Establishing industrial production of components that enable expanding accessibility of pet imaging to cancer patient population. - CRP technical assistance is intended to accomplish the following for…

Establishing industrial production of components that enable expanding accessibility of pet imaging to cancer patient population. - CRP technical assistance is intended to accomplish the following for tracer-QC product under development. IT will establish industrial production methods (specifically high-precision injection molding) necessary to ensure consistent and controlled scale-up manufacturing of tracer-QC analysis plates that are currently manufactured by non-salable, variable and costly machining process. CRP problem. Trace-ability is focusing a lot of current effort on scaling up tracer-QC kit production to the levels that can supply the entire pet industry with high-quality kits. However, there is one aspect where the current manufacturing technology is not scalable and carries quality risks. IT needs to be replaced by a completely new technology in order to support the pet industry. Specifically, IT is the manufacturing of the core tracer-QC analysis plate in which all QC assessments take place. Current plates are made by cutting standard 384-well plates. Such process is not scalable. IT has inherent plate-to-plate variability and a high risk of debris contaminating the wells required for precise optical analysis. CRP solution. Trace-ability has developed a proposal together with agilent technologies, INC. To manufacture analysis plates by injection molding. This project is designed to establish scalable production of analysis plates and RE- validate all existing tracer-QC assays in these plates. Specific aim 1: scalable injection molding process for manufacturing high-quality analysis plates. The "high-quality" acceptance criteria are (a) well absorbance