UNSPSC 51314333: Chlorpheniramine/dextromethorphan/phenylephrine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF), which falls under VA Drug Class RE502. This VA Drug Class (RE502) classifies this compound as belonging to the group ANTIHISTAMINE/DECONGESTANT/ANTITUSSIVE.

UNSPSC 51314333 Chlorpheniramine/dextromethorphan/phenylephrine is a Commodity code that covers branded and generic combination cold and allergy medications in tablet, liquid, and suspension forms. Recent state and local solicitations tagged under this code show little alignment with the code's nominal scope — the opportunities posted are for naloxone and drug deactivation systems (opioid overdose reversal), direct-to-manufacturer prescription programs, and multi-source generic pharmaceuticals and OTC products distributed through cooperative purchasing agreements. The mismatch suggests either classification drift in how procurement offices tag pharmaceutical purchases or that the code serves as a catch-all for miscellaneous pharmaceutical acquisitions. Issuing bodies include state health and human services agencies, county health departments, and cooperative purchasing alliances spanning multiple states and local jurisdictions.

Recent activity appears in Florida, Texas, and Minnesota. Seminole County, Florida released an IFB for naloxone and drug deactivation systems (1,900 units of naloxone and 800 safe drug deactivation systems annually) with a response deadline of July 26, 2023. The Texas Health and Human Services Commission issued an RFI in April 2026 to gather market intelligence on direct-to-manufacturer prescription fulfillment capabilities prior to formal solicitation. The Minnesota Multistate Cooperative Purchasing Alliance (MMCAP) issued an RFP in January 2026 for generic multi-source pharmaceuticals and OTC products, with proposals due March 26, 2026 and contract effectiveness July 1, 2026. The MMCAP procurement is the most representative of large-scale state and local activity under this code tier, requiring vendors to supply through three authorized wholesalers (AmerisourceBergen Drug Corporation, Cardinal Health, and Morris & Dickson Co.), maintain cGMP and Drug Supply Chain Security Act compliance, and accept a 3 percent administrative fee on all purchases.