UNSPSC 51162307: Acetaminophen/caffeine/guaifenesin/phenylephrine

This classification denotes a combination drug defined by the U.S. Department of Veterans Affairs in its (VA's) National Drug File (NDF), which falls under VA Drug Class RE599. This VA Drug Class (RE599) classifies this compound as belonging to the group COLD REMEDIES, OTHER.

The first component of this combination drug is an analgesic and antipyretic with the molecular formula C8H9NO2, a preparation that US FDA recognizes as an active ingredient or moiety under Unique Ingredient Identifier 362O9ITL9D, chemically known as n-(4-hydroxyphenyl)acetamide but more generally known as acetaminophen, which bears U.S. National Institutes of Health Compound Identifier 1983. Acetaminophen comes in many forms, including base, acetate, cysteine, cysteinylglycine, di-methyl derivative, glucuronide, glutathione, hemisuccinate, mercapturate, and sulfate.

UNSPSC 51162307 Acetaminophen/caffeine/guaifenesin/phenylephrine is a Commodity code that nominally specifies a single pharmaceutical formulation, but recent state and local activity under this code does not align with the narrow product specification. The two recent opportunities posted under this code involve procurement of naloxone and drug deactivation systems (Seminole County, Florida) and a multistate cooperative purchasing agreement for generic pharmaceuticals and OTC products across multiple therapeutic categories (Minnesota Multistate Cooperative Purchasing Alliance). Neither solicitation targets the specific acetaminophen/caffeine/guaifenesin/phenylephrine combination named in the code, indicating a significant mismatch between the code's nominal scope and what state and local buyers are actually purchasing under it. This code shows limited relevant recent activity aligned with its stated pharmaceutical formulation.

The two posted opportunities span a county health department and a multistate cooperative purchasing vehicle administered by a state procurement office. Seminole County, Florida released IFB60459723LAS on June 30, 2026, seeking 1,900 units of naloxone and 800 safe drug deactivation systems annually with quarterly deliveries, response deadline July 26, 2023. The Minnesota Department of Administration's Office of State Procurement issued RFP S1070000015802 through MMCAP on January 20, 2026, to establish multiple contracts for generic pharmaceuticals and OTC products across participating state and local government facilities in Minnesota and Oregon, with proposals due March 26, 2026. Given the code's specificity and the misalignment between the code definition and actual solicitation scope, this category warrants close attention to how issuing bodies are tagging pharmaceutical procurements — pursuit decisions should verify whether opportunities are genuinely targeted at the acetaminophen/caffeine/guaifenesin/phenylephrine combination or whether the code is being used as a catch-all for broader pharmaceutical categories.