The National Institute of Mental Health (NIMH) awarded Openmindxr LLC a $449,729 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to develop a suite of immersive virtual reality (VR) programs aimed at improving social skills in children with ADHD. The 2-year grant, effective June 1, 2025, will fund the conversion of research software into a combined VR program that can be used at home on a VR headset. The program will consist of three modules: PerspectiveR to help...
This federal Project Grant award of $389,735.00 was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The project aims to identify the neural correlates of mental simulation in multi-step planning, which is essential for decision-making and is often impaired in psychiatric and neurological disorders. The research team at New York University will use a combination of fMRI, MEG neuroimaging, and eye-tracking to study the...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), is funding a $211,248 research project to elucidate the neural mechanisms governing fear and anxiety responses within the human hippocampal-amygdala circuit. The project aims to 1) investigate the acquisition, extinction, and renewal of fear responses, 2) explore whether targeted stimulation of the amygdala can facilitate recovery from maladaptive fear...
This federal Project Grant award of $592,831, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports research to understand the neural circuit mechanisms linking early life trauma to impulsive aggression. The primary goal is to characterize the role of the thalamic nucleus reuniens (RE) and its projections to the ventral hippocampus in mediating the maladaptive effects of early life trauma on aggressive behaviors. The...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) is funding a $423,500 research project conducted by the University of Rochester. The project aims to derive electroencephalogram (EEG) responses from the early stages of the human visual cortex to study predictive processing in schizophrenia. Specifically, the researchers will use innovative visual stimuli and experiments to measure "perceptual...
The National Institute of Mental Health (NIMH) awarded a $845,163 Project Grant under the Mental Health Research Grants (CFDA 93.242) program to The Feinstein Institutes for Medical Research. The project aims to develop a low-cost, low-burden approach that produces accurate, objective markers of psychosis severity using automated speech and language analysis. This would serve as "vital signs" for monitoring psychosis in a longitudinal clinical context. The project will first build a...
The federal Project Grant award R01MH139352, totaling $429,323.00, was provided by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants (CFDA 93.242) program. The grant supports research to investigate cognitive flexibility and the neural mechanisms underlying cognitive thalamocortical dynamics, with the goal of advancing understanding and treatment of mental illnesses characterized by cognitive inflexibility, such as schizophrenia. The primary awardee is New...
This federal Project Grant award of $1,920,113, awarded by the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242), supports a research project titled "Narrowing the Mechanistic Gap for Anterior Prefrontal Cortex Function". The project aims to conduct a deep dive on the anatomy and function of the anterior lateral prefrontal cortex (ALPFC) region of the brain, which has been implicated in various mental health disorders such as...
This Project Grant award from the National Institute of Mental Health (NIMH), under the Mental Health Research Grants program (CFDA 93.242), provides $811,404 to The Trustees of Columbia University in the City of New York to conduct research on the neural circuitry underlying anticipatory anhedonia in schizophrenia. The research aims to utilize a computational psychiatry approach to dissect the neural mechanisms of altered reward anticipation, which may serve as novel targets for treating...
This Project Grant award from the National Institute of Mental Health (NIMH) under the Mental Health Research Grants program (CFDA 93.242) provides $128,000 to the Boston VA Research Institute, Inc. to investigate the neural mechanisms underlying abnormal spontaneous gamma activity (SGA) in schizophrenia and translational mouse models. The research aims to determine if increased SGA in schizophrenia and in mouse models induced by ketamine administration or optogenetic stimulation of...