UNSPSC 51314386: Acetaminophen/dextromethorphan/diphenhydramine/pseudoephedrine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF) which falls under VA Drug Class RE506. This VA Drug Class (RE506) classifies this compound as belonging to the group ANTIHISTAMINE/DECONGESTANT/ANTITUSSIVE/ANALGESIC.

The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate.

UNSPSC 51314386 Acetaminophen/dextromethorphan/diphenhydramine/pseudoephedrine is a Commodity code that, based on recent state and local opportunities, encompasses procurement of generic multi-source pharmaceuticals and over-the-counter (OTC) products distributed through state and local health systems, community health initiatives, and pharmacy benefit programs. State and local governments soliciting under this code include county health departments, state health and human services agencies, and cooperative purchasing alliances that aggregate demand across multiple jurisdictions. The work involves sourcing compliance-certified pharmaceutical manufacturers capable of supplying NDC-coded products through authorized wholesalers, meeting cGMP and Drug Supply Chain Security Act (DSCSA) standards, and delivering products with specified shelf-life and expiration requirements to health facilities and distribution points.

Recent activity spans Florida, Texas, and the upper Midwest multi-state region. The Minnesota Multistate Cooperative Purchasing Alliance (MMCAP), administered by the Minnesota Department of Administration's Office of State Procurement, issued RFP S1070000015802 on January 20, 2026 (due March 26, 2026) for generic multi-source pharmaceuticals and OTC products to be distributed across participating state and local facilities in Minnesota and Oregon, with awarded vendors to be provided to AmerisourceBergen Drug Corporation (Cencora), Cardinal Health, and Morris & Dickson Co., LLC by May 15, 2026. Seminole County, Florida posted IFB 60459723LAS in June 2026 (due July 26, 2023) to procure 1,900 units of naloxone and 800 safe drug deactivation systems annually with quarterly deliveries to the Seminole County Community Health Building. The Texas Health and Human Services Commission issued RFI HHS0017013 in April 2026 as preliminary market intelligence for a Therapeutic Pharmacy Initiative Direct-to-Manufacturer Prescriptions program, seeking vendor capabilities for direct contracting with self-insured employer and state agency health plans outside traditional pharmacy benefit manager arrangements.