Pharmacology and Toxicology for Neurotherapeutics Program (PTNP)
Ended Master IDIQ Awarded
- Federal agency
-
National Institutes of Health
- Awardees
- 2
- Task orders
- 41
- Obligated
- $14,483,111
Vehicle facts
- Opportunity
-
- NIHNIMH2010023 Solicitation number
- Agency
-
- National Institutes of Health Department of Health and Human Services
- Combined task order value
- $14,428,077 Current and potential, with all options
- Last date to order 100% complete
- Shared ceiling 19% used
- $75,000,000.00
IDV award and task order details come from SAM.gov/FPDS.
About this vehicle
The National Institute of Mental Health established this Master IDIQ on September 13, 2011 for in vitro and in vivo preclinical pharmacology and safety (ADMET) studies supporting development of drugs for nervous system disorders; ordering closed on September 12, 2016 and the vehicle is no longer active.
The vehicle spans 41 task orders awarded over five years, with ordering momentum peaking at nine orders in 2015 before declining to seven in 2016. Combined potential value stands at $14.4 million, with $14.5 million obligated—exceeding the stated shared ceiling of $75 million. Work awarded includes rodent and non-rodent pharmacokinetic assessment, brain-level determination studies, dose-range finding toxicology, in vivo metabolite identification, IND-enabling studies, and administrative program support. Most orders used cost-plus-fixed-fee and cost-plus-award-fee pricing structures.
Competition concentrated sharply between two primes: Sri International captured 24 orders valued at $8.8 million combined potential, while Southern Research Institute held 17 orders at $5.6 million combined potential. No other contractors received awards under the vehicle. Task orders ranged from small administrative tasks under $100,000 to research studies exceeding $1.7 million; the largest single order was IND-enabling studies valued at $1.9 million (HHSN27100019). All orders carried unrestricted, competitive designations with no small-business set-asides.
Funding came almost exclusively from two NIH components: the National Institute on Drug Abuse placed 33 orders for $9.9 million combined potential (roughly 69% of activity), while NIMH itself funded 8 orders for $4.6 million (roughly 31%). The customer split reflects NIMH's role as contracting office executing work for its sibling institute's portfolio.
Description
The National Institute of Mental Health (NIMH) has awarded a Master IDIQ for providing a full range of in vitro and in vivo preclinical pharmacology and safety (ADMET) studies for the purpose of developing new drugs for nervous system disorders.
IDV awards
| Awardee | IDV award | Awarded |
|---|---|---|
| Southern Research Institute | HHSN271201100005I | |
| Sri International | HHSN271201100004I |
Latest task orders
Show 15 more
Latest 25 of 41 listed here. See the rest on GovTribe.
Top awardees by obligations
| Rank | Awardee | Obligated | Share |
|---|---|---|---|
| 1 | Sri International | $8,788,399 | 61% |
| 2 | Southern Research Institute | $5,694,712 | 39% |
Top funding agencies by obligations
| Rank | Funding agency | Obligated | Share |
|---|---|---|---|
| 1 | Department of Health and Human Services | $14,483,111 | 100% |
Obligations by fiscal year
| Fiscal year | Obligated |
|---|---|
| FY2025 | -$60,426 |
| FY2022 | -$517 |
| FY2021 | -$59,704 |
| FY2020 | -$504,471 |
| FY2019 | -$60,264 |
| FY2018 | -$431,466 |
| FY2017 | -$135,130 |
| FY2016 | $5,018,045 |
| FY2015 | $5,537,576 |
| FY2014 | $522,589 |
| FY2013 | $2,876,813 |
| FY2012 | $1,481,274 |
| FY2011 | $243,759 |
Show all 13
Quick answers
What is the PTNP contract vehicle?
Pharmacology and Toxicology for Neurotherapeutics Program (PTNP) is an indefinite delivery, indefinite quantity (IDIQ) contract vehicle run by National Institutes of Health (Department of Health and Human Services), awarded on September 13, 2011.
Which companies hold PTNP?
2 companies hold PTNP's IDV awards, one each. The latest went to Southern Research Institute on September 13, 2011. The awardees whose task orders obligated the most are Sri International and Southern Research Institute.
How much has been spent through PTNP?
41 task orders have been placed under PTNP, obligating $14,483,111. Their combined current value, with exercised options, is $14,428,077.
What is the shared ceiling of PTNP?
PTNP's shared ceiling is $75,000,000; its task orders have used 19% of it.
Which agencies use PTNP the most?
The departments whose task orders under PTNP obligated the most are Department of Health and Human Services ($14,483,111).
How much was obligated through PTNP in fiscal year 2025?
Task orders under PTNP obligated -$60,426 in fiscal year 2025.
On GovTribe
See this vehicle's full record
- Every IDV award and task order
- Funding by agency, awardee, NAICS and set-aside
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