Vaccine Safety Datalink (VSD)

The Vaccine Safety Datalink (VSD) is a multiple-award Indefinite Delivery/Indefinite Quantity (IDIQ) contract vehicle managed by the Centers for Disease Control and Prevention's Immunization Safety Office to support comprehensive vaccine safety monitoring and research. The contract enables the CDC to issue task orders across three primary technical areas: vaccine safety project infrastructure activities, active surveillance and monitoring, and epidemiological studies and evaluations. Contractors provide critical data infrastructure and expertise to evaluate adverse events following immunizations, develop vaccine safety methodologies, and support public health priorities related to vaccine research.

Task orders under this vehicle are consistently awarded to established healthcare organizations and research institutions, with values ranging from a few thousand dollars to nearly $30 million. Prime contractors frequently include Kaiser Permanente, HealthPartners Institute, Indiana University, Harvard Pilgrim Health Care, Marshfield Clinic, Denver Health, and Ochin, Inc. The task orders are typically cost-reimbursement or cost-no-fee contracts with performance periods extending up to five years, culminating in September 2027. All task orders to date have been awarded without specific set-aside designations, and performance is required within the United States. The funding agency, the Centers for Disease Control and Prevention, uses this contract vehicle to conduct post-licensure vaccine safety surveillance, monitor health outcomes of vaccinated populations, and rapidly respond to emerging vaccine safety concerns.