UNSPSC 51111650: Pemetrexed

This classification denotes a thymidylate synthase inhibitor and folate antagonist with the molecular formula C20H21N5O6, a preparation that US FDA regulates as an active ingredient or moiety under Unique Ingredient Identifier 04Q9AIZ7NO, chemically known as n-(4-(2-(2-amino-3,4-dihydro-4-oxo-7h-pyrrolo(2,3-d)pyrimdin-5-yl)ethyl)benzoyl)glutamic acid but generally known as pemetrexed, which bears US NIH Compound Identifier 60843. European Medicines Agency schedules Pemetrexed in its eXtended EudraVigilance Medicinal Product Dictionary or XEVMPD under Index SUB09655MIG.

UNSPSC 51111650 Pemetrexed is a Commodity code naming a specific chemotherapy drug purchased by state and local health and human services agencies to support pharmacy benefit programs and patient treatment protocols. State and local procurement under this code focuses on securing pharmaceutical supply through various contracting models — direct-to-manufacturer relationships, group purchasing organization (GPO) arrangements, pharmacy benefit manager (PBM) channels, and wholesaler networks. The issuing bodies are primarily state health and human services departments managing Medicaid, employee health plans, and state agency pharmacy benefits, alongside county health systems and public health agencies that operate or reimburse pharmacy services.

Texas Health and Human Services Commission posted Request for Information (RFI) HHS0017013 in March 2026 to explore vendor capabilities for a Therapeutic Pharmacy Initiative Direct-to-Manufacturer Prescriptions program, with response due April 3, 2026. The RFI seeks vendors' experience with direct contracting for self-insured employers and government health plans, flexibility on negotiated net pricing models without rebates, and ability to implement value-based or outcomes-based agreements. This exploratory procurement step precedes a formal RFP and reflects the state's effort to restructure pharmaceutical procurement outside traditional PBM and GPO intermediaries. No award value, budget allocation, or set-aside designation is identified at the RFI stage. Texas currently represents the most recent visible activity under this code; geographic spread and issuing-body concentration across other states are not supported by the available source material.