Project Grant R61NS143667
- The National Institute of Neurological Disorders and Stroke awarded a cooperative agreement to Case Western Reserve University for $1,202,540 on September 1, 2026, to conduct an exploratory trial of the RESTORES (Revolutionary Electrical Stimulation Technology to Optimize Recovery of Everyone with Spinal Cord Injury) system. The recipient will customize and program open-source Networked Neuroprosthesis (NNP) components—a modular peripheral neurostimulation device designed to address multiple...
- The National Institute of Neurological Disorders and Stroke awarded Drexel University $149,190 on July 14, 2026, under CFDA 93.853 (Extramural Research Programs in the Neurosciences and Neurological Disorders) to conduct research on transcutaneous spinal cord stimulation and its mechanisms for reducing spasticity following spinal cord injury. The research investigates whether transcutaneous spinal cord stimulation improves spasticity after spinal cord injury by upregulating KCC2, a chloride...
- The National Institute of Neurological Disorders and Stroke, part of the Department of Health and Human Services National Institutes of Health, awarded $642,712 to The University of Texas Southwestern Medical Center on June 15, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate adult neurogenesis as a strategy for improving urinary function after contusion spinal cord injury. The project systematically examines...
- The National Institute of Neurological Disorders and Stroke awarded Mayo Clinic $622,784 on July 21, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate acute and chronic repercussions of spinal cord stimulation following spinal cord injury. The research quantifies blood pressure instability after spinal cord injury, which interrupts descending autonomic regulatory signals and causes loss of consciousness, stroke,...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded Rancho Research Institute $727,810 on June 1, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to investigate functional and structural brain connectivity alterations in post-stroke lower urinary tract dysfunction and to identify biomarkers predicting response to transcutaneous spinal cord stimulation therapy. The research combines three integrated aims. Aim 1 uses...
- The National Institute of Neurological Disorders and Stroke awarded The Ohio State University $791,792 on September 1, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to develop and adapt a wearable electromyography-triggered functional electronic stimulation (EMG-FES) system for stroke rehabilitation. The funded work focuses on engineering the NeuroLife Sleeve, a research-grade prototype sleeve embedded with 150 dual...
- The National Institute of Neurological Disorders and Stroke awarded Emory University $234,750 on January 26, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to investigate neuromodulation of somato-sympathetic postganglionic activity after spinal cord injury. The research develops animal models incorporating clinically analogous epidural spinal cord stimulation to understand how neuromodulation can restore autonomic function...
- The University of Texas Health Science Center at Houston received a $1,067,612 Project Grant from the Defense Health Agency under the Military Medical Research and Development program (CFDA 12.420) for a three-year hybrid implementation-effectiveness trial examining home neuromodulation as a treatment approach for neurogenic bladder management in individuals with spinal cord injury. The award, effective October 1, 2025, through September 30, 2028, supports research and development services...
- The National Institute of Diabetes and Digestive and Kidney Diseases awarded the University of Houston System $167,696 on August 27, 2026, under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847) to develop intelligent bioelectronic implants for diagnosis and neuromodulation of neurogenic bladder dysfunction. The award funds research to address urological dysfunction following spinal cord injury, particularly neurogenic bladder and detrusor sphincter...
- This federal Project Grant award for $773,399.00, funded by the Department of the Army Medical Command under the Military Medical Research and Development program (CFDA 12.420), supports research at Case Western Reserve University to investigate neuromodulation for improving bladder function in a large animal model of spinal cord injury (SCI). The award, which runs from September 30, 2024 to September 29, 2027, will enable the university's researchers to explore innovative approaches to...
The National Institute of Neurological Disorders and Stroke awarded The Cleveland VA Medical Research & Education Foundation $572,132 on August 22, 2026, under the Extramural Research Programs in the Neurosciences and Neurological Disorders program (CFDA 93.853) to design and test a prototype noninvasive electrical stimulation device and determine its effect on bladder control for women with spinal cord injury–related neurogenic bladder dysfunction. The project targets bladder hyperreflexia, a condition in which the bladder reflexively contracts at small volumes, causing incontinence, urinary tract infections, renal damage, and reduced quality of life in individuals with spinal cord injury. The recipient is developing a surface genital nerve stimulation (GNS) device that uses electrical stimulation to inhibit reflexive bladder contractions. Prior research demonstrated that surface GNS reduces incontinence during one month of home use, but participant feedback identified design limitations including poor electrode interface, wired connections, and device size. This award funds prototype refinement and a one-month home-use study to validate the improved device's effect on bladder control in women with spinal cord injury. Successful completion is intended to support a multi-site study and eventual clinical implementation. Work is performed in Cleveland, Ohio. The period of performance runs through July 31, 2028. The award is classified as a Project Grant, assistance type supporting extramural research in neuroscience and neurological disorders.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $572.1k | 8/21/26 |