BARDA Animal Model Development 2011-2016

The Department of Health and Human Services' Office of the Assistant Secretary for Preparedness and Response established this Master IDIQ on May 24, 2011, to develop animal models supporting medical countermeasures for CBRN, influenza, and emerging infectious diseases. Ordering closed on September 27, 2018—nearly eight years ago—and the vehicle is no longer active. A successor vehicle, BARDA Biological Animal Model Development 2017-2022, was awarded in March 2017.

Over its active period, BARDA issued 48 task orders totaling $93.6 million in combined potential value, of which $92 million (98%) has been obligated. Ordering activity peaked early: 16 orders in 2012, then declined to 6–10 annually through 2016. The most recent order was placed in September 2016. All task orders are unrestricted; no set-aside structure applies.

Two firms dominate the prime contractor base. Lovelace Biomedical and Environmental Research Institute holds 10 orders worth $31.8 million combined potential value, while Battelle Memorial Institute holds 15 orders worth $28.2 million. Together they account for roughly 65% of combined potential value and 54% of awarded orders. IIT Research Institute, University of Illinois, and Public Health England round out the top five. All 48 orders were placed by ASPR, the sole customer organization.

Task orders reflect work across radiological and nuclear effects modeling, infectious disease platforms, and medical countermeasure development. Awarded orders include minipig models for hematopoietic and gastrointestinal acute radiation syndrome, nonhuman primate models for melioidosis and MERS-CoV, ferret influenza vaccine models, mousepox models, and production of pathogenic reagents such as Bacillus anthracis spores and Zika virus assays. Pricing is predominantly cost-plus-fixed-fee, with some firm-fixed-price orders. Individual task-order ceilings range from roughly $90,000 to $7.4 million, with most falling in the $1–3 million band. Several tasks included no-cost extensions into 2024 for indirect-rate settlements after completion.

Because this vehicle is closed to new orders and the successor vehicle is now the active procurement channel, pursuing work here is not viable. Existing awardees may be able to exercise final options or closeout modifications, but no new prime awards are available.

The Department of Health and Human Services(HHS) through the Biomedical Advanced Research and Development Authority (BARDA) requires the development of animal models for the development of medical countermeasures for Chemical, Biological, Radiological, Nuclear (CBRN); Influenza; and Emerging Infectious Diseases.