The University of Illinois was awarded a $449,726 Project Grant from the National Cancer Institute (CFDA 93.396 Cancer Biology Research) to develop innovative tools that enable rapid and sensitive detection of dynamic changes in protein interactions within cancer cells. Specifically, the university is creating three orthogonal methods using specialized biotin labeling enzymes and biotin analogs to monitor protein interaction networks in living cells with high temporal resolution of one minute or less. This enhanced ability to map transient protein complexes will significantly improve researchers' understanding of the signaling processes driving tumor formation and progression, potentially leading to new cancer treatment approaches. The award commenced on January 2, 2025 and is scheduled for completion by December 31, 2027.
Generated 3/4/25, 7:17 AM