UNSPSC 51314389: Acetaminophen/dextromethorphan/doxylamine/pseudoephedrine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF) which falls under VA Drug Class RE506. This VA Drug Class (RE506) classifies this compound as belonging to the group ANTIHISTAMINE/DECONGESTANT/ANTITUSSIVE/ANALGESIC.

The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate.

UNSPSC 51314389 Acetaminophen/dextromethorphan/doxylamine/pseudoephedrine is a Commodity code that in practice encompasses naloxone and safe drug deactivation systems, generic multi-source pharmaceuticals, and over-the-counter products procured for community health and pharmacy benefit programs by state and local public health agencies. State and local governments buy these products through direct procurement vehicles and cooperative purchasing alliances to support emergency response, pharmacy benefit management, and public health infrastructure. Issuing bodies include county health departments (Seminole County, Florida), state health and human services commissions (Texas HHS), and multistate cooperative purchasing organizations (Minnesota Multistate Cooperative Purchasing Alliance, serving participating state and local facilities including Oregon). The scope encompasses both emergency response pharmaceuticals (naloxone for opioid reversal) and routine pharmacy benefit supply chains, with vendors required to maintain current Good Manufacturing Practices certification, Drug Supply Chain Security Act compliance, and relationships with authorized drug wholesalers.

Recent activity reflects three distinct procurement approaches. Seminole County, Florida issued IFB 60459723LAS (due July 26, 2023) seeking annual procurement of 1,900 units of naloxone and 800 safe drug deactivation systems with quarterly deliveries to its Community Health Building. The Texas HHS Commission posted RFI HHS0017013 (April 3, 2026) to gather market intelligence on direct-to-manufacturer prescription programs that would bypass traditional pharmacy benefit managers and wholesalers. The Minnesota Multistate Cooperative Purchasing Alliance (MMCAP) issued RFP S1070000015802 (due March 26, 2026) for generic multi-source pharmaceuticals and OTC products through authorized wholesalers including AmerisourceBergen, Cardinal Health, and Morris & Dickson, with a contract term starting July 1, 2026 and a 3 percent administrative fee required. Recent opportunities cluster in Florida and the upper Midwest, with cooperative purchasing models spanning multiple states and localities.