Preclinical prevent cancer program: preclinical efficacy and intermediate endpoint biomarkers; POP: 9/22/15 - 9/21/18

Ended Awarded Last action

Contract number
HHSN261201500036I
Awardee
Awarding agency
Task orders
11 $7,524,334 obligated

Award facts

Opportunity
  • N01CN201500036 Solicitation number
Combined order value
$7,524,334 Current and potential, with all options
Last date to order 100% complete
IDV ceiling 25% used
$29,800,000.00
Maximum order
$29,800,000.00
Award type
Multiple award
Who can order
Only the awarding agency
Set-aside
No set-aside
Competition
Full and Open Competition · 9 offers Negotiated Proposal / Quote
Pricing
Order Dependent (IDV only)

Award details come from SAM.gov/FPDS.

About this IDV

This indefinite delivery contract was awarded by the Department of Health and Human Services' National Institutes of Health National Cancer Institute to the University of Alabama at Birmingham (UAB) to support the agency's Preclinical Prevent Cancer Program. The program focuses on evaluating the preclinical efficacy and identifying intermediate biomarkers for potential cancer prevention agents prior to clinical trials.

Under this $29.8 million multiple-award IDC, UAB has been issued multiple firm-fixed-price delivery orders ranging from $432,272 to $1.27 million. The work involves preclinical research and development in areas such as the development of multi-antigen vaccines for bladder cancer prevention, evaluation of chemopreventive agents like 4-methylumbelliferone and STAT3 antagonists, and testing combinations of "clinically-ready" drugs like everolimus, naproxen, bazedoxifene, and lapatinib for breast and bladder cancer prevention. The contracted research is being conducted at UAB's facilities in Birmingham, Alabama, and UAB has issued subcontracts to partners like the University of Washington to support the work. This IDC does not have any set-aside designations.

Task orders

Task order Ordering agency Obligated Awarded
Preclinical development of a chemopreventive agent, 4-methylumbelliferone(4-MU) HHSN2512015000361 torfp: 2018-E07 PP… 75N91018F00010 National Cancer Institute (NIH) $1,271,041
Further development of multi-antigen vaccines for primary and secondary prevention of bladder cancer… 75N91018F00011 National Cancer Institute (NIH) $901,729
Prevention of urinary bladder cancer with two "clinically-ready agents (everolimus and naproxen) when administered in… 75N91018F00008 National Cancer Institute (NIH) $432,272
Evaluating whether a concurrent retinoid x receptor agonist can enhance the efficacy of the HER2-IGFPB2-igflr vaccine… 75N91018F00009 National Cancer Institute (NIH) $930,464
Evaluation of STAT3 antagonists in the prevention of mammary cancer HHSN26100007 National Cancer Institute (NIH) $492,314
Multi-antigen vaccines for the primary and secondary prevention of bladder cancerto POP: 9/15/2017 - 3/14/2019 HHSN26100006 National Cancer Institute (NIH) $636,313
Evaluation of 'clinical-ready' agents (bazedoxifene and lapatinib) in combination for the prevention of ER+ and ER… HHSN26100005 National Cancer Institute (NIH) $681,826
R & d- medical: biomedical (basic research) HHSN26100004 National Cancer Institute (NIH) $922,642
Evaluation of the cancer prevention efficacy of GLG-302 HHSN26100003 National Cancer Institute (NIH) $574,237
Evaluation of agents/protocols that inhibit two major pathways involved in human urinary bladder cancer(PI3K, egfr) and… HHSN26100002 National Cancer Institute (NIH) $679,103
Preclinical prevent cancer program: preclinical efficacy and intermediate endpoint biomarkers.task order: contract… HHSN26100001 National Cancer Institute (NIH) $2,394
Show all 11

Transactions

Action Obligated Date
Other Administrative Action P00003 $0
Additional Work (new agreement, FAR part 6 applies) 2 · Efficacy idiqs- increase programmatic maximum $0
Other Administrative Action 1 $0
Original award $0

Quick answers

Who was awarded contract HHSN261201500036I?

HHSN261201500036I was awarded to University Of Alabama At Birmingham by National Cancer Institute (National Institutes of Health) on September 22, 2015.

How much is contract HHSN261201500036I worth?

Orders under HHSN261201500036I have obligated $7,524,334. HHSN261201500036I's own ceiling is $29,800,000. A single order can be worth up to $29,800,000.

How many orders have been placed under contract HHSN261201500036I?

11 orders have been placed under HHSN261201500036I, the latest on September 17, 2018.

Who can order from contract HHSN261201500036I?

HHSN261201500036I is a multiple award indefinite delivery contract. Only the awarding agency can place orders on it.

Is contract HHSN261201500036I part of a contract vehicle?

Yes. HHSN261201500036I is part of PREVENT Cancer Program (PREVENT).

Was contract HHSN261201500036I competed?

The extent of competition for HHSN261201500036I was full and open competition. The government received 9 offers.

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