Project Grant R56AG104228
Award Date 9/15/26
Completion Date 8/31/27
Dollars Obligated $2.1M
Federal Agency
Federal Grant Program
Assistance Type
Project Grant
Place of Performance
San Antonio, TX 78229, USA
Similar Awards
- The National Institute on Aging awarded The University of Texas Health Science Center at San Antonio $150,000 on September 18, 2025, under the Aging Research program (CFDA 93.866) to host five international NeurEpiOmics workshops spanning 2025 through 2029. The workshops combine didactic talks by field leaders with hands-on training and discussions to build an interdisciplinary network of researchers fluent in neurology, brain imaging, epidemiology, genetics, multiomics, and ethics. Each...
- The National Institute on Aging awarded New York University $6.203 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to examine peripheral immune markers and vascular dysfunction as contributors to cognitive decline and Alzheimer's disease. The research integrates circulating biomarkers—platelet aggregation, neutrophil activity, and proteomic data—with advanced imaging to assess associations between vascular and immune dysfunction and cerebrovascular burden, amyloid...
- The National Institute on Aging awarded Texas A&M University $640,059 on September 1, 2026, under the Aging Research program (CFDA 93.866) to investigate cerebellar changes in aging and cognitive decline through longitudinal neuroimaging and functional analysis. The project examines how cerebellar structure, white matter circuits, and task-based functional activation change over time in older adults, with particular focus on individuals experiencing subjective cognitive decline—self-reported...
- The National Institute on Aging awarded The University of Texas Health Science Center at San Antonio $1.112 million on September 20, 2025, under the Aging Research program (CFDA 93.866) to deliver advanced training in cross-national research on cognitive aging and Alzheimer's disease and related dementias using harmonized datasets from the Health and Retirement Study and the Harmonized Cognitive Assessment Protocol. The award funds five annual intensive courses for advanced-doctoral,...
- The National Institute on Aging awarded the University of Texas at Austin $10.686 million on September 15, 2025, under the Aging Research program (CFDA 93.866) to investigate remotely-supervised neuromodulation paired with language treatment for the logopenic variant of primary progressive aphasia, a progressive language disorder caused by underlying Alzheimer's disease pathology. The award supports research to enhance proven language treatment for LVPPA by combining it with tailored, home-based...
- The National Institute on Aging awarded the University of Texas Health Science Center at Houston $417,800 on September 15, 2025, for Project Grant R21AG091823 under the Aging Research program (CFDA 93.866). The award funds investigation of senescence induced by iron overload in brain vasculature, with particular focus on sex-dependent differences in vulnerability to iron-induced endothelial damage. The research employs an iron overload model in aged mice, examining the role of the ROBO4...
- The National Institute on Aging awarded The University of Texas Southwestern Medical Center $127,493 on August 1, 2026, under the Aging Research program (CFDA 93.866) to investigate associations between midlife hypertension and brain structure and function changes, and to assess the impact of high-intensity interval training on brain outcomes in middle-aged adults with elevated blood pressure. The project combines retrospective longitudinal analysis with a proof-of-concept randomized...
- The National Institute on Aging awarded the University of Texas Medical Branch at Galveston $1.788 million on January 1, 2026, under the Aging Research program (CFDA 93.866) to investigate the interplay between microglia and tau oligomer polymorphs in cognitive resilience among individuals with Alzheimer's disease neuropathology who remain cognitively intact. The project tests the hypothesis that brain-derived tau oligomers isolated from cognitively resilient individuals exhibit reduced toxicity...
- The National Institute on Aging awarded the University of Virginia $2.877 million on July 1, 2026, under the Aging Research program (CFDA 93.866) to investigate microglia's role in neurovascular coupling and hypertensive cerebral small vessel disease. The project will test the hypothesis that microglial dysregulation of cerebral blood flow leads to hypertensive vascular dementia and endothelial rarefaction as common pathological events with Alzheimer's disease. Aim 1 will employ laser speckle...
- The National Institute on Aging awarded Texas Tech University $447,541 on February 1, 2026, under the Aging Research program (CFDA 93.866, assistance type: Project Grant) to investigate microRNA-driven mitochondrial dysfunction in Alzheimer's disease. The research focuses on validating microRNA PC-5P-12969 as both a biomarker for early Alzheimer's diagnosis and a potential therapeutic target. The recipient will measure microRNA PC-5P-12969 levels in blood, cerebrospinal fluid, and postmortem...