Project Grant RF1NS143760
- The National Institute on Aging (NIA) has awarded a $640,906 project grant under CFDA 93.866 Aging Research to the University of Wisconsin-Madison to conduct research on "Elucidating Cerebrovascular Disease Pathways to Cognitive Decline with Vascular Neuroimaging." The 5-year project aims to utilize advanced neuroimaging techniques to understand the vascular contributions to cognitive impairment and dementia (VCID), and assess their relationship to Alzheimer's disease proteinopathy....
- The National Institute on Aging (NIA) awarded a $2,244,471 Project Grant under CFDA 93.866 (Aging Research) to Oregon Health & Science University (OHSU) to develop a first-in-class, CNS-penetrant small molecule agonist for G protein-coupled receptor 39 (GPR39) as a potential treatment for vascular cognitive impairment and dementia (VCID). The 3-year project from September 2023 to August 2026 will use in vitro and in vivo assays to identify lead compounds, determine their safety and...
- This Project Grant award of $2,549,080.00, provided by the National Institute on Aging (NIA) under the Aging Research program (CFDA 93.866), supports research to investigate the impact of SARS-CoV-2 infection on the cerebrovasculature as a risk factor for vascular contributions to cognitive impairment and dementia (VCID). The award, with a performance period from August 11, 2025 to July 31, 2029, will fund the University of Illinois to: Determine how prior SARS-CoV-2 infection influences...
- This federal Project Grant award, issued by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, provides $4,693,249 to the University of California, Los Angeles (UCLA) to conduct research on defining the molecular spectrum of white matter vascular lesions that drive vascular cognitive impairment and dementia (VCID). The project aims to develop a better understanding of...
- This federal Project Grant award, valued at $1,552,000.00 and provided by the National Institute on Aging (CFDA 93.866 - Aging Research), supports a research study examining the relationship between markers of vascular and immune dysfunction, such as platelet aggregation and neutrophil levels, and their association with dementia risk and increased Alzheimer's disease (AD) biomarkers. The study, conducted by New York University School of Medicine, aims to integrate biofluid biomarker data with...
- This $5,789,766 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) will examine the effects of intensive blood pressure control on mild cognitive impairment, dementia, and plasma biomarker trajectories by Alzheimer's disease pathology. The study aims to elucidate neuroprotective effects in the racially and ethnically diverse SPRINT trial cohort. The University of Utah is the primary awardee and will conduct this research over a period of approximately 5...
- This federal Project Grant award of $633,146 from the National Institute of Neurological Disorders and Stroke (NINDS), under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program, supports research to determine modifiable factors that impact post-stroke vascular cognitive impairment and dementia (VCID). The primary objectives are to: 1) quantify the association between performance of cognitively stimulating activities after stroke and...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) provides $136,778 to Wake Forest University Health Sciences to conduct research on the impact of cerebral small vessel disease on brain networks and cognitive impairment. The 5-year project aims to: 1) Utilize advanced brain network modeling to understand the resilience and disruption caused by cerebral microbleeds, 2) Develop an integrative machine learning model to improve prediction of...
- This federal Project Grant award of $428,410 was provided by the National Institute on Aging (NIA) under the Aging Research Federal Grant Program (CFDA 93.866). The grant is funding the Research and Education in Alzheimer's Disease and Dementias Initiative for Equity (READDIE) program at the Wake Forest University School of Medicine (WFUSM). The READDIE program is designed to facilitate postbaccalaureate trainees' entry into and completion of PhD programs in Alzheimer's disease and related...
- This federal Project Grant award from the National Institute on Aging (CFDA 93.866 Aging Research) is for the research project "Impact of Hypertension and Aging on Postoperative Delirium". The $715,801 grant, awarded on June 1, 2025, supports Duke University's research to elucidate the contributions of endothelial cells and perivascular macrophages to surgery-induced neuroinflammation, blood-brain barrier disruption, and delirium-like behavior in aging and hypertension. The overarching...
This federal Project Grant award of $2,421,629 from the National Institute on Aging (CFDA 93.866 - Aging Research) supports the "Inspiring Healthy Engagement and Learning for Vascular Dementia (I-HEAL)" project. The grant aims to address gaps in clinical trial participation for vascular contributions to cognitive impairment and dementia (VCID), with a focus on populations residing in the Stroke Belt region of the southeastern United States. Key objectives include examining factors influencing clinical trial readiness and developing tailored strategies to improve VCID clinical trial participation. The grant was awarded to Wake Forest University Health Sciences, a leading academic medical center, and will be conducted from Sep 1, 2025 through Aug 31, 2029.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $2.4m | 9/3/25 |