Project Grant S10OD034267
- This National Science Foundation (NSF) Geosciences grant (CFDA 47.050) will provide $490,000 to the Carnegie Institution For Science to acquire an advanced X-ray detector, the EIGER2 S CdTe 9M, for the Advanced Photon Source at Argonne National Laboratory. The new detector will enhance the institution's capabilities to conduct in-situ, high-pressure and high-temperature studies of the structure and composition of Earth and planetary materials, including minerals, melts, and iron alloys. This...
- This federal Project Grant award from the Department of Health and Human Services National Institutes of Health Office of the Director under the Research Infrastructure Programs (CFDA 93.351) provides $1,964,800.00 to The Research Foundation For The State University Of New York, doing business as Stony Brook University, to upgrade the X-ray area detector of the Frontier Microfocusing Macromolecular Crystallography (FMX) beamline at the National Synchrotron Light Source-II. The new Eiger2 XE 9M...
- Sydor Instruments, LLC was awarded a $1,350,000 Project Grant from the Department of Energy Office of Science on February 22, 2021 to develop an ASIC-coupled microchannel plate for time resolved, single-photon soft x-ray detection. The grant is being used to deliver a scientific instrument that will enable new discoveries by allowing researchers to detect individual photons in the soft x-ray range of the electromagnetic spectrum with high temporal resolution. This work directly supports the...
- This Project Grant award from the National Science Foundation's (NSF) Engineering Directorate (CFDA 47.041) provides $399,000 to The Research Foundation for the State University of New York (SUNY) to develop a new generation of cost-effective, scalable, and stable radiation detectors with ultra-high detectivity. This is a joint effort between the University at Buffalo, University of Cambridge, and University of Oxford to address the challenge of engineering materials and manufacturing...
- This Project Grant award from the National Science Foundation's Biological Sciences (CFDA 47.074) program provides $743,852 to Saint Louis University (SLU) to acquire an XTALAB SYNERGY-R single crystal diffractometer. This state-of-the-art scientific instrument will enable researchers across 13 different SLU colleges, as well as collaborators from Southern Illinois University Edwardsville, to collect high-quality X-ray diffraction data from organic compounds and biological macromolecules. The...
- The University of Pittsburgh received a $308,651 Project Grant from the National Science Foundation to acquire a single crystal x-ray diffractometer for research and education. Funded under the NSF's Mathematical and Physical Sciences program (CFDA 47.049), the award will support the research of Professor Raul Hernandez Sanchez and Nathaniel Rosi through the acquisition of a dual-source diffractometer equipped with copper and molybdenum x-ray sources, an enhanced detector, and cryogenic...
- This $535,686 National Science Foundation project grant will fund the acquisition of a comprehensive X-ray scattering system for in situ studies at the University of California, Davis through August 2025. The system will transform research, education, and outreach in materials characterization across California's Central Valley under the Mathematical and Physical Sciences program (CFDA 47.049). Specifically, the state-of-the-art instrument serves as a flagship tool for advanced materials...
- This Project Grant award from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) provides $1,999,997 to Arizona State University (ASU) to acquire an electron energy filtering system and direct electron detector camera to upgrade the university's cryo-electron microscopy (cryo-EM) capabilities. The new instrumentation aims to improve the resolution and data quality of cryo-EM studies, enabling ASU researchers to better investigate biomolecular...
- The Department of Energy Office of Science awarded Brimrose Technology Corporation a $1,349,577 project grant under the Office of Science Financial Assistance Program (CFDA 81.049) to develop cadmium magnesium telluride for picosecond response x-ray optical laser photodetectors. The Office of Science's mission is to deliver scientific discoveries and major scientific tools to transform our understanding of nature and advance U.S. energy, economic, and national security. Under this award...
- The National Science Foundation (NSF) Office of Integrative Activities awarded Susquehanna University a $200,170 Project Grant under the Integrative Activities program (CFDA 47.083) to acquire a single-crystal X-ray diffractometer. This instrument will support primarily undergraduate research in the greater Susquehanna Valley region, including efforts at Susquehanna University, Bucknell University, Lycoming College, Elizabethtown College, and Wilkes University. The diffractometer, which has a...
HIGH-SPEED HIGH-SENSITIVITY DETECTOR FOR X-RAY MICRO-CRYSTALLOGRAPHY AT GM/CA@APS - PROJECT SUMMARY GM/CA @ APS OPERATES TWO HIGHLY SUCCESSFUL UNDULATOR BEAMLINES AS A NATIONAL USER FACILITY FOR MACROMOLECULAR CRYSTALLOGRAPHY AT THE ADVANCED PHOTON SOURCE (APS). THE GM/CA GROUP DEVELOPS AND OPERATES WORLD-LEADING BEAMLINES IN MICRO-CRYSTALLOGRAPHY, OFFERING USER-SELECTABLE "MIN-BEAM" SIZES DOWN TO 5 M FOR ALL SAMPLES. GIVING USERS THE ABILITY TO CHANGE BEAM SIZE RAPIDLY, RELIABLY, AND ON-DEMAND WITHOUT STAFF INVOLVEMENT TO OPTIMIZE THE BEAM SIZE FOR A GIVEN PROJECT HAS LED TO A SWEEPING CHANGE IN EXPERIMENTAL PRACTICE. THE HARDWARE FOR MICRO-CRYSTALLOGRAPHY IS COUPLED WITH SOPHISTICATED SOFTWARE TOOLS IN THE JBLUICE USER INTERFACE. ESSENTIAL TOOLS INCLUDE RASTERING TO FIND MICRO- CRYSTALS IN COMPLEX MOUNTS OR TO IDENTIFY THE BEST DIFFRACTING REGIONS OF LARGER INHOMOGENEOUS SAMPLES, HELICAL DATA COLLECTION TO DISTRIBUTE DOSE ALONG ROD-SHAPED CRYSTALS AND SERIAL DATA COLLECTION FROM VISCOUS JETS OR FIXED TARGETS. CONSEQUENTLY, THE GM/CA BEAMLINES ARE OVERSUBSCRIBED DUE TO THE HIGH DEMAND BY A GROWING NUMBER OF INVESTIGATORS WITH CHALLENGING NIH-FUNDED STRUCTURAL PROJECTS. WE ARE ABOUT TO EMBARK ON AN EXCITING NEW PHASE. OUR VISION IS TO PROVIDE THE HIGHEST RESOLUTION DATA ACHIEVABLE FROM CHALLENGING PROBLEMS IN STRUCTURAL BIOLOGY THAT TEND TO YIELD TINY, WEAKLY DIFFRACTING CRYSTALS. THE APS WILL SHUT DOWN IN APRIL OF 2023. THE STORAGE RING WILL BE UPGRADED (APS-U) WITH A 4TH GENERATION MULTI-BEND ACHROMAT STORAGE RING, INCREASING THE X-RAY BRIGHTNESS BY TWO TO THREE ORDERS OF MAGNITUDE DEPENDING ON THE X-RAY ENERGY. IN PREPARATION FOR THE APS-U START-UP IN APRIL 2024, NEW FOCUSING OPTICS WERE INSTALLED ON 23ID-D. THE NEW MIRRORS WILL FOCUS THE APS-U SOURCE TO A BEAM AS SMALL AS ~5-MICRONS, AND NEW COMPOUND REFRACTIVE LENSES WILL PROVIDE AN INTENSE ~1-MICRON BEAM. COMBINING THE APS-U SOURCE AND THE NEW OPTICS IS A GAME-CHANGING OPPORTUNITY FOR STRUCTURAL BIOLOGY. HOWEVER, BEAMLINE 23ID-D HAS A PILATUS3 6M DETECTOR THAT WILL BE TEN YEARS OLD WHEN THE APS-U STARTS UP AND MUST BE REPLACED. TO REALIZE OUR VISION, WE PROPOSE TO PURCHASE AN EIGER2 XE 16M CDTE DETECTOR FROM DECTRIS, AG, A NEXT-GENERATION HIGH-SPEED, HIGH COUNT RATE DETECTOR WITH HIGH QUANTUM EFFICIENCY FOR THE DETECTION OF X-RAYS WITH ENERGIES FROM 6 - 35 KEV.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | ($93) | 6/30/25 | ||
| Not listed | $2.0m | 4/17/23 |