Project Grant R61AI187114
Award Date
4/7/25
Completion Date
3/31/28
Dollars Obligated
$406K
Federal Agency
National Institute of Allergy and Infectious Diseases
Federal Grant Program
93.855
Assistance Type
Project Grant
Place of Performance
Massachusetts, USA
Similar Awards
This $392,710 federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) aims to establish continuous, high-yield culture systems for the malaria parasite Plasmodium vivax (P. vivax). The research objectives are to (1) develop P. vivax strains that can robustly invade reticulocytes in culture, and (2) improve P. vivax development in vitro by mimicking the bone marrow microenvironment....
The National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), awarded a $267,168 Project Grant (R61AI187100) to the Institut Pasteur DU Cambodge, a foreign-owned non-profit research organization in Phnom Penh, Cambodia. The grant funding, awarded on December 27, 2024, with a completion date of November 30, 2027, supports research aimed at establishing robust and long-term in vitro cultures of Plasmodium vivax (P....
The National Institute of Allergy and Infectious Diseases (NIAID) awarded a $889,749 Project Grant (CFDA 93.855 - Allergy and Infectious Diseases Research) to Harvard College President & Fellows Of (Harvard T.H. Chan School of Public Health) to conduct research on identifying the Plasmodium falciparum invasion ligand bindome - the set of parasite proteins that bind to and facilitate the invasion of human red blood cells during malaria infection. The key objectives of this 2-year project...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $430,350.00 to the University of Georgia Research Foundation, Inc. to conduct comparative transcriptomics research on Plasmodium vivax strains in order to understand the molecular mechanisms governing hypnozoite formation. The project aims to determine if Plasmodium vivax sporozoites are pre-programmed to...
This Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), provides $147,656 to support research aimed at understanding the role of transmembrane proteins in the cell division process of the malaria parasite Plasmodium falciparum. The research will utilize biochemical and microscopy approaches to investigate how these transmembrane proteins contribute to the basal complex, which drives...
This federal Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to characterize a novel cytoskeletal protein, PFFIG, in the malaria parasite Plasmodium falciparum. The $207,170 grant, awarded on May 29, 2024, will enable the primary awardee, President and Fellows of Harvard College/Harvard Medical School, to use inducible knockout systems and advanced microscopy...
This $153,512 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855) supports research to understand and overcome immune evasion mechanisms used by Plasmodium parasites, the causative agents of malaria. The research aims to characterize the memory B cell response to the circumsporozoite protein (CSP) antigen, which is the target of currently deployed malaria vaccines, in order to identify...
This $1,845,103 Project Grant award, funded by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), supports research to identify surface-exposed proteins on early mosquito-stage Plasmodium falciparum parasites. The goal is to accelerate the discovery of transmission-blocking vaccine candidates that can prevent malaria transmission from humans to mosquitoes. The key activities include using mass...
This $1,121,728 Project Grant award from the National Institute of Allergy and Infectious Diseases (NIAID), under the Allergy and Infectious Diseases Research program (CFDA 93.855), will support research at Drexel University to investigate the fundamental biology of the ring stage of Plasmodium falciparum, the most lethal malaria parasite. The researchers will focus on understanding the proton pump mechanism that enables the metabolically inactive ring stage parasites to survive within red blood...
This Project Grant award, valued at $862,400 and made by the National Institute of Allergy and Infectious Diseases (NIAID) under the Allergy and Infectious Diseases Research program (CFDA 93.855), aims to elucidate an essential mechanism for iron uptake by the Plasmodium parasite's apicoplast organelle. The research, conducted by the University of Utah, will use CRISPR/Cas9 to investigate the role and sub-organellar localization of a putative iron transporter protein (PF3D7_1248300) in...