UNSPSC 51314388: Acetaminophen/dextromethorphan/doxylamine/ephedrine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF) which falls under VA Drug Class RE506. This VA Drug Class (RE506) classifies this compound as belonging to the group ANTIHISTAMINE/DECONGESTANT/ANTITUSSIVE/ANALGESIC.

The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate.

UNSPSC 51314388 Acetaminophen/dextromethorphan/doxylamine/ephedrine is a Commodity code covering pharmaceutical products, though recent state and local solicitations tagged with this code diverge significantly from its nominal scope. The opportunities actually being procured include naloxone and drug deactivation systems, generic multi-source pharmaceuticals and over-the-counter products distributed through established wholesaler networks, and exploratory direct-to-manufacturer prescription programs. State and local issuing bodies soliciting under or near this code include county health departments (Seminole County, Florida), state health and human services commissions (Texas HHS Commission), and multistate cooperative purchasing alliances (Minnesota Multistate Cooperative Purchasing Alliance, serving Minnesota and Oregon). The work involves supply of finished pharmaceutical products with established National Drug Codes, compliance with Good Manufacturing Practices and Drug Supply Chain Security Act requirements, and fulfillment through authorized wholesaler networks or direct manufacturer relationships.

Recent activity concentrates in Florida and the Upper Midwest. Seminole County posted IFB 60459723LAS on June 30, 2026, seeking 1,900 units of naloxone and 800 safe drug deactivation systems annually with quarterly deliveries to the Seminole County Community Health Building and a response deadline of July 26, 2023. The Minnesota Multistate Cooperative Purchasing Alliance issued RFP S1070000015802 on January 20, 2026, establishing multiple contracts for generic pharmaceuticals and OTC products through authorized wholesalers AmerisourceBergen (Cencora), Cardinal Health, and Morris & Dickson, with proposals due March 26, 2026 and pricing weighted at 75 percent of evaluation criteria. The Texas HHS Commission posted Request for Information HHS0017013 on April 3, 2026, to explore vendor capabilities for a direct-to-manufacturer prescription program serving state agencies and self-insured health plans, representing exploratory procurement ahead of formal contracting. Neither the Seminole County bid nor the MMCAP RFP specifies explicit set-aside designations or disadvantaged-enterprise restrictions.