UNSPSC 51143800: Combination CNS stimulants

This classification denotes combination drugs and preparations that stimulate the main information-processing organs of the nervous system, consisting of the brain, spinal cord, and meninges, or the Central Nervous System or CNS, hence the term CNS STIMULANTS. Typical combination CNS stimulant constituents are amphetamine and caffeine.

UNSPSC 51143800 Combination CNS stimulants is a Class code under which state and local governments procure pharmaceutical products and drug-management systems supporting public health and emergency response initiatives. Recent solicitations show that the code captures purchases of naloxone (opioid reversal medication), safe drug deactivation systems, and generic multi-source pharmaceuticals distributed through state and local health, emergency services, and benefits programs. Issuing bodies include county health departments, state health and human services commissions, and multistate cooperative purchasing alliances. The scope spans both emergency-response supplies (naloxone kits for community health distribution) and ongoing pharmaceutical benefit management for state employee and beneficiary populations, with vendors typically required to meet FDA compliance, Good Manufacturing Practices certification, Drug Supply Chain Security Act adherence, and detailed insurance requirements including workers' compensation and commercial general liability coverage.

Activity appears concentrated in the Southeast and Upper Midwest. Seminole County, Florida issued IFB60459723LAS in June 2026 seeking 1,900 units of naloxone and 800 safe drug deactivation systems annually with quarterly deliveries to the Seminole County Community Health Building (response deadline July 26, 2023). The Texas Health and Human Services Commission posted RFI HHS0017013 on April 3, 2026 to gather vendor capabilities for a Direct-to-Manufacturer Prescriptions program targeting direct contracting with pharmaceutical manufacturers outside traditional pharmacy benefit manager relationships. The Minnesota Multistate Cooperative Purchasing Alliance (MMCAP), administered by the Minnesota Department of Administration's Office of State Procurement, issued an RFP for generic multi-source pharmaceuticals and OTC products effective July 1, 2026 through three authorized wholesalers (AmerisourceBergen, Cardinal Health, Morris & Dickson), with proposals due March 26, 2026 and evaluation weighted 75 percent on price competitiveness. MMCAP contracts extend to participating jurisdictions including Oregon.