Pharmacology and Toxicology for Therapeutics Program (PTTP)
Active Master IDIQ Awarded
- Federal agency
-
National Institutes of Health
- Awardees
- 2
- Task orders
- 18
- Obligated
- $18,726,239
Vehicle facts
- Opportunity
-
- NIHNINDS1601 Solicitation number
- Agency
-
- National Institutes of Health Department of Health and Human Services
- Combined task order value
-
- $18,726,239 Current, with exercised options
- $25,620,349 Potential, with all options
- Last date to order 92% complete
- Shared ceiling 11% used
- $174,470,000.00
IDV award and task order details come from SAM.gov/FPDS.
About this vehicle
The National Institutes of Health, through the National Institute of Neurological Diseases and Stroke, awarded the Pharmacology and Toxicology for Therapeutics Program, a Master IDIQ for pharmacokinetic, toxicology, and safety assessment of promising therapeutic candidates. Orders may be placed through September 12, 2027, with 10 months and 1 week of ordering authority remaining. No set-aside has been used on any of the 18 task orders, and the vehicle carries a shared ceiling of $174.47 million.
The vehicle was established September 13, 2016, and the most recent task order was awarded July 3, 2023. Annual order counts were 2 in 2018, 5 in 2019, 2 in 2020, 2 in 2022, and 1 in 2023, with no orders recorded in 2021 or after mid-2023. Task orders have obligated $18.7 million, or 73% of their $25.6 million combined potential value. The source identifies no predecessor or successor vehicle.
Orders buy rodent and non-rodent pharmacokinetic studies, GLP and IND-enabling toxicology, dog dose-range finding and 28-day dog pharmacokinetic and clinical chemistry assessments, and management and operations support. Recent orders also cover HEAL Initiative rodent and non-rodent pharmacokinetic work.
Sri International holds 15 of 18 orders with $23.8 million in combined potential value. Southern Research Institute holds the other three orders, worth $1.8 million combined. Activity is concentrated in one prime.
The National Institute of Neurological Disorders and Stroke places 11 orders ($15.4 million combined potential value), and the National Institute on Drug Abuse places 7 orders ($10.2 million). Both customers sit within NIH.
Recent order ceilings range from $142,909.00 to $7,323,160.93, the latter for SRI TO 13, continuous rodent and non-rodent pharmacokinetic assessments. Pricing is mostly cost-plus-fixed-fee, with some labor-hour and firm-fixed-price orders. Periods of performance in the recent set run from about eight months to ten years.
Description
The National Institute of Neurological Diseases and Stroke (NINDS), National Institutes of Health (NIH) has awarded a Master IDIQ for services to assess the pharmacokinetics, toxicology and safety of promising candidates to support their eventual use as therapeutics.
IDV awards
| Awardee | IDV award | Awarded |
|---|---|---|
| Southern Research Institute | HHSN271201600007I | |
| Sri International | HHSN271201600006I |
Latest task orders
Show all 18
Top awardees by obligations
| Rank | Awardee | Obligated | Share |
|---|---|---|---|
| 1 | Sri International | $17,062,451 | 91% |
| 2 | Southern Research Institute | $1,663,788 | 9% |
Top funding agencies by obligations
| Rank | Funding agency | Obligated | Share |
|---|---|---|---|
| 1 | Department of Health and Human Services | $18,726,239 | 100% |
Obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2026 | -$225,506 |
| FY2025 | -$141,054 |
| FY2024 | $1,149,075 |
| FY2023 | $1,760,450 |
| FY2022 | $1,868,897 |
| FY2021 | $1,198,143 |
| FY2020 | $4,445,852 |
| FY2019 | $4,517,667 |
| FY2018 | $2,854,746 |
| FY2017 | $1,089,034 |
| FY2016 | $208,935 |
Show all 11
Quick answers
What is the PTTP contract vehicle?
Pharmacology and Toxicology for Therapeutics Program (PTTP) is an indefinite delivery, indefinite quantity (IDIQ) contract vehicle run by National Institutes of Health (Department of Health and Human Services), awarded on September 13, 2016.
Which companies hold PTTP?
2 companies hold PTTP's IDV awards, one each. The latest went to Southern Research Institute on September 13, 2016. The awardees whose task orders obligated the most are Sri International and Southern Research Institute.
How much has been spent through PTTP?
18 task orders have been placed under PTTP, obligating $18,726,239.
What is the shared ceiling of PTTP?
PTTP's shared ceiling is $174,470,000; its task orders have used 11% of it.
Which agencies use PTTP the most?
The departments whose task orders under PTTP obligated the most are Department of Health and Human Services ($18,726,239).
How much was obligated through PTTP in fiscal year 2025?
Task orders under PTTP obligated -$141,054 in fiscal year 2025.
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