The Environmental Protection Agency (EPA) awarded a $13 million single-award Indefinite Delivery Indefinite Quantity (IDIQ) contract to Cyprotex US LLC, a foreign-owned for-profit contract research organization, to provide high-throughput toxicokinetics (HTTK) services. This IDIQ contract, awarded in May 2020, supports the EPA's HTTK program, which uses in vitro assays to rapidly and cost-effectively generate toxicokinetic data on hundreds of industrial chemicals and environmental contaminants. This data helps EPA scientists better understand the absorption, distribution, metabolism, and excretion of these compounds, enabling more informed assessments of their potential human health and environmental impacts. The contract has a five-year period of performance and does not have a set-aside designation. Under this IDIQ, Cyprotex has received multiple firm-fixed-price delivery orders totaling over $3.5 million to date for toxicokinetic testing services performed at its facilities in Watertown and Framingham, Massachusetts. The initial solicitation for this IDIQ contract was issued by the Department of the Interior on behalf of the EPA in November 2019, seeking a contractor to provide HTTK services to support the agency's chemical risk assessment efforts. The contract was awarded as a single-award IDIQ with a 60-month period of performance, utilizing firm-fixed-price delivery orders. This contractual approach allows the EPA to efficiently and flexibly obtain specialized toxicokinetic testing services from Cyprotex as needed to advance its mission of protecting human health and the environment.
Mod # | Description | Reason For Modification | Federal Obligation (Click to sort descending) | Date (Click to sort ascending) |
|---|---|---|---|---|
| P00009 | Other Administrative Action | $0 | 12/17/24 | |
| P00008 | Other Administrative Action | $0 | 11/14/24 | |
| P00007 | Supplemental Agreement for work within scope | $0 | 9/20/24 | |
| P00006 | Other Administrative Action | $0 | 11/28/23 | |
| P00005 | Other Administrative Action | $0 | 7/26/23 |
Name | Description | Awardee | Potential Value (Click to sort descending) | Award Date (Click to sort descending) | Completion Date (Click to sort descending) | Updated At (Click to sort descending) |
|---|---|---|---|---|---|---|
Delivery Order 140D0420D0003-140D0422F0336 | Cyprotex US LLC | $133.7k | 4/20/22 | 4/24/23 | 4/20/22 | |
Delivery Order 140D0420D0003-140D0425F0082 | Cyprotex US LLC | $451.8k | 12/23/24 | 12/29/25 | 3/13/25 | |
Delivery Order 140D0420D0003-140D0424F0076 | Cyprotex US LLC | $362.2k | 12/1/23 | 1/30/25 | 6/10/25 | |
Delivery Order 140D0420D0003-140D0420F0266 | Cyprotex US LLC | $1.8m | 5/6/20 | 5/5/21 | 6/20/23 | |
Delivery Order 140D0420D0003-140D0422F0137 | Cyprotex US LLC | $65.0k | 1/10/22 | 1/9/23 | 1/6/22 |
Name | Description | Solicitation Number | Federal Agency | Type | Posted Date (Click to sort descending) |
|---|---|---|---|---|---|
High-Throughput Toxicokinetics (HTTK) | 140D0420R0008 | Department of the Interior Departmental Offices Interior Business Center | Solicitation 3/4 | 12/23/19, 12:59 PM | |
High Throughput Toxicokinetics (HTTK) | 140D0420R0008 | Department of the Interior Departmental Offices Interior Business Center | Pre-Solicitation 1/4 | 11/26/19, 2:08 PM | |
High-Throughput Toxicokinetics (HTTK) | 140D0420R0008 | Department of the Interior Departmental Offices Interior Business Center | Award Notice 4/4 | 5/1/20, 12:03 PM | |
High Throughput Toxicokinetics (HTTK) | 140D0420R0008 | Department of the Interior Departmental Offices Interior Business Center | Special Notice 2/4 | 11/26/19, 2:16 PM |