agency solicitations. The procurement typically involves establishing blanket or term contracts with pharmaceutical manufacturers and distributors who meet cGMP certification, FDA compliance, Drug Supply Chain Security Act requirements, and specified insurance thresholds including $5 million commercial general liability coverage per occurrence.

The Minnesota Multistate Cooperative Purchasing Alliance (MMCAP), administered by the Minnesota Department of Administration's Office of State Procurement, issued a Request for Proposal in January 2026 (S1070000015802) to establish multiple contracts for generic multi-source pharmaceuticals and OTC products across participating state and local government facilities, including Oregon. The RFP, due March 26, 2026, sought manufacturers to supply esterified estrogen and related hormone-replacement products with detailed product information including National Drug Codes, SKUs, UPCs, generic descriptions, strength, dosage form, and manufacturing locations. Vendors must maintain contractual relationships with at least two of three authorized wholesalers (AmerisourceBergen Drug Corporation, Cardinal Health, and Morris & Dickson Co., LLC), comply with pricing formats including flat price, net price, or WAC-minus structures, and agree to a 3 percent administrative fee. The contract term is two years for new responders with optional extensions, effective July 1, 2026, with specific award values not disclosed in solicitation materials. MMCAP reserved the right to make sole, dual, or multi-awards based on therapeutic considerations, product availability, and member-specific needs.