Project Grant R44MH142191
- The National Institute of Mental Health awarded Biosignal Solutions LLC $453,695 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop and validate BrainGain, a mobile neurofeedback platform designed to improve working memory in individuals with schizophrenia. BrainGain translates laboratory-based electroencephalographic neurofeedback (EEG-NFB) technology into a home-use mobile platform consisting of a smartphone application and wireless EEG headband. The...
- The National Institute of Mental Health awarded the University of California, Los Angeles $424,433 on March 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop a framework and online implementation tool for participant engagement in brain-computer interface early feasibility studies. The project addresses a critical gap in BCI research: while participant engagement is recognized as valuable in other clinical domains, BCI early feasibility studies—where people with...
- The National Institute of Mental Health awarded $456,902 to 37Degrees, Inc. on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop INVITREON, a compact integrated platform for long-term neuronal culture incubation, recording, and closed-loop stimulation. The project runs through July 31, 2028, with performance in Chicago, Illinois. INVITREON addresses technical barriers in microelectrode array (MEA) culture systems used for disease modeling, neurotoxicity...
- The National Institute of Mental Health awarded California Institute of Technology $1,417,650 on September 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop instrumentation for synchronized multimodal recording and analysis of human behavior and neural activity during complex, unstructured tasks. The project develops a system to acquire and synchronize behavioral data streams including head-mounted eye tracking to monitor gaze position, egocentric and...
- The National Institute of Neurological Disorders and Stroke awarded $462,148 to The Trustees of Columbia University in the City of New York on July 8, 2026, under the Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative (CFDA 93.372). Columbia will develop and benchmark functional graphene nanoribbon (F-GNR) neural probes as ion-selective, multimodal recording tools for neuroscience. The project addresses the lack of existing tools with sufficient molecular...
- The National Institute of Mental Health awarded Neuralthread Inc. $2.149 million on September 17, 2025, under the Mental Health Research Grants program (CFDA 93.242) to develop TULLEKIT, an integrated deep-brain neural recording system for non-human primates. TULLEKIT combines ultraflexible 384-channel polymer probes, a minimally invasive port system for deep-brain implantation, and a wireless recording headstage to achieve stable, high-density neural recordings in freely moving subjects. The...
- The National Science Foundation Division of Information and Intelligent Systems awarded the University of Massachusetts $430,468 on July 15, 2026, under the Computer and Information Science and Engineering program (CFDA 47.070) to develop neuromorphic wearables for continuous neurophysiological monitoring outside clinical settings. The research develops brain-monitoring wearables that capture the full spectrum of brainwave signals, including high-frequency components during motion, and operate...
- The National Institute of Mental Health awarded the University of Pittsburgh $1,004,971 through the Mental Health Research Grants program (CFDA 93.242) on April 8, 2026, to develop a platform for measuring and analyzing brain activity, cognitive states, behavior, and physiology during multiday neural recordings in individuals undergoing surgical treatment for epilepsy. The project will integrate wearable technology and artificial intelligence for behavioral and physiological monitoring alongside...
- The National Institute of Mental Health awarded Massachusetts General Hospital $453,750 under the Mental Health Research Grants program (CFDA 93.242) on September 1, 2026, to develop a closed-loop system for assessing target network engagement using concurrent transcranial magnetic stimulation and functional MRI. The recipient is developing a flexible radiofrequency coil array (the RF Cap) that enables functional MRI acquisition simultaneously with transcranial magnetic stimulation in a...
- The National Institute of Mental Health awarded the Research Foundation For Mental Hygiene, Inc. $477,335 on July 8, 2026, under the Mental Health Research Grants program (CFDA 93.242) to conduct broadband near infrared spectroscopy research elucidating the role of cortical brain cytochrome c oxidase activity in the pathophysiology of bipolar disorder. The recipient, operating through its New York State Psychiatric Institute division, will use broadband near infrared spectroscopy to directly...
The National Institute of Mental Health awarded Openbci, Inc. $732,736 on August 1, 2026, under the Mental Health Research Grants program (CFDA 93.242) to develop Cyton V2, an affordable, FDA-cleared bioamplifier system with open-source hardware and software for clinical-grade EEG and multimodal physiological monitoring. Openbci will design, manufacture, and obtain FDA clearance for a medical-grade, adaptable, and repairable bioamplifier system intended to address cost barriers that limit widespread deployment of clinical-grade EEG systems and to provide regulatory-compliant tools for neurotech and med-tech startups navigating product validation and market entry. The project encompasses refinement of bioamplifier design and technical specifications, design for manufacturing, and testing to achieve FDA clearance for an initial indication. The finished bioamplifier system will support cost-conscious researchers, clinicians, and medical technology innovators developing new healthcare solutions through physiological monitoring. Work is performed in Brooklyn, New York, with a period of performance from August 1, 2026, through July 31, 2029. This is a Project Grant, the primary assistance type for NIMH research funding.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $732.7k | 7/31/26 |