Molecular diversity on demand: engineered polyketide synthases for versatile synthesis for switch program

Other Transaction IDV Awarded Last action

Contract number
HR00112590061
Awardee
Awarding agency
Task orders
0

Award facts

Last date to order
Not on record
IDV ceiling
$7,009,076.00
Contracting staff
NAICS code
Not on record
Set-aside
No set-aside
Competition
Competed Program Solicitation
Pricing
Other

Award details come from SAM.gov/FPDS.

About this IDV

DARPA awarded an Other Transaction IDV to The Regents of the University of California, doing business as University of California, Berkeley, on January 24, 2025, with a ceiling of $7.009 million for research and development of molecular diversity on demand through engineered polyketide synthases for versatile synthesis under the SWITCH program. This OT IDV operates outside the FAR under DARPA's Other Transaction authority and supports fundamental research in synthetic biology and molecular engineering.

UC Berkeley's chemistry and chemical engineering research capabilities align with DARPA's objective to develop engineered polyketide synthases—enzyme systems that enable programmable synthesis of diverse bioactive molecules and natural-product analogs. The award funds incremental R&D effort advancing synthase engineering methodologies that broaden the scope of molecular structures accessible through biological synthesis platforms, a core capability area for the SWITCH program's goals in rapid prototyping of small molecules and complex organic compounds.

No specific period of performance, place of performance, or subsequent task orders are identified in the source material for this OT IDV.

Transactions

Action Obligated Date
Funding Only Action P00004 · Modification to add incremental funding. R & d molecular diversity on demand: engineered polyketide synthases for versatile synthesis $1,273,643
Funding Only Action P00003 $1,064,203
Additional Work (new agreement, FAR part 6 applies) P00002 · Switch phase 1 $1,433,565
Other Administrative Action P00001 · Base - phase 0 $0
Original award $292,987

Quick answers

Who was awarded contract HR00112590061?

HR00112590061 was awarded to The Regents Of The University Of California by Defense Advanced Research Projects Agency (Department of Defense) on January 24, 2025.

How much is contract HR00112590061 worth?

HR00112590061's own ceiling is $7,009,076.

Was contract HR00112590061 competed?

The extent of competition for HR00112590061 was competed.

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