Project Grant S15OD042567
- The Department of Health and Human Services National Institutes of Health Office of the Director awarded Seattle Children's Research Institute (doing business as Seattle Children's Hospital) $516,175 under the Research Infrastructure Programs (CFDA 93.351) on August 1, 2026, to develop transgenic technology in Acomys (spiny mice), a non-traditional mammalian model with naturally evolved adult non-fibrotic regenerative capacity. The recipient will establish whole-animal transgenesis pipelines...
- Thomas Jefferson University's Laboratory Animal Services (LAS) Department received $347,945 in Project Grant funding from the National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) to modernize animal research infrastructure. The award, effective August 1, 2025 through July 30, 2026, supports the acquisition and installation of an OptiMice 100-cage individual ventilated caging (IVC) system for the university's oldest animal research...
- The National Institutes of Health Office of the Director awarded Cornell University $349,982 under the Research Infrastructure Programs (CFDA 93.351) on September 1, 2026 to advance germ-free and gnotobiotic mouse husbandry operations at the Cornell Center for Animal Resources and Education. The award funds the acquisition of isolator caging systems and biosafety changing systems designed to maintain sterile germ-free environments for research mice. The isolator systems feature enhanced ports...
- The National Institutes of Health Office of the Director awarded Biometric Positioning Systems LLC $1,004,323 on September 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to develop a portable device that mechanically guides needle insertion into the tail veins of laboratory mice and rats. The device addresses the high failure rate and occupational hazards of manual freehand tail-vein injection in preclinical research. Current commercial devices require operators to achieve...
- The National Heart, Lung, and Blood Institute awarded Seattle Children's Hospital, doing business as Seattle Children's Research Institute, $1,839,440 on August 5, 2026, under the Cardiovascular Diseases Research program (CFDA 93.837) to investigate how heavy chain hyaluronan and TSG-6 modulate lung inflammation during respiratory syncytial virus (RSV) infection. The research examines the extracellular matrix's role in RSV pathogenesis, focusing on age-dependent inflammation in young children....
- The National Institute of General Medical Sciences awarded Seattle Children's Research Institute $2.096 million on May 1, 2026, under the Biomedical Research and Research Training program (CFDA 93.859) to develop an AI-driven platform for generating conditionally stable nanobodies for intracellular detection and protein manipulation applications. The project spans four years through April 30, 2030, and will deliver three core outputs. First, an expanded AI-based nanobody stability prediction...
- Federal Grant Award Summary Seattle Children's Research Institute received a $516,175 Project Grant awarded on August 1, 2025, by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853). The two-year research initiative, scheduled for completion by July 31, 2027, focuses on investigating cerebellar development in ferrets to advance understanding of human cerebellar development...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Seattle Children's Hospital, doing business as Seattle Children's Research Institute, $724,950 on May 15, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award funds research to understand the mechanism of H3K9me3 heterochromatin-based silencing and selectively disrupt heterochromatin to improve the reprogramming of human fibroblasts into induced hepatocytes...
- The National Institutes of Health Office of the Director awarded The Trustees of Columbia University in the City of New York $350,000 on September 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to modernize sterilization infrastructure at the Irving Cancer Research Center vivarium. Columbia will replace a bulk steam autoclave with a Gruenberg Steri-Dry bulk dry-heat sterilizer to sterilize cages supporting barrier housing for patient-derived xenografts, immunocompromised and...
- The National Institute of Neurological Disorders and Stroke awarded a Cooperative Agreement totaling $6.865 million to Seattle Children's Hospital (doing business as Seattle Children's Research Institute) on September 19, 2025, under the Drug Use and Addiction Research Programs (CFDA 93.279), with ultimate completion on July 31, 2030. The award funds development of a precision health model for pediatric chronic primary pain using the PEDSnet national pediatric learning health system...
The National Institutes of Health Office of the Director awarded $350,000 to Seattle Children's Hospital (doing business as Seattle Children's Research Institute) on September 1, 2026, under the Research Infrastructure Programs (CFDA 93.351) to purchase a digital ventilated cage system from Tecniplast for the Behavioral Phenotyping Core vivarium. The DVC system incorporates continuous, real-time monitoring of animal activity and environmental cage parameters including temperature, humidity, water levels, and food levels, with automated notifications to personnel when critical thresholds are reached. The system enables non-invasive collection of behavioral data from rodent models, reduces animal husbandry overhead costs through on-demand rather than batch cage changes, and decreases animal stress by minimizing handling frequency. The technology maintains the same physical footprint as traditional cage rack systems while enhancing rigor and reproducibility of behavioral phenotyping data collected within the core facility. The award funds equipment acquisition and runs through August 31, 2027. Place of performance is Seattle, WA 98101. This project grant supports the institute's newly built, 3,000-square-foot behavioral phenotyping facility dedicated to collecting reproducible and accurate behavioral data from animal models for translational biomedical research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $350.0k | 8/24/26 |