UNSPSC 51285200: Dihydrofolate reductase inhibitor antibacterials

This classification denotes substances that inhibit dihydrofolate reductase, an enzyme which holds sway over cell division; these instant substances can, under certain circumstances, prevent cells from dividing and thus prevent spread of infection or even malignant cancer, substances that are therefore called dihydrofolate reductase inhibitors, this the term DIHYDROFOLATE REDUCTASE INHIBITOR ANTIBACTERIALS. This classification aims at the power of such substances to stay the proliferation of bacteria, which rely in part on dihydrofolate reductase to multiply.

UNSPSC 51285200 Dihydrofolate reductase inhibitor antibacterials, a Class code, covers pharmaceutical procurement by state and local health departments and county governments for broad-spectrum antibiotics used in public health response and community health programs. State and local bodies soliciting under this code buy specific antibiotic formulations—doxycycline hyclate and ciprofloxacin hydrochloride tablets—through both direct procurement and cooperative purchasing vehicles such as MMCAP Infuse. The work involves warehouse supply agreements with pharmaceutical distributors, typically structured as multi-year contracts with renewal options and quarterly or standing order delivery schedules to health facilities and community health buildings.

Illinois Department of Public Health and Seminole County, Florida represent the issuing bodies active under this code in recent months. The Illinois procurement (Solicitation 26482DPHPREPDB53392, awarded August 2026 to Chartwell Rx LLC via IFB through the MMCAP Infuse consortium) supplied doxycycline hyclate 100mg and ciprofloxacin hydrochloride 500mg tablets under a $2,999,999.11 contract over three years including renewals. Seminole County, Florida posted an IFB (IFB60459723LAS, due July 26, 2023) for naloxone and safe drug deactivation systems—a procurement tangentially related to the code's nominal scope. Geographic activity centers on the Southeast and Midwest, with the most recent substantive solicitation originating in Illinois through a regional cooperative purchasing framework and representing state-level health department demand.